RetrogeneDB ID: retro_mmus_651

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 10:69422680..69423363(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: St13
• Ensembl ID: ENSMUSG00000022403
• Aliases: St13, 1110007I03Rik, 3110002K08Rik, AW555194, HIP, HOP, HSPABP, HSPABP1, PRO0786, SNC6, p48
• Description: suppression of tumorigenicity 13 [Source:MGI Symbol;Acc:MGI:1917606]

Sequence

>retro_mmus_651
ACTGACGCCATCAAGCTAAACCCTCGCCTGGCTGTTCCACACTCCAAAAGAGTCAGTGTCTTCATCAAATGACAGAGCCA
AATTCTTCCATCCCAGGCCTCGACAAAGCCACTGAAATAAACCCTGATTCTGTTCAGCCATGCAAATGGCCAGGGAAAGC
GCACAGACTCCTGAGTCACTGGGAAGAAGCAGCTCATGATCTTGCCCTTGCCTTTAAGCTGGATTATGATGAGGATGCCC
GTGAAATGCTGAAAGAAGTCCAACCTCAGGCTCAAAACTGTGCTGAAATCAGAGGAAGTATGATCAAAAACGTGAAGAGG
AAGAGATAAAGAAACAGACAAGGTCTAGAAGGCTCAAGAGGAGCATGAGAGAGCACGAAGCAACCAGAAGATGATCCGGA
GCTCAGTGTGGCTCTTTTCCAGGTGGTTTTCCTGAGGGAATGCCTGGTAATTTCCCTGGAGACATGCCCGGAACAGGAGG
GGGCATGCCAGGACTGTCAGGAATGCCTGGACTTGCTGAAACCCTCAGTGATCAGAGGTTCTTGTACCCACTCAGGATCC
TGAAGTCATGGTGGCTTTCTAGCATGTGGCCCAGAACCCAGCACATATTTATCAAGATATCAGAGCGACCCAAAGGTTAT
GGATCTCATCACTACACTGACAGCCATGTATGGAAGTCAATCA

Alignment

ORF - retro_mmus_651 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 60.74 %
• Parental protein coverage: 63.34 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  TDAIKLNPRLAILYAKRASVFVKLQ-KPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLA
          TDAIKLNPRLA....KR.SVF.K.Q..PN..I...D.A.EINPDS.QP.KW.GKAHRLL.HWEEAAHDLA
Retrocopy TDAIKLNPRLAVPHSKRVSVFIK*Q<EPNSSIPGLDKATEINPDSVQPCKWPGKAHRLLSHWEEAAHDLA

Parental  LACKLDYDEDASAMLREVQPRAQKIAE-HRRKYERKREEREIKE--RIERVKKAREEHERAQREEEARRQ
          LA.KLDYDEDA..ML.EVQP.AQ..AE...RKY..KREE.EIK...R..R.K....EHE...R...A..Q
Retrocopy LAFKLDYDEDAREMLKEVQPQAQNCAE<NQRKYDQKREEEEIKKQTRSRRLKRSMREHEATRR*SGA--Q

Parental  SGSQYGSFPGGFPGGMPGNFPGGMPGMGGAMPGMAGMAGMPGLNEILSD-PEVLAAMQDPEVMVAFQDVA
          .GS..G.FP.G.PG....NFPG.MPG.GG.MPG..GM...PGL.E.LSD..EVL...QDPEVMVAF..VA
Retrocopy CGSFPGGFPEGMPG----NFPGDMPGTGGGMPGLSGM---PGLAETLSD<SEVLVPTQDPEVMVAF*HVA

Parental  QNPSNM-SKYQSNPK-VMNLISKLSAKFGGQS
          QNP.....K....PK.VM.LI..L.A..G.QS
Retrocopy QNPAHI>IKISERPK>VMDLITTLTAMYGSQS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	130.11 RPM
SRP007412_cerebellum	0.00 RPM	143.51 RPM
SRP007412_heart	0.00 RPM	85.17 RPM
SRP007412_kidney	0.33 RPM	200.00 RPM
SRP007412_liver	0.05 RPM	184.85 RPM
SRP007412_testis	0.00 RPM	210.77 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_651 was not detected

EST

No EST(s) were mapped for retro_mmus_651 retrocopy.

TSS

No TSS is located nearby retro_mmus_651 retrocopy 5' end.

