RetrogeneDB ID: retro_chof_256

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: GeneScaffold_5554:45446..45863(+)
• Located in intron of: ENSCHOG00000003976

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RAB18
• Ensembl ID: ENSCHOG00000005565
• Aliases: None
• Description: RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:14244]

Sequence

>retro_chof_256
AAACTTGCAATTTGGAACACTGCCGGTGAAGAGCAGTTCGGAACTTTAACTCCCAGCTATTATAGAGGTGCATGGGGTGT
TATATTAGTTTATGATGACACAAGAAGAGACGCCTCTCATAAGCTGAATAATTGGTTAAATGAATTGGAAACATACTATA
CAATAAGTGACATAGTAAACATGCTAGTTGGAAATAAAATTGATAAGGAATATCATGAAGTTGATAGAAACAAAGGCATG
AAATTTGCATGCAAGTATTCCATGTTATTCACAGAGGCAAGTGCAGAAACCTGTGATGGTATCCAATCTACCTTTCAGGA
ACTTGTTGATAAGATCATTCAGACCCCTAGACTGTAGGAAAGTGAGAACCAGAATAAAAGAGAAAAACAGTCACGCAGGG
AAGAAGGACAAGGAGGG

Alignment

ORF - retro_chof_256 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.76 %
• Parental protein coverage: 57.55 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KWTIWKYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFLKLDNWLNELETYCTRNDIVNMLVGNKID
          K..IW...TAG.E.F.TLTPSYYRGA.GVILVYD.TRRD...KL.NWLNELETY.T..DIVNMLVGNKID
Retrocopy KLAIW--NTAGEEQFGTLTPSYYRGAWGVILVYDDTRRDASHKLNNWLNELETYYTISDIVNMLVGNKID

Parental  KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREERQG
          KE..EVDRN.G.KFA.K.SMLF.EASA.TCDG.Q..F.ELV.KIIQTP.L.ESENQNK..K.S.REE.QG
Retrocopy KEYHEVDRNKGMKFACKYSMLFTEASAETCDGIQSTFQELVDKIIQTPRL*ESENQNKREKQSRREEGQG

Parental  G
          G
Retrocopy G

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_256 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 16 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000009871	1 retrocopy	retro_btau_1691,
Choloepus hoffmanni	ENSCHOG00000005565	4 retrocopies	retro_chof_2391, retro_chof_256 , retro_chof_396, retro_chof_846,
Cavia porcellus	ENSCPOG00000002234	2 retrocopies	retro_cpor_633, retro_cpor_652,
Dipodomys ordii	ENSDORG00000014338	1 retrocopy	retro_dord_419,
Monodelphis domestica	ENSMODG00000008253	1 retrocopy	retro_mdom_146,
Oryctolagus cuniculus	ENSOCUG00000022307	2 retrocopies	retro_ocun_1699, retro_ocun_841,
Otolemur garnettii	ENSOGAG00000028015	2 retrocopies	retro_ogar_2587, retro_ogar_2973,
Rattus norvegicus	ENSRNOG00000018972	2 retrocopies	retro_rnor_2744, retro_rnor_2962,
Sarcophilus harrisii	ENSSHAG00000007613	1 retrocopy	retro_shar_281,