RetrogeneDB ID: retro_mdom_672

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 2:61216750..61217311(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C11orf58
• Ensembl ID: ENSMODG00000007147
• Aliases: None
• Description: chromosome 11 open reading frame 58 [Source:HGNC Symbol;Acc:16990]

Sequence

>retro_mdom_672
GCCCAGCCAGAGTCCCACCCGTACGGGGATGAAGCGCTCAGCCTCCCCTGACTACGATATTGGATCTATCAACTGGGAGG
CAGCCGACTTTAGGCAATGAGGAAAGAAAACAAAAGTTCTTAAGACTAACGGGAGCTGGAAAGAAAGAACACACTGGCCG
TCTTGTTATAGGAGATCACAGGTCGGCATCTCACTTCAGAACAGGGGAAGAAGAAAAGAAAATGAATGAAGACCTGGCGT
CTCAGTATCAACAGAGTATGGACAGTAAATTTTCAGGGAGATACTGGCGACAATTGTGGACTTGGCTTCAGTGAGTTCGA
GGATCCTGATGGGGAAGGTGATGCTCCTGGAAATGACGATGAAGACGATGATGATGATGATGACGACAACGACTCACCTG
ACCCTGAAAGTCCAGAGGACTCTGAAAGTGATTCAGAGTCTGAGAAAGAGGAATCTGTTGAAGACTTACCTGCTACTGAA
CAGCCAGAGGAAGTGGAAGACCCCAAAGCTAAGAAGGATACAAAGAGCAATTACACAATGATGTTTGTTAAGTGCAGTGG
T

Alignment

ORF - retro_mdom_672 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.6 %
• Parental protein coverage: 98.38 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  AARESHPHG-VKRSASPDDDIGSSNWEAAD-LGNEERKQKFLRLMGAGKKEHTGRLVIGDHRSTSHFRTG
          A..ESHP.G..KRSASPD.DIGS.NWEAAD.LGNEERKQKFLRL.GAGKKEHTGRLVIGDHRS.SHFRTG
Retrocopy AQPESHPYG>MKRSASPDYDIGSINWEAAD>LGNEERKQKFLRLTGAGKKEHTGRLVIGDHRSASHFRTG

Parental  EEDKKMNEELESQYQQSMDSKLSGRYRR-HCGLGFSELEDPDGEGDAAGNDDDDDDDDDSPDPESPEDSE
          EE.KKMNE.L.SQYQQSMDSK.SGRY.R..CGLGFSE.EDPDGEGDA.G...................S.
Retrocopy EEEKKMNEDLASQYQQSMDSKFSGRYWR>NCGLGFSEFEDPDGEGDAPGXXXXXXXXXXXXNDSPDPESP

Parental  SDSESE----KEESAEDLPATEQPEEVEDPKAKKDTKSNYKMMFVKSSG
          .DSES.....KEES.EDLPATEQPEEVEDPKAKKDTKSNY.MMFVK.SG
Retrocopy EDSESDSESEKEESVEDLPATEQPEEVEDPKAKKDTKSNYTMMFVKCSG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_672 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_672 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000030220	2 retrocopies	retro_cfam_160, retro_cfam_717,
Callithrix jacchus	ENSCJAG00000009626	1 retrocopy	retro_cjac_3098,
Cavia porcellus	ENSCPOG00000009679	2 retrocopies	retro_cpor_1331, retro_cpor_772,
Equus caballus	ENSECAG00000011778	1 retrocopy	retro_ecab_269,
Felis catus	ENSFCAG00000027747	1 retrocopy	retro_fcat_2016,
Homo sapiens	ENSG00000110696	2 retrocopies	retro_hsap_1408, retro_hsap_3898,
Macropus eugenii	ENSMEUG00000011795	1 retrocopy	retro_meug_1432,
Myotis lucifugus	ENSMLUG00000001589	1 retrocopy	retro_mluc_2604,
Monodelphis domestica	ENSMODG00000007147	2 retrocopies	retro_mdom_1249, retro_mdom_672 ,
Mus musculus	ENSMUSG00000030663	2 retrocopies	retro_mmus_2190, retro_mmus_2616,
Nomascus leucogenys	ENSNLEG00000017719	1 retrocopy	retro_nleu_1425,
Otolemur garnettii	ENSOGAG00000025335	2 retrocopies	retro_ogar_1613, retro_ogar_2569,
Ochotona princeps	ENSOPRG00000000154	1 retrocopy	retro_opri_761,
Pongo abelii	ENSPPYG00000003458	2 retrocopies	retro_pabe_1166, retro_pabe_3178,
Rattus norvegicus	ENSRNOG00000020436	1 retrocopy	retro_rnor_622,