RetrogeneDB ID:

retro_pabe_3609

Retrocopy
location
Organism:Orangutan (Pongo abelii)
Coordinates:Un:67600490..67602250(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:CDC27
Ensembl ID:ENSPPYG00000008945
Aliases:None
Description:cell division cycle 27 [Source:HGNC Symbol;Acc:1728]


Retrocopy-Parental alignment summary:






>retro_pabe_3609
GGAAAGGCCCTAATAAAGGCATATAGACTCTTGAAAAGACACAGTTGTCCTACACCACAATGCAAATACTGCTTGCAAAA
TGTTGTGTTGATCTCAGTAAGCTTGCAGACTGGGAACAAATCTTATCTGGTGGAGTGTTTAATAAGCAGAAAAGCCATGA
TGATATTGTTACTGAGTTTGGTGATTCAGTTTGCTTTCCCCTTCCATTGTTGGGATGTGTATATTGCAAGACAGATCGGC
TTGCCAAAGGATAAGAATGTTACCAAAAGAGACTTAGTTTAAATCCTTTCCTCTGGTATCCCTTTGAATCATTATGTGAA
ATAGGTGAAAAGCCAGATCCAGACCAAACATTTAAATTCACATCTTTACAGAACTTTAGAAACTGTCTGCCCAACTCTTG
CACAACACAAGTACCTAATCACAGTTTTTGTCACAGACAGCCTGAGACCATTCTTATGGAAACACCCCAGGGCACAATTG
AATTAAACAGAGTCAATTTAGAATCTTTCAATTCAAAGTACTCCTTGAATACGGATTCCCCAGTGTCTTTTATTGATTCA
GCTGTAATTTCACCTGAAACTATCCCACTGGGAACAGGAACTTCCATATTATCTAAACAGGTTCAAAATAAACCAAAAAC
TGGTCAAAGTTTATTAACAGGACCAGCAGCTCTTAGTCCATTTACCCCAAGTTTTGGGATTTTGCCATTAGAAACCCCAA
GTCCTGGAGATGGATCTTATTTACAAAACTACACTAATACACCTTCTGTAATTGATGTGCCATCCACTGGAGCCCCTTCA
AAAAAGTCTGTTGCCAGAATTGGCCAAACTGGAGCAAAGTCTGTCTTCTCACAGAGTGGAAATAGCCGAGAGGTAACTAC
AATTCTTTCACTAACAGAAAGTTCTGGTCCATAAATAACTACAACACCTCAGGTAATGAGCCCCACTATGACATCTCCCC
CAAATGCACGGCATCGAAGAAGTTCATGACTCTTTACTAGTGACAGTTCCACAACCAAGGAGAATAGGAAGAAATTAAAA
ATGAAGTTTCCACCTAAAATCCCAAACAGAAAAACAAAAAGTAAAACAAATAAAGGAGGAATAACTCAATCTAATATAAA
TGACAACCTGGAAATTACAAAATTGGACTCTTCCATCAATTCAGAAGAGGAAATATCCACAATCACACCTCAGATTCAGG
CTTTTCATCTACAAAAAGCAGCAGCAGAAGGCTTGATGAGCCTTCTTCTGAAAGGGGGAAAGGTTATTTAGATTTATGTT
CATACCACTGCAAAGAAGCTATAAATATTTTGAGCCATCTACCTTCTCACCACTTCAATACTGGTTGGGTACTTTGCCAA
ATTGGAAGGTCCTATTTTGACCTTTCAGAGTACATGCAAGCTGAAAGAATATTCTCAGAGGTTAGAAGGATTGAGAATTA
TAGAGTCGAAGGCATGGAAATCTACTCTACAACACTTTGGCATCTTCAAAAAGATGTCGCTCTTTCATTTCTGTCAAAAG
ACTTAACAGACACGGATAAAAATTCGCCAGAGGCCTGGTGTGCTGCAGGGAACTGTTTCAGTCTGCAACAGGAACACGAT
ATTGCAATTAAATTCTTCCAGAGAGCTATCCAAGTGGATCCAAATTATGCTTATGCCTATACTTTATTAGGGCGAGAGTT
TGTCTTAACTGAAGAATTGGACAAGCATTAGCTTGTATTCAAAATGCTATCAGAGTCAGTCCTAGACATTACATGCATGG

