RetrogeneDB ID: retro_mdom_412

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 1:449695886..449696504(+)
• Located in intron of: ENSMODG00000013875

Retrocopy information

• Ensembl ID: ENSMODG00000013869
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSMODG00000007897
• Aliases: None
• Description: None

Sequence

>retro_mdom_412
ATATCCTTATCCTCAGTGGGGATGTCAATTTGGCAGAGTGATTTGGCTTATACACAAGCCATAATGGGCAGTGGGAAGGA
AGATTACACTGACAAAGAATTGCTGATTCTGGGCAGTGGAGATGGGGGTATATTATATGAAATAGTCAAATTGAAACCAA
AGATGGTCACTATGGTAGAGATTGACCAAATGGTGATTGACAGGTGTAAGAAATACATGTGTAAAACATGTGGAGATGTC
TTAGACAATCTTAAAGGAGAGCGCTATCAGGTTCTAATAGAAGACTGTATTCCAGTACTGAAGAGGTATGCCAAAGAAGG
GAGAATGTTTGATTATGTGATTAATGATCTGATAACTGTTCCAATCTCCACATCTCCAGAAGAAGATTCCATGTGGGAAT
TTCTCAGACTGATCCTTGACCTTTCAATGAAAGTATTGAAACATGATGGAAAATACTTTACACAGGGGAACTGTATCAAT
TTGACTGAAGCCTTGACTTTCTACAAAGAACAACTTAGCCGGCTTTATTGTCCTGTGGAATTCTCAAAGGAAATTGTATG
TGTTCCCTCATACATGGAATTGCGGGTATTTTACACTGTTTGGATGAAAACTGAATTT

Alignment

ORF - retro_mdom_412 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.32 %
• Parental protein coverage: 56.28 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  ILILSGDVNLAESDLAYTQAIMGSGKEDYTDKEVLILGGGDGGILYEIVKLKPKMVTMVEIDQMVIDGCK
          I...S.......SDLAYTQAIMGSGKEDYTDKE.LILG.GDGGILYEIVKLKPKMVTMVEIDQMVID.CK
Retrocopy ISLSSVGMSIWQSDLAYTQAIMGSGKEDYTDKELLILGSGDGGILYEIVKLKPKMVTMVEIDQMVIDRCK

Parental  KYMRKTCGDVLDNLKGECYQVLIEDCIPVLKRYAKEGRMFDYVINDLTAVPISTSPEEDSTWEFLRLILD
          KYM.KTCGDVLDNLKGE.YQVLIEDCIPVLKRYAKEGRMFDYVINDL..VPISTSPEEDS.WEFLRLILD
Retrocopy KYMCKTCGDVLDNLKGERYQVLIEDCIPVLKRYAKEGRMFDYVINDLITVPISTSPEEDSMWEFLRLILD

Parental  LSMKVLKHDGKYFTQGNCINLTEALTLYEEQLSRLYCPVEFSKEIVCVPSYMELWVFYTVWKKTEF
          LSMKVLKHDGKYFTQGNCINLTEALT.Y.EQLSRLYCPVEFSKEIVCVPSYMEL.VFYTVW.KTEF
Retrocopy LSMKVLKHDGKYFTQGNCINLTEALTFYKEQLSRLYCPVEFSKEIVCVPSYMELRVFYTVWMKTEF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	1.43 RPM	0.00 RPM
SRP007412_cerebellum	1.31 RPM	0.00 RPM
SRP007412_heart	0.80 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	1.77 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_412 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_412 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000018382	1 retrocopy	retro_btau_1412,
Canis familiaris	ENSCAFG00000013284	3 retrocopies	retro_cfam_1076, retro_cfam_1995, retro_cfam_613,
Callithrix jacchus	ENSCJAG00000033933	1 retrocopy	retro_cjac_518,
Cavia porcellus	ENSCPOG00000006176	2 retrocopies	retro_cpor_729, retro_cpor_889,
Echinops telfairi	ENSETEG00000010098	2 retrocopies	retro_etel_1066, retro_etel_1540,
Homo sapiens	ENSG00000102172	5 retrocopies	retro_hsap_243, retro_hsap_3168, retro_hsap_3193, retro_hsap_3611, retro_hsap_4826,
Gorilla gorilla	ENSGGOG00000003123	3 retrocopies	retro_ggor_1335, retro_ggor_2437, retro_ggor_3009,
Microcebus murinus	ENSMICG00000000192	3 retrocopies	retro_mmur_1421, retro_mmur_1484, retro_mmur_699,
Myotis lucifugus	ENSMLUG00000013185	3 retrocopies	retro_mluc_471, retro_mluc_530, retro_mluc_92,
Macaca mulatta	ENSMMUG00000020392	2 retrocopies	retro_mmul_2003, retro_mmul_2574,
Monodelphis domestica	ENSMODG00000007897	1 retrocopy	retro_mdom_412 ,
Mus musculus	ENSMUSG00000071708	6 retrocopies	retro_mmus_2162, retro_mmus_2170, retro_mmus_2837, retro_mmus_3502, retro_mmus_3628, retro_mmus_994,
Nomascus leucogenys	ENSNLEG00000009955	4 retrocopies	retro_nleu_1664, retro_nleu_2200, retro_nleu_2208, retro_nleu_2755,
Oryctolagus cuniculus	ENSOCUG00000006016	2 retrocopies	retro_ocun_1458, retro_ocun_1918,
Pongo abelii	ENSPPYG00000020182	4 retrocopies	retro_pabe_2649, retro_pabe_2810, retro_pabe_3752, retro_pabe_38,
Pteropus vampyrus	ENSPVAG00000016785	1 retrocopy	retro_pvam_524,
Rattus norvegicus	ENSRNOG00000007688	2 retrocopies	retro_rnor_1934, retro_rnor_938,
Tupaia belangeri	ENSTBEG00000012109	3 retrocopies	retro_tbel_1630, retro_tbel_1893, retro_tbel_3570,
Vicugna pacos	ENSVPAG00000007543	1 retrocopy	retro_vpac_50,