RetrogeneDB ID: retro_ptro_888

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 13:101017340..101017803(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ARF4
• Ensembl ID: ENSPTRG00000015051
• Aliases: None
• Description: None

Sequence

>retro_ptro_888
GGCCTCACCATCTCCTCTTTCTTCTCCCACCTCTTTGACAAGAAGCAGATGCACATTTTGATGGTTGGATTGGATGCCGC
TGGCAAGACGACCATTCCGTATGAACTGAAGTTAGGGGAGATAGTCACCACCATTCCTACCATTGGCTGCAATGTGGAAG
CGGTTGACTATAAAAACATTCGTTTCACAGTATGGGATGCCGGTGGTCAAGATAGAATTAGGCCTCTCCGGAAGTATTAC
TTCCCAAATACCCAATATCTTATATTTGTGGTAGATAGCAATAATCGTGAAAGAATTAAGGAGGTAGCAGGTGAGCTGCA
GAAATTGCTTCTGGTAGATGAGTTGAGAGAGGCAGTGCTGCTGCTTTTTGAGAATCACAGGATTTGCCAAATGCTCTTCG
ATCTCCTCCTAACAGGACATGATCTGTTCAAGCCACGTGCATAACACAAGGAACTGGTCTGTG

Alignment

ORF - retro_ptro_888 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.52 %
• Parental protein coverage: 85.56 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  GLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQ
          GLTISS.FS.LF.KKQM.ILMVGLDAAGKTTI.Y.LKLGEIVTTIPTIG.NVE.V.YKNI.FTVWD.GGQ
Retrocopy GLTISSFFSHLFDKKQMHILMVGLDAAGKTTIPYELKLGEIVTTIPTIGCNVEAVDYKNIRFTVWDAGGQ

Parental  DRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFAN-KQDLPNAM-AISEM
          DRIRPL.K.YF.NTQ.LIFVVDSN.RERI.EVA.ELQK.LLVDELR.AVLLLF.N..QDLPNA...IS..
Retrocopy DRIRPLRKYYFPNTQYLIFVVDSNNRERIKEVAGELQKLLLVDELREAVLLLFEN<SQDLPNAL<SISS*

Parental  TDKLGLQSLRN-RTWYV
          .D........N.R.W.V
Retrocopy QDMICSSHVHNTRNWSV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	32.80 RPM
SRP007412_cerebellum	0.00 RPM	36.03 RPM
SRP007412_heart	0.00 RPM	34.28 RPM
SRP007412_kidney	0.00 RPM	61.56 RPM
SRP007412_liver	0.00 RPM	98.04 RPM
SRP007412_testis	0.11 RPM	60.07 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_888 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_888 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_888 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1296
Gorilla gorilla	retro_ggor_1016
Pongo abelii	retro_pabe_1075
Callithrix jacchus	retro_cjac_507

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 45 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000016069	1 retrocopy	retro_btau_542,
Choloepus hoffmanni	ENSCHOG00000006427	4 retrocopies	retro_chof_1024, retro_chof_1807, retro_chof_2368, retro_chof_36,
Ciona intestinalis	ENSCING00000021790	1 retrocopy	retro_cint_10,
Callithrix jacchus	ENSCJAG00000019922	1 retrocopy	retro_cjac_507,
Cavia porcellus	ENSCPOG00000010334	1 retrocopy	retro_cpor_1261,
Dipodomys ordii	ENSDORG00000004312	1 retrocopy	retro_dord_731,
Homo sapiens	ENSG00000168374	2 retrocopies	retro_hsap_1296, retro_hsap_4221,
Gorilla gorilla	ENSGGOG00000000294	1 retrocopy	retro_ggor_1552,
Microcebus murinus	ENSMICG00000002015	3 retrocopies	retro_mmur_1528, retro_mmur_1558, retro_mmur_360,
Myotis lucifugus	ENSMLUG00000007990	1 retrocopy	retro_mluc_2272,
Macaca mulatta	ENSMMUG00000018617	1 retrocopy	retro_mmul_50,
Monodelphis domestica	ENSMODG00000000185	1 retrocopy	retro_mdom_1538,
Nomascus leucogenys	ENSNLEG00000007270	3 retrocopies	retro_nleu_2106, retro_nleu_2703, retro_nleu_2704,
Oryctolagus cuniculus	ENSOCUG00000000824	4 retrocopies	retro_ocun_1007, retro_ocun_1502, retro_ocun_1868, retro_ocun_987,
Otolemur garnettii	ENSOGAG00000012034	4 retrocopies	retro_ogar_1407, retro_ogar_1501, retro_ogar_2963, retro_ogar_764,
Pongo abelii	ENSPPYG00000013768	3 retrocopies	retro_pabe_1013, retro_pabe_1075, retro_pabe_3451,
Pan troglodytes	ENSPTRG00000002066	2 retrocopies	retro_ptro_112, retro_ptro_5,
Pan troglodytes	ENSPTRG00000015051	2 retrocopies	retro_ptro_2866, retro_ptro_888 ,
Rattus norvegicus	ENSRNOG00000012623	2 retrocopies	retro_rnor_1036, retro_rnor_1884,
Sorex araneus	ENSSARG00000009272	1 retrocopy	retro_sara_681,
Ictidomys tridecemlineatus	ENSSTOG00000019470	2 retrocopies	retro_itri_1439, retro_itri_1614,
Tupaia belangeri	ENSTBEG00000007415	1 retrocopy	retro_tbel_2075,
Tarsius syrichta	ENSTSYG00000009748	1 retrocopy	retro_tsyr_2059,
Tursiops truncatus	ENSTTRG00000015381	1 retrocopy	retro_ttru_284,
Vicugna pacos	ENSVPAG00000003891	1 retrocopy	retro_vpac_459,