RetrogeneDB ID: retro_mmus_749

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 11:102124073..102124637(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000082045
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Ppih
• Ensembl ID: ENSMUSG00000060288
• Aliases: Ppih, 1100001J08Rik, 2010111B15Rik, 4833408F11Rik, AI464484, CYP-20, CYPH, D4Wsu43e
• Description: peptidyl prolyl isomerase H [Source:MGI Symbol;Acc:MGI:106499]

Sequence

>retro_mmus_749
ATGGCGGTGGCAAATTCAAGTCCAGTCAATCCAGTGGTCTTCTTCGATGTCAGCATTGGCGGCCAGGAAGTTGGTCGCAT
GAAAATCGAGCTCTTTGCAGACGTGGTGCCTAAGACGGCAGAGAACTTTAGGCAATTCTGCACCGGAGAGTTCAGAAAAG
ATGGCGTTCCGATAGGATACAAAGGAAGCACCTTCCACAGGGTCATAAAGGATTTCATGATTCAGGGTGGAGATTTTGTT
AATGGCGATGGCACTGGAGTCGCCAGTATTTACCGGGGTCCATTTGCGGATGAAAATTTTAAACTTAGACACTCTGCTCC
AGGCCTGCTTTCCATGGCAAACAGTGGTCCCAGTACAAATGGCTGCCAGTTCTTTATCACGTGTTCTAAGTGTGATTGGC
TGGATGGAAAGCATGTAGTGTTTGGAAAAATCATTGACGGACTTCTAGTGATGAGGAAGATCGAGTTCCAGGCTCCTTTG
GGAAAGAGAGTTCAAGCTTGGACCCATTCATTAACCTGCCCAGCACTTACTGGGATTTTGGCTCTGATCCTGATGCCCAC
TGAA

Alignment

ORF - retro_mmus_749 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 100. %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIK
          MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIK
Retrocopy MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIK

Parental  DFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVV
          DFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVV
Retrocopy DFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVV

Parental  FGKIIDGLLVMRKIEFQAPLGKRVQAWTHSLTCPALTGILALILMPTE
          FGKIIDGLLVMRKIEFQAPLGKRVQAWTHSLTCPALTGILALILMPTE
Retrocopy FGKIIDGLLVMRKIEFQAPLGKRVQAWTHSLTCPALTGILALILMPTE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	4.30 RPM
SRP007412_cerebellum	0.00 RPM	4.82 RPM
SRP007412_heart	0.00 RPM	3.14 RPM
SRP007412_kidney	0.00 RPM	5.41 RPM
SRP007412_liver	0.00 RPM	3.66 RPM
SRP007412_testis	0.00 RPM	10.02 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_749 was not detected

EST

2 EST(s) were mapped to retro_mmus_749 retrocopy

EST ID	Start	End	Identity	Match	Mis-match	Score
AA163293	102124102	102124240	100	138	0	138
AI048504	102124096	102124260	99.4	162	1	160

TSS

No TSS is located nearby retro_mmus_749 retrocopy 5' end.

Lab

retro_mmus_749 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_749 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000003145	5 retrocopies	retro_cjac_129, retro_cjac_1886, retro_cjac_2205, retro_cjac_3120, retro_cjac_4110,
Macropus eugenii	ENSMEUG00000001691	1 retrocopy	retro_meug_1699,
Macaca mulatta	ENSMMUG00000013129	1 retrocopy	retro_mmul_1124,
Mustela putorius furo	ENSMPUG00000013966	2 retrocopies	retro_mputfur_285, retro_mputfur_542,
Mus musculus	ENSMUSG00000060288	7 retrocopies	retro_mmus_2563, retro_mmus_2873, retro_mmus_3195, retro_mmus_3709, retro_mmus_749 , retro_mmus_913, retro_mmus_977,
Otolemur garnettii	ENSOGAG00000014937	1 retrocopy	retro_ogar_2368,
Procavia capensis	ENSPCAG00000011139	1 retrocopy	retro_pcap_81,
Rattus norvegicus	ENSRNOG00000008489	1 retrocopy	retro_rnor_2911,