RetrogeneDB ID: retro_pabe_1785

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 20:25015139..25015574(+)
• Located in intron of: ENSPPYG00000010819

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSPPYG00000013315
• Aliases: None
• Description: None

Sequence

>retro_pabe_1785
GTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTTTCCTGATCCAAACAAGTTTCACTGTTTTCAGCT
AACAGTAACACCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACCGAAGTTCCCCATGTGTACAACATGA
TGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGCGGAAGTATGTCTGAGTTTACTG
AGAGAACATTCAATTGACGGCACTGGCTGGGCTCCCATGAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTTGTT
TACTGATCTTTTGAATTTTGATGATCCACTGAATATTGAAGCTGCAGAACATCATTTGCAGGACAAGGAGGACTTCCAGA
ATAAAGTGGACAACTACATCAAGTGTTATGCCAGA

Alignment

ORF - retro_pabe_1785 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.41 %
• Parental protein coverage: 78.38 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  VAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNIT
          VAELEANLPCTCKVHFPDPNK.HCFQLTVTPDEGYYQGGKFQFETEVP..YNM.PPKVKCLTKIWHPNIT
Retrocopy VAELEANLPCTCKVHFPDPNKFHCFQLTVTPDEGYYQGGKFQFETEVPHVYNMMPPKVKCLTKIWHPNIT

Parental  ETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYI
          ET.E.CLSLLREHSIDGTGWAP.RTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHL.DKEDF.NKVD.YI
Retrocopy ETAEVCLSLLREHSIDGTGWAPMRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLQDKEDFQNKVDNYI

Parental  KRYAR
          K.YAR
Retrocopy KCYAR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.11 RPM	9.23 RPM
SRP007412_cerebellum	0.12 RPM	6.69 RPM
SRP007412_heart	0.09 RPM	6.41 RPM
SRP007412_kidney	0.20 RPM	6.36 RPM
SRP007412_liver	0.15 RPM	12.00 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1785 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1785 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1785 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2439
Pan troglodytes	retro_ptro_1410
Gorilla gorilla	retro_ggor_1519
Macaca mulatta	retro_mmul_628

---

Parental genes homology:

Parental genes homology involve 24 parental genes, and 59 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008551	1 retrocopy	retro_amel_572,
Bos taurus	ENSBTAG00000026114	2 retrocopies	retro_btau_1698, retro_btau_948,
Canis familiaris	ENSCAFG00000012363	1 retrocopy	retro_cfam_1275,
Callithrix jacchus	ENSCJAG00000000476	3 retrocopies	retro_cjac_2378, retro_cjac_2980, retro_cjac_3219,
Cavia porcellus	ENSCPOG00000006368	1 retrocopy	retro_cpor_1122,
Dasypus novemcinctus	ENSDNOG00000000506	2 retrocopies	retro_dnov_1301, retro_dnov_132,
Equus caballus	ENSECAG00000011687	1 retrocopy	retro_ecab_158,
Echinops telfairi	ENSETEG00000009230	1 retrocopy	retro_etel_1534,
Homo sapiens	ENSG00000184182	2 retrocopies	retro_hsap_2439, retro_hsap_2773,
Gorilla gorilla	ENSGGOG00000010709	3 retrocopies	retro_ggor_1518, retro_ggor_1519, retro_ggor_1930,
Microcebus murinus	ENSMICG00000012075	5 retrocopies	retro_mmur_1014, retro_mmur_114, retro_mmur_1365, retro_mmur_584, retro_mmur_815,
Myotis lucifugus	ENSMLUG00000001286	5 retrocopies	retro_mluc_1237, retro_mluc_1674, retro_mluc_1747, retro_mluc_1789, retro_mluc_2627,
Macaca mulatta	ENSMMUG00000018482	4 retrocopies	retro_mmul_1450, retro_mmul_1585, retro_mmul_254, retro_mmul_628,
Mustela putorius furo	ENSMPUG00000000101	1 retrocopy	retro_mputfur_782,
Mus musculus	ENSMUSG00000034343	3 retrocopies	retro_mmus_2161, retro_mmus_255, retro_mmus_845,
Nomascus leucogenys	ENSNLEG00000011152	2 retrocopies	retro_nleu_1340, retro_nleu_677,
Otolemur garnettii	ENSOGAG00000005308	7 retrocopies	retro_ogar_1109, retro_ogar_1995, retro_ogar_2491, retro_ogar_2551, retro_ogar_2715, retro_ogar_639, retro_ogar_761,
Pongo abelii	ENSPPYG00000013315	3 retrocopies	retro_pabe_1395, retro_pabe_1785 , retro_pabe_2242,
Pan troglodytes	ENSPTRG00000013081	2 retrocopies	retro_ptro_1410, retro_ptro_1876,
Rattus norvegicus	ENSRNOG00000019953	1 retrocopy	retro_rnor_2696,
Sus scrofa	ENSSSCG00000027723	3 retrocopies	retro_sscr_291, retro_sscr_423, retro_sscr_542,
Tarsius syrichta	ENSTSYG00000011510	3 retrocopies	retro_tsyr_1718, retro_tsyr_1944, retro_tsyr_2133,
Tursiops truncatus	ENSTTRG00000011528	2 retrocopies	retro_ttru_1297, retro_ttru_1455,
Vicugna pacos	ENSVPAG00000010485	1 retrocopy	retro_vpac_361,