RetrogeneDB ID: retro_ptro_378

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 1:191979716..191979906(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS28
• Ensembl ID: ENSPTRG00000040141
• Aliases: None
• Description: ribosomal protein S28 [Source:HGNC Symbol;Acc:10418]

Sequence

>retro_ptro_378
GACACCAGCCATGTGCAGCCTATCTAGCTAGCCAGGGTCACCAAGGTCCTGGGCAGAACCAGCTCTCAGGGACAGTGCAT
GCGGGAATTTATAGACACAAGCCACTCCATCATCCACAGTGTGAAAGGCCCCATGCGCAAGGGCTATGTGCTCACCCTGT
TTGGAGTCAGAGCGAGAGGCCTGGAGGTTG

Alignment

ORF - retro_ptro_378 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.53 %
• Parental protein coverage: 97.1 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  DTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTL-LESEREARRL
          DTS.VQPI.LARVTKVLGRT.SQGQC.....EF..DTS.SII..VKGP.R.G.VLTL.LESEREA.RL
Retrocopy DTSHVQPI*LARVTKVLGRTSSQGQCMR---EFI-DTSHSIIHSVKGPMRKGYVLTL>LESEREAWRL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.02 RPM	177.49 RPM
SRP007412_cerebellum	0.00 RPM	71.02 RPM
SRP007412_heart	0.00 RPM	67.79 RPM
SRP007412_kidney	0.00 RPM	248.76 RPM
SRP007412_liver	0.00 RPM	135.03 RPM
SRP007412_testis	0.00 RPM	11.07 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_378 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_378 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_378 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_505

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 26 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000233927	9 retrocopies	retro_hsap_1192, retro_hsap_1352, retro_hsap_1725, retro_hsap_2220, retro_hsap_2279, retro_hsap_3748, retro_hsap_505, retro_hsap_523, retro_hsap_799,
Loxodonta africana	ENSLAFG00000029923	2 retrocopies	retro_lafr_168, retro_lafr_755,
Macaca mulatta	ENSMMUG00000028895	3 retrocopies	retro_mmul_122, retro_mmul_182, retro_mmul_807,
Monodelphis domestica	ENSMODG00000003890	1 retrocopy	retro_mdom_291,
Mus musculus	ENSMUSG00000067288	3 retrocopies	retro_mmus_2949, retro_mmus_3283, retro_mmus_91,
Pan troglodytes	ENSPTRG00000040141	6 retrocopies	retro_ptro_1228, retro_ptro_1613, retro_ptro_3037, retro_ptro_378 , retro_ptro_391, retro_ptro_927,
Rattus norvegicus	ENSRNOG00000042886	2 retrocopies	retro_rnor_95, retro_rnor_96,