Lab

retro_mmus_651 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_651 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Rattus norvegicus	retro_rnor_1725

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 127 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000005227	1 retrocopy	retro_acar_2,
Ailuropoda melanoleuca	ENSAMEG00000013880	1 retrocopy	retro_amel_135,
Bos taurus	ENSBTAG00000006202	4 retrocopies	retro_btau_254, retro_btau_427, retro_btau_621, retro_btau_658,
Canis familiaris	ENSCAFG00000001139	14 retrocopies	retro_cfam_1029, retro_cfam_1101, retro_cfam_1122, retro_cfam_1239, retro_cfam_1467, retro_cfam_1830, retro_cfam_1950, retro_cfam_1958, retro_cfam_247, retro_cfam_262, retro_cfam_582, retro_cfam_808, retro_cfam_901, retro_cfam_969,
Choloepus hoffmanni	ENSCHOG00000012676	1 retrocopy	retro_chof_2222,
Callithrix jacchus	ENSCJAG00000004644	11 retrocopies	retro_cjac_1843, retro_cjac_1953, retro_cjac_2177, retro_cjac_2275, retro_cjac_2789, retro_cjac_3123, retro_cjac_3570, retro_cjac_4019, retro_cjac_488, retro_cjac_640, retro_cjac_685,
Cavia porcellus	ENSCPOG00000002290	4 retrocopies	retro_cpor_1394, retro_cpor_1477, retro_cpor_166, retro_cpor_961,
Felis catus	ENSFCAG00000011847	2 retrocopies	retro_fcat_920, retro_fcat_987,
Homo sapiens	ENSG00000100380	16 retrocopies	retro_hsap_1055, retro_hsap_1203, retro_hsap_178, retro_hsap_201, retro_hsap_2078, retro_hsap_2189, retro_hsap_2853, retro_hsap_3206, retro_hsap_3907, retro_hsap_4009, retro_hsap_4876, retro_hsap_500, retro_hsap_619, retro_hsap_756, retro_hsap_812, retro_hsap_986,
Gorilla gorilla	ENSGGOG00000026747	16 retrocopies	retro_ggor_1600, retro_ggor_1734, retro_ggor_1791, retro_ggor_1975, retro_ggor_2177, retro_ggor_2634, retro_ggor_2692, retro_ggor_277, retro_ggor_3045, retro_ggor_629, retro_ggor_666, retro_ggor_749, retro_ggor_788, retro_ggor_832, retro_ggor_833, retro_ggor_938,
Microcebus murinus	ENSMICG00000008875	2 retrocopies	retro_mmur_481, retro_mmur_954,
Myotis lucifugus	ENSMLUG00000007764	2 retrocopies	retro_mluc_1088, retro_mluc_2021,
Macaca mulatta	ENSMMUG00000019118	3 retrocopies	retro_mmul_1842, retro_mmul_402, retro_mmul_438,
Monodelphis domestica	ENSMODG00000013042	2 retrocopies	retro_mdom_1087, retro_mdom_31,
Mus musculus	ENSMUSG00000022403	2 retrocopies	retro_mmus_2997, retro_mmus_651 ,
Nomascus leucogenys	ENSNLEG00000015378	17 retrocopies	retro_nleu_1142, retro_nleu_1155, retro_nleu_1606, retro_nleu_1852, retro_nleu_2075, retro_nleu_2088, retro_nleu_2376, retro_nleu_2404, retro_nleu_247, retro_nleu_2555, retro_nleu_2765, retro_nleu_3121, retro_nleu_3122, retro_nleu_319, retro_nleu_447, retro_nleu_552, retro_nleu_988,
Otolemur garnettii	ENSOGAG00000016932	1 retrocopy	retro_ogar_224,
Pongo abelii	ENSPPYG00000011858	14 retrocopies	retro_pabe_1004, retro_pabe_2181, retro_pabe_2361, retro_pabe_2657, retro_pabe_2885, retro_pabe_3183, retro_pabe_3673, retro_pabe_3794, retro_pabe_437, retro_pabe_554, retro_pabe_727, retro_pabe_763, retro_pabe_798, retro_pabe_880,
Pteropus vampyrus	ENSPVAG00000011908	2 retrocopies	retro_pvam_1104, retro_pvam_393,
Rattus norvegicus	ENSRNOG00000019070	8 retrocopies	retro_rnor_1360, retro_rnor_1725, retro_rnor_1798, retro_rnor_1976, retro_rnor_2204, retro_rnor_2372, retro_rnor_2481, retro_rnor_2543,
Sarcophilus harrisii	ENSSHAG00000000319	2 retrocopies	retro_shar_70, retro_shar_767,
Sus scrofa	ENSSSCG00000000071	1 retrocopy	retro_sscr_428,
Ictidomys tridecemlineatus	ENSSTOG00000003165	1 retrocopy	retro_itri_88,