RetrogeneDB ID: retro_ggor_550

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 10:124899973..124900228(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000026027
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: C19ORF53
• Ensembl ID: ENSGGOG00000027024
• Aliases: None
• Description: None

Sequence

>retro_ggor_550
AGCGAAGAGGCAGCGGCGGCCTCTGAAAGGAACCGGGGCCGCAGGAAAGACGGTCGTGTTACAGCTCCCAAGAAGGCGTG
CGTCGGTCAGCAGCAAAAGCTTAATAAGAATCTAGAAGTCAGGATCTGGAAGAAGATCGAACATGCCATGGTGATGAAAG
CCAGCAACAGCCTGCCCAAGAAGCTGGCACTGCTGAAGGCCCCGACCAAGAAGAAAGGGGCGGCTGCTGCCACCTCCTCC
AACAAGACACCTTCC

Alignment

ORF - retro_ggor_550 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.18 %
• Parental protein coverage: 84.85 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  SKTAAAASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKKLALLKAPAK
          S..AAAASE.NRG.RK.GRV.APKKA.V.QQQKL.KNLEV.I.KKIEH..VMKAS.SLPKKLALLKAP.K
Retrocopy SEEAAAASERNRGRRKDGRVTAPKKACVGQQQKLNKNLEVRIWKKIEHAMVMKASNSLPKKLALLKAPTK

Parental  KKGAAAATSS-KTPS
          KKGAAAATSS.KTPS
Retrocopy KKGAAAATSSNKTPS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	44.69 RPM
SRP007412_cerebellum	0.08 RPM	20.84 RPM
SRP007412_heart	0.00 RPM	24.17 RPM
SRP007412_kidney	0.00 RPM	30.67 RPM
SRP007412_liver	0.00 RPM	24.32 RPM
SRP007412_testis	0.10 RPM	20.41 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_550 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_550 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_628
Pan troglodytes	retro_ptro_457

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 14 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000002525	1 retrocopy	retro_btau_35,
Callithrix jacchus	ENSCJAG00000004427	3 retrocopies	retro_cjac_1003, retro_cjac_2634, retro_cjac_291,
Homo sapiens	ENSG00000104979	1 retrocopy	retro_hsap_628,
Gorilla gorilla	ENSGGOG00000027024	1 retrocopy	retro_ggor_550 ,
Monodelphis domestica	ENSMODG00000011876	2 retrocopies	retro_mdom_1436, retro_mdom_926,
Nomascus leucogenys	ENSNLEG00000013141	1 retrocopy	retro_nleu_452,
Otolemur garnettii	ENSOGAG00000007185	1 retrocopy	retro_ogar_640,
Procavia capensis	ENSPCAG00000014250	1 retrocopy	retro_pcap_26,
Pan troglodytes	ENSPTRG00000010565	1 retrocopy	retro_ptro_457,
Pteropus vampyrus	ENSPVAG00000006321	1 retrocopy	retro_pvam_1140,
Tursiops truncatus	ENSTTRG00000010354	1 retrocopy	retro_ttru_317,