RetrogeneDB ID: retro_chof_1396

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_280570:561..1225(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CCDC90B
• Ensembl ID: ENSCHOG00000010541
• Aliases: None
• Description: coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:28108]

Sequence

>retro_chof_1396
AGAGACTTCTTAACCACTGTAACCAAGGAAGGATATGATATGAGGCAAGTGACATAACTCCTTTAGAGCAAAGGAAATTA
ACTTTTGATAACCATGCATTGATTCAGGACTTGGAAACTCATGGATTTGACAAAACCTAAGCAGAATCTATTGTATCAGC
TTGATCCACTTTTTCAAATGTCAGCCTGGATACTATCTTAAGGAGATGGTCACTTAAGCTCAACAGGAAATAACAGTACA
GCAACTAATGGTTCATTTGCACTCCATCAGAAAAGAAGTGGTCATCCTAGAGAAAAGTGAATTTGTAAATCTGAGAGCAG
AGAACAAGAAAATGAAAATTGAATTTGACCAAGTTAAGCAGCAACCGATGCATGAAACCAGTCGAATTAGAGCAGATAAT
AAATTGAATATCTACCTAGAAAGGAGCAGAGTAACAGATATGTTTACAGATCAAGAAAAGAAACTTATGGAAACAATCAC
AGAATTTACCAAAAAGGATGCCCAAACCAAAAGTGTTATTTCAGAAACCAGTCATAAAATTGACACTGAAATCGCTTCCT
TAAAAACACTGAAGTAATCTAACAGATTTGAGACAATTCATCATCTTGCAGCCTCAGTGTTTACTTGCCTGGCAATAGCA
TTGAGAATTTATAGATTCTGGAAA

Alignment

ORF - retro_chof_1396 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.93 %
• Parental protein coverage: 87.3 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  RDFLTTITKEGYDMRRV-DITPLEQRKLTFDTHALVQDLETHGFDKTQAE--IMELSTFSNVSLDTIY-K
          RDFLTT.TKEGYDMR.V.DITPLEQRKLTFD.HAL.QDLETHGFDKT.AE......STFSNVSLDTI..K
Retrocopy RDFLTTVTKEGYDMRQV<DITPLEQRKLTFDNHALIQDLETHGFDKT*AESIVSA*STFSNVSLDTIL<K

Parental  EMVTQAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKHQLMHETSRIRADNKLDI
          EMVT.AQQEITVQQLM.HL.SIRK..VILEKSEF.NLRAEN.KMKIE.DQVK.Q.MHETSRIRADNKL.I
Retrocopy EMVT*AQQEITVQQLMVHLHSIRKEVVILEKSEFVNLRAENKKMKIEFDQVKQQPMHETSRIRADNKLNI

Parental  NLERSRVTDMFTDQEKKLMETTTEFTKKDTQTKNVISETSHKIDTEIASLKTLMESNRLETIRYLAASVF
          .LERSRVTDMFTDQEKKLMET.TEFTKKD.QTK.VISETSHKIDTEIASLKTL..SNR.ETI..LAASVF
Retrocopy YLERSRVTDMFTDQEKKLMETITEFTKKDAQTKSVISETSHKIDTEIASLKTLK*SNRFETIHHLAASVF

Parental  TCLAIALGFYRFWK
          TCLAIAL..YRFWK
Retrocopy TCLAIALRIYRFWK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1396 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 18 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000010541	2 retrocopies	retro_chof_1396 , retro_chof_780,
Callithrix jacchus	ENSCJAG00000014547	1 retrocopy	retro_cjac_219,
Homo sapiens	ENSG00000137500	1 retrocopy	retro_hsap_3050,
Macaca mulatta	ENSMMUG00000020154	2 retrocopies	retro_mmul_1880, retro_mmul_773,
Nomascus leucogenys	ENSNLEG00000016478	1 retrocopy	retro_nleu_1644,
Ochotona princeps	ENSOPRG00000004144	2 retrocopies	retro_opri_197, retro_opri_682,
Pongo abelii	ENSPPYG00000003736	1 retrocopy	retro_pabe_2525,
Pan troglodytes	ENSPTRG00000004129	1 retrocopy	retro_ptro_1990,
Pteropus vampyrus	ENSPVAG00000005459	1 retrocopy	retro_pvam_614,
Rattus norvegicus	ENSRNOG00000009462	1 retrocopy	retro_rnor_868,
Tupaia belangeri	ENSTBEG00000014665	2 retrocopies	retro_tbel_3436, retro_tbel_4221,
Tarsius syrichta	ENSTSYG00000011196	1 retrocopy	retro_tsyr_710,
Tursiops truncatus	ENSTTRG00000003998	1 retrocopy	retro_ttru_445,
Vicugna pacos	ENSVPAG00000007753	1 retrocopy	retro_vpac_366,