RetrogeneDB ID:

retro_pabe_2186

Retrocopy
location
Organism:Orangutan (Pongo abelii)
Coordinates:2b_random:911013..912782(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:CDC27
Ensembl ID:ENSPPYG00000008945
Aliases:None
Description:cell division cycle 27 [Source:HGNC Symbol;Acc:1728]


Retrocopy-Parental alignment summary:






>retro_pabe_2186
ATGACAGTGCTGCAGGAACCCGTCCAGGCTGCTATATGGCAAGCACTAAACCACTATGCTTACCGAGATGGGGTTTTCCT
CACAGAAAGCCTTTATGCAGAAGTACACTCAGAAGAAGCCTTGTTTTTAATGGCGACCTGTTCTTACCTCCCAGGAAAGG
CCTATAAAGCATATAGACTCTTGCAAAGACCCAGTTGTCCTACACCACAATGCAAATACCTGCTTGCAAAATGTTGTGTT
GATCTCAGTAAGCTTGCAGACTGGGAACAAATCTTATCTGGTGGAGTGTTTAATAAGCAGAAAAGCCATGATGATATTGT
TACTGAGTTTGGTGATTCAGTTTGCTTTCCCCTTCCATTGTTGGGACGTGTATATTGCAAGACAGATGGGCTTGCTAAAG
GATAAGAATGTTACCAAAAAAGACTTAGTTTAAATCCTTTCCTCTGGTATCCCTTTGAATCATTATGTGAAATAGGTGAA
AAGCCAGATCCTGACCAAACATTTAAATTCACATCTTTACAGAACTTTAGCAACTGTCTGCCCAACTCTTGCACAACACA
AGTACCTAATCACAGTTTATGTCACAGACAGCCTGAGACCATTCTTATGGAAACACCCTAGGACAAAACTGAATTAAACA
GAGTCAATTTAGAATCTTCCAATTCAAAGTACTCCTTGAATACAGATTCCCCAGTGTCTTTTATTGATTCAGCTGTAATT
TCACCTGAAACTGTCCCACTGGGAACAGGAACTTCCATATTATCTAAACAGGTTCAAAATAAACCAAAAACTGGTCGAAG
TTTATTAACAAGACCAACAGCTCTTAGTCCATTTACCCCAAGTTTTGGGATTTTGCCATTAGAAACCCCAAGTCCTGGAG
ATGGATCTTATTTACAAAACTACACTAATACACCTTCTGTAATTGATGTGCCATCCACCGGAGCCCCTTCAAAAAAGTCT
GTTGCCAGAATTGGCCAAACTGGAGCAAAGTCTATCTTCTCGCAGAGTGGAAATAGCCGAGAGGTAACTCCAATTCTTTC
ACTAACAGAAAGTTCTGGTCCATAAATAACTACAACACCTCAGGTAATGAGCCCCACTATGACATCTCCCCCAAATGCAC
TGCATCGAAGAAGTTCATGACTCTTTACTAGTGACAGTTCCACAACCAAGGAGAATAGGAAGAAATTAAAAATGAAGTTT
CCACCTAAAATCCCAAACAGAAAAACAAAAAGTAAAACTAATAAAGGAGGAATAACTCAATCTAATATAAATGACAACCT
GGAAATTACAAAATTGGACTCTTCCATCAATTCAGAAGAGGAAATATCCACAATCACACCTCAGATTCAGGCTTTTAATC
TACAAAAAGCAGCAGCAGAAGGCTTGATGAGCCTTCTTCATGAAAGGGGGAAAGGTTATTTAGCTTTATGTTCATACCAC
TGCAAAGAAGCTATAAATATTTTGAGCCATCTACGTTCTCACCACTACAATACTGGTTGGGTACTGTGCCAAATTGGAAG
GTCCTATTTTGAACTTTCAGAGTACATGCAAGCTGAAAGAATATTCTCAGAGGTTAGAAGATTGAGAATTATAGAGTCGA
AGCATGGAAATCTACACACTTTGGCATATTCAAAAAGATGTCACTCTTTCATTTCTGTCAAAAGACTTAACAGACATGGA
TAAAATTCGTCAGACGCCTGTGTGCTGCAAGGAACTGTTTCAGTCTGCACAAGGAACACGATATTGCAATTAAATTCTTC
CAGAGATCC

ORF - retro_pabe_2186 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 86.93 %
Parental protein coverage: 71.97 %
Number of stop codons detected: 4
Number of frameshifts detected 4


Retrocopy - Parental Gene Alignment:

ParentalMTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEXHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQ
MTVLQEPVQAAIWQALNHYAYRD.VFL.E.LYAE.HSEEALFL.ATC.Y..GKAYKAYRLL...SC.TPQ
RetrocopyMTVLQEPVQAAIWQALNHYAYRDGVFLTESLYAEVHSEEALFLMATCSYLPGKAYKAYRLLQRPSCPTPQ
ParentalCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQK
CKYLLAKCCVDLSKLA..EQILSGGVFNKQKSHDDIVTEFGDS.CF.L.LLG.VYCKTD.LAKG.ECYQK
RetrocopyCKYLLAKCCVDLSKLADWEQILSGGVFNKQKSHDDIVTEFGDSVCFPLPLLGRVYCKTDGLAKG*ECYQK
ParentalSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLSHRQPETVLTETPQDTI
.LSLNPFLW.PFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSL.HRQPET.L.ETP.D..
RetrocopyRLSLNPFLWYPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLCHRQPETILMETP*DKT
ParentalELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTP
ELNR.NLESSNSKYSLNTDS.VS.IDSAVISP.TVPLGTGTSILSKQVQNKPKTGRSLL..P.ALSP.TP
RetrocopyELNRVNLESSNSKYSLNTDSPVSFIDSAVISPETVPLGTGTSILSKQVQNKPKTGRSLLTRPTALSPFTP
ParentalSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQSGTKSVFSQSGNSREVTPILAQTQ
SFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQ.G.KS.FSQSGNSREVTPIL..T.
RetrocopySFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQTGAKSIFSQSGNSREVTPILSLTE
ParentalSSGPQTSTTPQVLSPTITSPTNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ
SSGP...TTPQV.SPT.TSP.NAL.RRSS.LFTSDSSTTKEN.KKLKMKFPPKIPNRKTKSKTNKGGITQ
RetrocopySSGP*ITTTPQVMSPTMTSPPNALHRRSS*LFTSDSSTTKENRKKLKMKFPPKIPNRKTKSKTNKGGITQ
ParentalPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSH
.NIND.LEITKLDSSI.SE..ISTITPQIQAFNLQKAAAEGLMSLL.E.GKGYLALCSY.CKEAINILSH
RetrocopySNINDNLEITKLDSSINSEEEISTITPQIQAFNLQKAAAEGLMSLLHERGKGYLALCSYHCKEAINILSH
ParentalLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR-IENYRVE-GMEIYSTTLWHLQKDVALSVLSKD
L.SHHYNTGWVLCQIGR.YFELSEYMQAERIFSEVRR.IENYRVE..MEIY..TLWH.QKDV.LS.LSKD
RetrocopyLRSHHYNTGWVLCQIGRSYFELSEYMQAERIFSEVRR<IENYRVE<SMEIY--TLWHIQKDVTLSFLSKD
ParentalLTDMDK-NSPEA-WCAAGNCFSLQREHDIAIKFFQRA
LTDMDK.NS..A..CAA.NCFSL..EHDIAIKFFQR.
RetrocopyLTDMDK<NSSDA<LCAARNCFSLHKEHDIAIKFFQRS

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .00 RPM 43 .24 RPM
SRP007412_cerebellum 0 .00 RPM 52 .05 RPM
SRP007412_heart 0 .00 RPM 16 .95 RPM
SRP007412_kidney 0 .00 RPM 14 .25 RPM
SRP007412_liver 0 .00 RPM 15 .76 RPM

ChIP-Seq - click to see more details

Pongo abelii was not studied using ChIP-Seq data.

EST - click to see more details

No EST(s) were mapped for retro_pabe_2186 retrocopy.

TSS - click to see more details

Pongo abelii was not studied using FANTOM5 data.

Lab - click to see more details

retro_pabe_2186 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_pabe_2186 has 0 orthologous retrocopies within eutheria group .

Parental genes homology:
Parental genes homology involve 3 parental genes, and 47 retrocopies.

Species Parental gene accession Retrocopies number
Homo sapiens ENSG000000048973 retrocopies
retro_hsap_2159, retro_hsap_4333, retro_hsap_4933,
Pongo abelii ENSPPYG00000008945 35 retrocopies
retro_pabe_2094, retro_pabe_2169, retro_pabe_2170, retro_pabe_2172, retro_pabe_2178, retro_pabe_2182, retro_pabe_2183, retro_pabe_2184, retro_pabe_2185, retro_pabe_2186 , retro_pabe_2190, retro_pabe_2192, retro_pabe_3526, retro_pabe_3545, retro_pabe_3547, retro_pabe_3550, retro_pabe_3551, retro_pabe_3553, retro_pabe_3556, retro_pabe_3582, retro_pabe_3583, retro_pabe_3589, retro_pabe_3592, retro_pabe_3598, retro_pabe_3599, retro_pabe_3603, retro_pabe_3605, retro_pabe_3606, retro_pabe_3607, retro_pabe_3609, retro_pabe_3610, retro_pabe_3827, retro_pabe_3828, retro_pabe_3833, retro_pabe_3834,
Pan troglodytes ENSPTRG000000093269 retrocopies
retro_ptro_1644, retro_ptro_2972, retro_ptro_3053, retro_ptro_3071, retro_ptro_3072, retro_ptro_3288, retro_ptro_3294, retro_ptro_3295, retro_ptro_3304,


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