RetrogeneDB ID:

retro_pabe_2183

Retrocopy
location
Organism:Orangutan (Pongo abelii)
Coordinates:2b_random:344522..346042(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:CDC27
Ensembl ID:ENSPPYG00000008945
Aliases:None
Description:cell division cycle 27 [Source:HGNC Symbol;Acc:1728]


Retrocopy-Parental alignment summary:






>retro_pabe_2183
ATGACAGTGCTGCAGGAACCCTTCCAGGCTGCTATATGGCAAGCACTAAACCACTATGCTTACCGTGATGGGGTTTTCCT
CACAGAACGCCTTTATGCAGAAGTACACTCAGAAGAAGCCTTGTTTTTAATGGCGACCTGTTCTTACCTCCCAGGAAAGG
CCTATAAAGCATATAGACTCTTGAAAAGACACAGTTGTCCTACACCACAATGCAAATACCTGCTTGCAAAATGTTGTGTT
GATCTCAGTAACCTTGCAGACTGGGAACAAATCTTATCTGGTGGAGTGTTTAATAAGCAGAAAAGCCATGATGATATTGT
TACTGAGTTTGGTGATTCAGTTTGCTTTCCCCTTCCATTGTTGGGACGTGTATATTGCAAGACAGATCAGCTTGCCAAAG
GATAAGAATGTTACCAAAAGATACTTAGTTTTAATCCTTTCCTCTGGTATCCCTTTGAATCATTATGTGAAATAGGTGAA
AAGCCAGATCCTGACCAAACATTTAAATTCACATCTTTACAGAACTTTAGCAACTGTCTGCCCAACTCTTGCACAACACA
AGTACCTAATCACAGTTTATGTCACAGACAGCCTGAGACCATTCTTATGGAAACACCCCAGGACACAATTGAATTAAACA
GAGTCAATTTAGAATCTTCCAATTCAAAGTACTCCTTTAATACAGATTCCCCAGTGTCTTTTATTGATTCAGATGTAATT
TCACCTGAAACTATCCCACTGGGAACAGGAACTTCCATATTATCTAAACAGGTTCAAAATAAACCAAAAACTGGTCTAAG
TTTATTAACAGGACCAGCAGCTCTTAGTCCATTTACCCCAAGTTTTGGGATTTTGCCATTAGAAACCCCAAGTCCTGGAG
ATGGATCTTATTTACAAAACTACACTAATACACTTTCTGTAATTGATGTGCCATCCACCGGAGCCCCTTCAAAAAAGTCT
GTTGCCAGAATTGGCCAAACTGGAGCAAAGTCTGTCTTAACGCAGAGTGGAAATAGCCGAGAGGTAACTCCAATTCTTTC
ACTAACAGAAAGTTCTGGTCCATAAATAACTACAACACCTCAGGTAATGAGACCCACTATGACATCTCCCCCAAATGCAC
TGCATCAAAGAAGTTCATGACTCTTTACTAGTGACAGTTCCACACCAAGGAGAATAGGAAGAAATTAAAAATGAAGTTTC
CACCTAAAATCCCAAACAGAAAAACAAAAAGTAAAACTAATAAAGGAGGAATAACTCAATCTAATATAAATGACAACCTG
GAAATTACAAAATTGGACTCTTCCATCAATTCAGAAGAGGAAATATCCACAATCACACCTCAGATTCAGGCTTTTAATCT
ACAAAAAGCAGCAGCAGAAGGCTTGATGAGCCTTCTTCGTGAAAGGGGGAAAGGTTATTTAGCTTTATGTTCATACCACT
GCAATGAAGCTATAAATATTTTGAGCCATCTACCTTCTCACCACTTCAATACTGGTTGGGTACTGTGCCAAATTGGAAGG

ORF - retro_pabe_2183 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 87.4 %
Parental protein coverage: 61.53 %
Number of stop codons detected: 3
Number of frameshifts detected 1


Retrocopy - Parental Gene Alignment:

ParentalMTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEXHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQ
MTVLQEP.QAAIWQALNHYAYRD.VFL.ERLYAE.HSEEALFL.ATC.Y..GKAYKAYRLLK.HSC.TPQ
RetrocopyMTVLQEPFQAAIWQALNHYAYRDGVFLTERLYAEVHSEEALFLMATCSYLPGKAYKAYRLLKRHSCPTPQ
ParentalCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQK
CKYLLAKCCVDLS.LA..EQILSGGVFNKQKSHDDIVTEFGDS.CF.L.LLG.VYCKTD.LAKG.ECYQK
RetrocopyCKYLLAKCCVDLSNLADWEQILSGGVFNKQKSHDDIVTEFGDSVCFPLPLLGRVYCKTDQLAKG*ECYQK
ParentalSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLSHRQPETVLTETPQDTI
.LS.NPFLW.PFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSL.HRQPET.L.ETPQDTI
RetrocopyILSFNPFLWYPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLCHRQPETILMETPQDTI
ParentalELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTP
ELNR.NLESSNSKYS.NTDS.VS.IDS.VISP.T.PLGTGTSILSKQVQNKPKTG.SLL.GPAALSP.TP
RetrocopyELNRVNLESSNSKYSFNTDSPVSFIDSDVISPETIPLGTGTSILSKQVQNKPKTGLSLLTGPAALSPFTP
ParentalSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQSGTKSVFSQSGNSREVTPILAQTQ
SFGILPLETPSPGDGSYLQNYTNT.SVIDVPSTGAPSKKSVARIGQ.G.KSV..QSGNSREVTPIL..T.
RetrocopySFGILPLETPSPGDGSYLQNYTNTLSVIDVPSTGAPSKKSVARIGQTGAKSVLTQSGNSREVTPILSLTE
ParentalSSGPQTSTTPQVLSPTITSPTNALPRRSSRLFTSDSST-TKENSKKLKMKFPPKIPNRKTKSKTNKGGIT
SSGP...TTPQV..PT.TSP.NAL..RSS.LFTSDSST.TKEN.KKLKMKFPPKIPNRKTKSKTNKGGIT
RetrocopySSGP*ITTTPQVMRPTMTSPPNALHQRSS*LFTSDSST<TKENRKKLKMKFPPKIPNRKTKSKTNKGGIT
ParentalQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILS
Q.NIND.LEITKLDSSI.SE..ISTITPQIQAFNLQKAAAEGLMSLLRE.GKGYLALCSY.C.EAINILS
RetrocopyQSNINDNLEITKLDSSINSEEEISTITPQIQAFNLQKAAAEGLMSLLRERGKGYLALCSYHCNEAINILS
ParentalHLPSHHYNTGWVLCQIGR
HLPSHH.NTGWVLCQIGR
RetrocopyHLPSHHFNTGWVLCQIGR

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .00 RPM 43 .24 RPM
SRP007412_cerebellum 0 .00 RPM 52 .05 RPM
SRP007412_heart 0 .00 RPM 16 .95 RPM
SRP007412_kidney 0 .00 RPM 14 .25 RPM
SRP007412_liver 0 .00 RPM 15 .76 RPM
Pongo abelii was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_pabe_2183 retrocopy.
Pongo abelii was not studied using FANTOM5 data.
retro_pabe_2183 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_pabe_2183 has 0 orthologous retrocopies within eutheria group .


Parental genes homology:
Parental genes homology involve 3 parental genes, and 47 retrocopies.

Species Parental gene accession Retrocopies number
Homo sapiens ENSG000000048973 retrocopies
Pongo abelii ENSPPYG00000008945 35 retrocopies
Pan troglodytes ENSPTRG000000093269 retrocopies



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