ORF - retro_pabe_3609 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 85.98 %
Parental protein coverage: 71.24 %
Number of stop codons detected: 3
Number of frameshifts detected 4


Retrocopy - Parental Gene Alignment:

ParentalGKAY-KAYRLLKGHSCTTPQCKY-LLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLS
GKA..KAYRLLK.HSC.TPQCKY.LLAKCCVDLSKLA..EQILSGGVFNKQKSHDDIVTEFGDS.CF.L.
RetrocopyGKALIKAYRLLKRHSCPTPQCKY<LLAKCCVDLSKLADWEQILSGGVFNKQKSHDDIVTEFGDSVCFPLP
ParentalLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVP
LLG.VYCKTDRLAKG.ECYQK.LSLNPFLW.PFESLCEIGEKPDPDQTFKFTSLQNF.NCLPNSCTTQVP
RetrocopyLLGCVYCKTDRLAKG*ECYQKRLSLNPFLWYPFESLCEIGEKPDPDQTFKFTSLQNFRNCLPNSCTTQVP
ParentalNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQ
NHS..HRQPET.L.ETPQ.TIELNR.NLES.NSKYSLNTDS.VS.IDSAVISP.T.PLGTGTSILSKQVQ
RetrocopyNHSFCHRQPETILMETPQGTIELNRVNLESFNSKYSLNTDSPVSFIDSAVISPETIPLGTGTSILSKQVQ
ParentalNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQSGT
NKPKTG.SLL.GPAALSP.TPSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQ.G.
RetrocopyNKPKTGQSLLTGPAALSPFTPSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPSKKSVARIGQTGA
ParentalKSVFSQSGNSREVTPILAQTQSSGPQTSTTPQVLSPTITSPTNALPRRSSRLFTSDSSTTKENSKKLKMK
KSVFSQSGNSREVT.IL..T.SSGP...TTPQV.SPT.TSP.NA..RRSS.LFTSDSSTTKEN.KKLKMK
RetrocopyKSVFSQSGNSREVTTILSLTESSGP*ITTTPQVMSPTMTSPPNARHRRSS*LFTSDSSTTKENRKKLKMK
ParentalFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLL-RE
FPP..............GITQ.NIND.LEITKLDSSI.SE..ISTITPQIQAF.LQKAAAEGLMSLL..E
RetrocopyFPPXXXXXXXXXXXXXXGITQSNINDNLEITKLDSSINSEEEISTITPQIQAFHLQKAAAEGLMSLL<SE
ParentalMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEI
.GKGYL.LCSY.CKEAINILSHLPSHH.NTGWVLCQIGR.YF.LSEYMQAERIFSEVRRIENYRVEGMEI
RetrocopyRGKGYLDLCSYHCKEAINILSHLPSHHFNTGWVLCQIGRSYFDLSEYMQAERIFSEVRRIENYRVEGMEI
ParentalYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG
YSTTLWHLQKDVALS.LSKDLTD.DKNSPEAWCAAGNCFSLQ.EHDIAIKFFQRAIQVDPNYAYAYTLLG
RetrocopyYSTTLWHLQKDVALSFLSKDLTDTDKNSPEAWCAAGNCFSLQQEHDIAIKFFQRAIQVDPNYAYAYTLLG
ParentalHEFVLTEELDK-ALACFRNAIRVNPRHY-NAW
.EFVLTEELDK.ALAC..NAIRV.PRHY..AW
RetrocopyREFVLTEELDK<ALACIQNAIRVSPRHY<HAW

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .00 RPM 43 .24 RPM
SRP007412_cerebellum 0 .00 RPM 52 .05 RPM
SRP007412_heart 0 .00 RPM 16 .95 RPM
SRP007412_kidney 0 .00 RPM 14 .25 RPM
SRP007412_liver 0 .00 RPM 15 .76 RPM
Pongo abelii was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_pabe_3609 retrocopy.
Pongo abelii was not studied using FANTOM5 data.
retro_pabe_3609 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_pabe_3609 has 0 orthologous retrocopies within eutheria group .


Parental genes homology:
Parental genes homology involve 3 parental genes, and 47 retrocopies.

Species Parental gene accession Retrocopies number
Homo sapiens ENSG000000048973 retrocopies
Pongo abelii ENSPPYG00000008945 35 retrocopies
Pan troglodytes ENSPTRG000000093269 retrocopies



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