RetrogeneDB ID: retro_ggor_2107

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 4:108330028..108330731(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PCNA
• Ensembl ID: ENSGGOG00000001695
• Aliases: None
• Description: None

Sequence

>retro_ggor_2107
GCCTGCTGGGACAACAGTTCAAGTAGGTGAACCTACACAGCATGAAAGTATCACACATTTCCTTAGTGCAGCTAACCCTG
TGTGACCAGGGCTTCAACACATACCACTGTGACCACAACCTAGCCATGAGCATGAGCCTCACCAGCATGTCCAAAATGCT
AAAATACAACGATGGCAGTGAAGACATCACTACATGGAGGGCTGAAGGTACCATGGATCTCTTGGTGCTAGAATTTGAAG
CACTAAATCAAGAGAACTTTTAGACTGTGAATTGAAGTTAATGACTCTAGATGTTGAGCAACTTGACATTCCAGAACAAG
AGTACAGCTGTGTAATAAAGATGCATTCTAGTGAATTTGTTCATATATGCCAAGATCTCAGTCATATTGGAGAGTCTTTT
ATAACTTCTTATGCAAAAGATGGAGTGAAATTTTCTGCAAATGGAGAACTTGGACATGGAAACATTGCCACAAACAAGTA
ATTACAATAAAGAAGAGGAGGCTGTTGCCATAATGATGAATGGGCCAGTTCAGCTAACTTTTGCACTAAGTTACTTAAAT
TTCTTTATAACAGGCACTCCACTCTCTCTTCCCAGTAACACTCAGTATGTCTGCAGATGCACCCCTTGCTGTAGAGTATA
AGATTGCCGGATATGGAACATTTAAAGTATTATTTGGCTCCCAAAATTGAGGATGAAAAAGGA

Alignment

ORF - retro_ggor_2107 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.22 %
• Parental protein coverage: 90.04 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  ACWDISSSG-VNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCA-GNEDIITLRAE
          ACWD.SSS..VNL.SM..SH.SLVQLTL...GF.TY.CD.NLAM...LTSMSK.LK...G.EDI.T.RAE
Retrocopy ACWDNSSSR<VNLHSMKVSHISLVQLTLCDQGFNTYHCDHNLAMSMSLTSMSKMLKYNDGSEDITTWRAE

Parental  DNADTLALVFEAPNQE-KVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISC
          ...D.L.L.FEA.NQE....D.E.KLM.LDVEQL.IPEQEYSCV.KM.S.EF..IC.DLSHIG.....S.
Retrocopy GTMDLLVLEFEALNQE<ELLDCELKLMTLDVEQLDIPEQEYSCVIKMHSSEFVHICQDLSHIGESFITSY

Parental  AKDGVKFSASGELGNGNIKLSQ-TSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLS-STVTLSMS
          AKDGVKFSA.GELG.GNI.......N...E..AV.I.MN.PVQLTFAL.YLNFF...TPLS...VTLSMS
Retrocopy AKDGVKFSANGELGHGNIATNK>NYNKEEE--AVAIMMNGPVQLTFALSYLNFFITGTPLS>FPVTLSMS

Parental  ADVPLVVEYKIA-DMGHLKYYLAPKIEDEEG
          AD.PL.VEYKIA.DM.HLKYYLAPKIEDE.G
Retrocopy ADAPLAVEYKIA>DMEHLKYYLAPKIEDEKG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	8.34 RPM
SRP007412_cerebellum	0.00 RPM	11.90 RPM
SRP007412_heart	0.00 RPM	3.63 RPM
SRP007412_kidney	0.00 RPM	18.32 RPM
SRP007412_liver	0.00 RPM	14.14 RPM
SRP007412_testis	0.52 RPM	61.95 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2107 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2107 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 43 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000009089	1 retrocopy	retro_amel_1719,
Canis familiaris	ENSCAFG00000006030	2 retrocopies	retro_cfam_1626, retro_cfam_946,
Callithrix jacchus	ENSCJAG00000021278	3 retrocopies	retro_cjac_2159, retro_cjac_2175, retro_cjac_930,
Cavia porcellus	ENSCPOG00000009242	1 retrocopy	retro_cpor_315,
Erinaceus europaeus	ENSEEUG00000003069	1 retrocopy	retro_eeur_358,
Echinops telfairi	ENSETEG00000006577	3 retrocopies	retro_etel_1152, retro_etel_1539, retro_etel_2217,
Felis catus	ENSFCAG00000009068	2 retrocopies	retro_fcat_1363, retro_fcat_1729,
Homo sapiens	ENSG00000132646	3 retrocopies	retro_hsap_3067, retro_hsap_4817, retro_hsap_857,
Gorilla gorilla	ENSGGOG00000001695	2 retrocopies	retro_ggor_2107 , retro_ggor_700,
Myotis lucifugus	ENSMLUG00000001693	1 retrocopy	retro_mluc_1658,
Macaca mulatta	ENSMMUG00000013259	3 retrocopies	retro_mmul_1059, retro_mmul_1960, retro_mmul_2570,
Monodelphis domestica	ENSMODG00000011649	1 retrocopy	retro_mdom_933,
Mustela putorius furo	ENSMPUG00000006195	2 retrocopies	retro_mputfur_330, retro_mputfur_629,
Mus musculus	ENSMUSG00000027342	1 retrocopy	retro_mmus_114,
Nomascus leucogenys	ENSNLEG00000007726	2 retrocopies	retro_nleu_2192, retro_nleu_424,
Otolemur garnettii	ENSOGAG00000033161	2 retrocopies	retro_ogar_1258, retro_ogar_2960,
Procavia capensis	ENSPCAG00000010500	1 retrocopy	retro_pcap_130,
Pongo abelii	ENSPPYG00000010795	3 retrocopies	retro_pabe_2542, retro_pabe_3745, retro_pabe_690,
Pan troglodytes	ENSPTRG00000013222	3 retrocopies	retro_ptro_2068, retro_ptro_3206, retro_ptro_595,
Pteropus vampyrus	ENSPVAG00000002865	1 retrocopy	retro_pvam_193,
Rattus norvegicus	ENSRNOG00000021264	1 retrocopy	retro_rnor_1035,
Sorex araneus	ENSSARG00000004070	1 retrocopy	retro_sara_640,
Sus scrofa	ENSSSCG00000030642	1 retrocopy	retro_sscr_113,
Tursiops truncatus	ENSTTRG00000015368	2 retrocopies	retro_ttru_1868, retro_ttru_440,