RetrogeneDB ID: retro_ggor_876

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 12:53714214..53714825(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PSMB3
• Ensembl ID: ENSGGOG00000007067
• Aliases: None
• Description: Proteasome subunit beta type [Source:UniProtKB/TrEMBL;Acc:G3QVX5]

Sequence

>retro_ggor_876
ATGTTTATTATGTCCCATAACCGAGGGGCCTTCATGGCCATGAAGGAGAAGAGCTGTTTGGCTATAGCTGCAGACAGGCG
CTTCGGGATCCAGGCCCAAATGGTTACCACGGACTTCCAGATCTTTCCCATGGGTGACCGGCTGTATATCCATCTGGCCC
GGCTCGTCACTGACATCGAGACCGTTGTCCAGTGCCTCAAGTTCCGGCTGAACCTGTGTGAGTTGAAGGAAGGTCGGCAG
TCAAATCTTATACCCTATGAGCATGGTGGCCAAGGCCTCTTGTCTGAGAAACGTTTGGCCCCTACTATACTGAGCCAGTC
ATTGCTGGGTTGGACCTGAAGACCTTTAAGCCCTTTATTTGCTCTCTAGAGCTCATTGGCTGACCCATGGTGACTGAAGA
CTTTATGGTCGGTGGCACCTGTGCAGAACAAATGTATGAAATGTGCGAGTCCCTCTGGGAGTCCAACATGGATCCAGAAC
AGCTGTTTGAAACCATCTTCCAAGCCATGCTGAATGCTGTGGACCGGGATGCCATGTCAGGCATGGGAGTCATTGTCCAC
ATCACTGAGAAGGACGAAATCACCACCAGGACACTGAAGGCCCTAATGGAC

Alignment

ORF - retro_ggor_876 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.16 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFR
          M.IMS.N.GA.MAMK.K.C.AIAADRRFGIQAQMVTTDFQ.IFPMGDRLYI.LA.L.TD..TV.Q.LKFR
Retrocopy MFIMSHNRGAFMAMKEKSCLAIAADRRFGIQAQMVTTDFQ-IFPMGDRLYIHLARLVTDIETVVQCLKFR

Parental  LNLYELKEGRQ-IKPHTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVS
          LNL.ELKEGRQ..K..TL.......L....FGPYYTEPVIAGLD.KTFKPFICSL.LIG.PMVT.DF.V.
Retrocopy LNLCELKEGRQ<VKSYTL*AWWPRPLV*ETFGPYYTEPVIAGLDLKTFKPFICSLELIG*PMVTEDFMVG

Parental  GTCAEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD
          GTCAEQMY.MCESLWE.NMDPE.LFETI.QAMLNAVDRDA.SGMGVIVHI.EKD.ITTRTLKA.MD
Retrocopy GTCAEQMYEMCESLWESNMDPEQLFETIFQAMLNAVDRDAMSGMGVIVHITEKDEITTRTLKALMD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	28.01 RPM
SRP007412_cerebellum	0.00 RPM	18.36 RPM
SRP007412_heart	0.06 RPM	26.70 RPM
SRP007412_kidney	0.04 RPM	50.29 RPM
SRP007412_liver	0.03 RPM	57.85 RPM
SRP007412_testis	0.21 RPM	29.42 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_876 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_876 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1121
Pongo abelii	retro_pabe_927
Macaca mulatta	retro_mmul_868

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 45 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004363	1 retrocopy	retro_amel_619,
Canis familiaris	ENSCAFG00000016587	2 retrocopies	retro_cfam_135, retro_cfam_532,
Callithrix jacchus	ENSCJAG00000008246	1 retrocopy	retro_cjac_2852,
Equus caballus	ENSECAG00000000987	1 retrocopy	retro_ecab_476,
Erinaceus europaeus	ENSEEUG00000015275	1 retrocopy	retro_eeur_10,
Felis catus	ENSFCAG00000014497	3 retrocopies	retro_fcat_1270, retro_fcat_1442, retro_fcat_784,
Homo sapiens	ENSG00000108294	2 retrocopies	retro_hsap_1121, retro_hsap_2387,
Gorilla gorilla	ENSGGOG00000007067	2 retrocopies	retro_ggor_103, retro_ggor_876 ,
Loxodonta africana	ENSLAFG00000002233	1 retrocopy	retro_lafr_70,
Macropus eugenii	ENSMEUG00000004131	2 retrocopies	retro_meug_1804, retro_meug_551,
Microcebus murinus	ENSMICG00000002997	1 retrocopy	retro_mmur_397,
Macaca mulatta	ENSMMUG00000012363	1 retrocopy	retro_mmul_868,
Monodelphis domestica	ENSMODG00000012614	2 retrocopies	retro_mdom_1722, retro_mdom_1812,
Mus musculus	ENSMUSG00000069744	8 retrocopies	retro_mmus_1449, retro_mmus_1551, retro_mmus_1790, retro_mmus_1938, retro_mmus_2110, retro_mmus_41, retro_mmus_46, retro_mmus_536,
Nomascus leucogenys	ENSNLEG00000000594	3 retrocopies	retro_nleu_1511, retro_nleu_188, retro_nleu_371,
Oryctolagus cuniculus	ENSOCUG00000002598	1 retrocopy	retro_ocun_561,
Pteropus vampyrus	ENSPVAG00000002270	1 retrocopy	retro_pvam_822,
Rattus norvegicus	ENSRNOG00000012938	7 retrocopies	retro_rnor_1016, retro_rnor_2094, retro_rnor_2448, retro_rnor_2537, retro_rnor_2804, retro_rnor_743, retro_rnor_8,
Ictidomys tridecemlineatus	ENSSTOG00000014258	3 retrocopies	retro_itri_527, retro_itri_935, retro_itri_936,
Tupaia belangeri	ENSTBEG00000013010	2 retrocopies	retro_tbel_1387, retro_tbel_2693,