RetrogeneDB ID: retro_pabe_1868

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 21_random:3882368..3882953(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C1QBP
• Ensembl ID: ENSPPYG00000007870
• Aliases: None
• Description: complement component 1, q subcomponent binding protein [Source:HGNC Symbol;Acc:1243]

Sequence

>retro_pabe_1868
CTGAATGATGAAATTGAGGAGGAAAGGAAAATCCAGAAGCATAAAACCCTCCCTAAGATGTCTGGAGGATGGGAGCGGCA
GTTGAATGGGACAGAAACTAAATTAGTGGGAAAAGTTGCCGGGGAAAGATCGCTGTCACTTTCAACATTAACAACAGCAT
CCCACCGACACTTGATGGTAAGGAGGAACCCTCGAAAGGGCAGCAAGTTGGAGAACAGGAGCCTGAATCGGCATCATCTC
CCAATTTCGTGGTCCAAGTTATAAAGAATGGTGGCAAGAAGGCCCTTGTGCTGGACTGTCACTACCCGGAGGATGAGGGT
GGCCCAGAGGAGGAGGTTGAGAGTGACCTTTTCGCTATCAGGGAAGTAACTTTCAGTCCAGTGGGGAGTCTCAATGAAAG
GACACTAAGTTTATACTCAACGCAGATTCCCTGGACTCGGCCTTATATGACCACCTAATGGATTTCCTTGTGAACGGAGG
GGTGGCCAACCCTTTTGCCGATAAGCTAATGGAGCTCAGCACAGCCCTGGAGGAGCACGAGTACATGATTTTCTTGAAGA
CCTCAGAAGTCCTGTCAAGAGCCAG

Alignment

ORF - retro_pabe_1868 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.88 %
• Parental protein coverage: 69.75 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  LSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRKVAGE-KITVTFNINNSIPPTFDGEEEPSQGQK
          L.DEI.EERKIQKHKTLPKMSGGWE..LNGTE.KLV.KVAGE.KI.VTFNINNSIPPT.DG.EEPS.GQ.
Retrocopy LNDEIEEERKIQKHKTLPKMSGGWERQLNGTETKLVGKVAGE<KIAVTFNINNSIPPTLDGKEEPSKGQQ

Parental  VEEQEPELTSTPNFVVEVIKNDGKKALVLDCHYPEDEVGQEDEAESDIFSIREV-SFQSTGESEWKDTNY
          V.EQEPE..S.PNFVV.VIKN.GKKALVLDCHYPEDE.G.E.E.ESD.F.IREV..FQS.GES..KDT..
Retrocopy VGEQEPESASSPNFVVQVIKNGGKKALVLDCHYPEDEGGPEEEVESDLFAIREV<NFQSSGESQ*KDTKF

Parental  TLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYI-TFLEDLKSFVKSQ
          .LN.DSLD.ALYDHLMDFL...GV.N.FAD.L.ELSTALE..EY...FLEDL.S.VKSQ
Retrocopy ILNADSLDSALYDHLMDFLVNGGVANPFADKLMELSTALEEHEYM<DFLEDLRSPVKSQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	13.60 RPM
SRP007412_cerebellum	0.00 RPM	9.00 RPM
SRP007412_heart	0.00 RPM	11.50 RPM
SRP007412_kidney	0.00 RPM	18.23 RPM
SRP007412_liver	0.00 RPM	13.65 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1868 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1868 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1868 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 55 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000006043	2 retrocopies	retro_amel_1734, retro_amel_356,
Callithrix jacchus	ENSCJAG00000011352	6 retrocopies	retro_cjac_2041, retro_cjac_2408, retro_cjac_4033, retro_cjac_604, retro_cjac_680, retro_cjac_946,
Dasypus novemcinctus	ENSDNOG00000008887	3 retrocopies	retro_dnov_1151, retro_dnov_1946, retro_dnov_702,
Felis catus	ENSFCAG00000026474	3 retrocopies	retro_fcat_1135, retro_fcat_1763, retro_fcat_892,
Homo sapiens	ENSG00000108561	2 retrocopies	retro_hsap_1475, retro_hsap_2516,
Gorilla gorilla	ENSGGOG00000002745	5 retrocopies	retro_ggor_1133, retro_ggor_1569, retro_ggor_3007, retro_ggor_3008, retro_ggor_717,
Macropus eugenii	ENSMEUG00000014882	13 retrocopies	retro_meug_1068, retro_meug_1347, retro_meug_1363, retro_meug_1446, retro_meug_1901, retro_meug_1940, retro_meug_1970, retro_meug_2069, retro_meug_2128, retro_meug_434, retro_meug_580, retro_meug_988, retro_meug_989,
Macaca mulatta	ENSMMUG00000006592	1 retrocopy	retro_mmul_1554,
Nomascus leucogenys	ENSNLEG00000009081	2 retrocopies	retro_nleu_2379, retro_nleu_3038,
Otolemur garnettii	ENSOGAG00000001610	5 retrocopies	retro_ogar_1376, retro_ogar_2502, retro_ogar_2518, retro_ogar_2879, retro_ogar_768,
Ochotona princeps	ENSOPRG00000013150	1 retrocopy	retro_opri_408,
Pongo abelii	ENSPPYG00000007870	6 retrocopies	retro_pabe_1222, retro_pabe_1385, retro_pabe_1413, retro_pabe_1866, retro_pabe_1868 , retro_pabe_670,
Pan troglodytes	ENSPTRG00000008631	3 retrocopies	retro_ptro_1140, retro_ptro_1461, retro_ptro_998,
Pteropus vampyrus	ENSPVAG00000002466	1 retrocopy	retro_pvam_384,
Sarcophilus harrisii	ENSSHAG00000002441	2 retrocopies	retro_shar_620, retro_shar_813,