RetrogeneDB ID: retro_pabe_1768

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 1_random:27426896..27427475(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SLC25A3
• Ensembl ID: ENSPPYG00000004858
• Aliases: None
• Description: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]

Sequence

>retro_pabe_1768
GCTAGCGGCTGCGCCCAGACTTTCTTCGGCTACTCCCTGCAGGGCTTCAAGTTCGGCCTTTACGAGGTCTTCAAGATCCG
CTACGCGGAGCTCCTGGGCCCAGAGAAGCCCTACGGGTGGAGAACCGGCCTGTACCTTTTCGCCTGGGCCAGCGCCGAGT
TCTTCGCCGACATCTCCCTGGCGCCCATGGAGGCTGTCAAGGTCCGCGTGCAGACGCGACCGGGCTACGCCAGCACCCTG
CGAGCCGCGGCGCCCAAGATGTAGGGCGAGGAGGGCCTGTGGGCCATCTGCAAGGGCGTGGCGCCGCTGTGGCTAAGGCA
GATCCCCTACACCATGATGAAGTTCGCCTGCTTCCAGTGCACGGTGGAGGAGCTCTACAGGTACGCCGTGCCCAAGCCCC
AGAGCCAGTGCACCAAGGCCAAGCAGCTGGGCATCACCTCCGTGGCCAGCTACATCGCTGGCGTCTTCTGCGCTGTCGTG
TCCCACCCCGCCGACTCCGTGGTGTCTGTGCTGCACAAGGAGAAGGGCAGCACGGCCCTGGGCGTCCTCCGGAGACTGGG
GTTCGCGGGCGTGTGGAAG

Alignment

ORF - retro_pabe_1768 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.28 %
• Parental protein coverage: 53.87 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  AKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR
          A.G.A.TF.GYS.QG..KFG.YEVFK..Y...LG.E..Y.WRT.LYL.A.ASAEFFADI.LAPMEA.KVR
Retrocopy ASGCAQTFFGYSLQGF-KFGLYEVFKIRYAELLGPEKPYGWRTGLYLFAWASAEFFADISLAPMEAVKVR

Parental  IQTQPGYANPLLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECS
          .QT.PGYA..L.R.AAPKM..EEGL.A..KGVAPLW.RQIPYTMMKFACF..TVE.LY...VPKP.S.C.
Retrocopy VQTRPGYASTL-RAAAPKM*GEEGLWAICKGVAPLWLRQIPYTMMKFACFQCTVEELYRYAVPKPQSQCT

Parental  KPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWK
          K..QL..T.VA.YIAGVFCA.VSHPADSVVSVL.KEKGS.A..VL.RLGF.GVWK
Retrocopy KAKQLGITSVASYIAGVFCAVVSHPADSVVSVLHKEKGSTALGVLRRLGFAGVWK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	54.79 RPM
SRP007412_cerebellum	0.00 RPM	67.73 RPM
SRP007412_heart	0.00 RPM	185.26 RPM
SRP007412_kidney	0.00 RPM	88.44 RPM
SRP007412_liver	0.00 RPM	57.29 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1768 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1768 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1768 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 27 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000013232	1 retrocopy	retro_acar_35,
Bos taurus	ENSBTAG00000012890	1 retrocopy	retro_btau_172,
Canis familiaris	ENSCAFG00000006545	1 retrocopy	retro_cfam_880,
Callithrix jacchus	ENSCJAG00000002392	2 retrocopies	retro_cjac_3315, retro_cjac_812,
Dipodomys ordii	ENSDORG00000011431	1 retrocopy	retro_dord_321,
Equus caballus	ENSECAG00000015135	1 retrocopy	retro_ecab_481,
Echinops telfairi	ENSETEG00000012678	1 retrocopy	retro_etel_1748,
Homo sapiens	ENSG00000075415	1 retrocopy	retro_hsap_392,
Gorilla gorilla	ENSGGOG00000015886	1 retrocopy	retro_ggor_394,
Latimeria chalumnae	ENSLACG00000007024	1 retrocopy	retro_lcha_4,
Macropus eugenii	ENSMEUG00000016593	2 retrocopies	retro_meug_405, retro_meug_658,
Microcebus murinus	ENSMICG00000003520	1 retrocopy	retro_mmur_298,
Myotis lucifugus	ENSMLUG00000008330	1 retrocopy	retro_mluc_1184,
Macaca mulatta	ENSMMUG00000023036	1 retrocopy	retro_mmul_496,
Monodelphis domestica	ENSMODG00000007717	2 retrocopies	retro_mdom_2026, retro_mdom_293,
Mus musculus	ENSMUSG00000061904	1 retrocopy	retro_mmus_1959,
Nomascus leucogenys	ENSNLEG00000005973	1 retrocopy	retro_nleu_2402,
Oryctolagus cuniculus	ENSOCUG00000011847	1 retrocopy	retro_ocun_390,
Otolemur garnettii	ENSOGAG00000012222	2 retrocopies	retro_ogar_1816, retro_ogar_2052,
Pongo abelii	ENSPPYG00000004858	1 retrocopy	retro_pabe_1768 ,
Pan troglodytes	ENSPTRG00000005333	1 retrocopy	retro_ptro_302,
Pteropus vampyrus	ENSPVAG00000005890	1 retrocopy	retro_pvam_212,
Sorex araneus	ENSSARG00000001149	1 retrocopy	retro_sara_262,
Ictidomys tridecemlineatus	ENSSTOG00000027633	2 retrocopies	retro_itri_485, retro_itri_90,
Tupaia belangeri	ENSTBEG00000014548	1 retrocopy	retro_tbel_1792,
Tursiops truncatus	ENSTTRG00000004739	1 retrocopy	retro_ttru_692,
Vicugna pacos	ENSVPAG00000004704	1 retrocopy	retro_vpac_455,