RetrogeneDB ID: retro_rnor_412

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 7:15650915..15653975(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSRNOG00000004501
• Aliases: Morc2b, RGD1564020
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: Morc2
• Ensembl ID: ENSRNOG00000019624
• Aliases: Morc2, Morc2a, Zcwcc1
• Description: MORC family CW-type zinc finger 2 [Source:RefSeq peptide;Acc:NP_001099486]

Sequence

>retro_rnor_412
ATGGCATTCACCAATTACAGCAGCCTCAACCGGGCTCAACTAACCTTTGAATATCTACACACAAACTCAACTACCCATGA
ATTTTTGTTTGGTGCTCTTGCTGAACTGGTTGATAACTCGAGAGATGCTGATGCCACCCGGATAGATATTTATGCTGAAA
GGCGAGAGGACCTTCAAGGAGGGTTCATGCTTTGTTTTCTGGATAATGGAGCAGGAATGGATCCAAATGATGCCATCAGT
GTAATCCAATTTGGGAAATCAGCCAAACGAACACCAGAGTCCACACAGATTGGGCGGTACGGGAATGGGCTAAAATCAGG
CTCAATGCGTATTGGAAAGGATTTTATCCTCTTCACGAAGAAGGAAGACACCATGAGCTGCCTCTTCCTGTCTCGGACCT
TTCATGAGGAAGAAGGCATTGACGAAGTGATAGTCCCTTTGCCTACTTGGAGTGCTCATACACGAGAACCTGTCACAGAC
AATGTGGAGAAGTTTGCCATCGAGACAGAACTCATCTACAAGTATTCTCCTTTCCACACTGAGGAAGAAGTGATGAACCA
GTTCACCAAGATTTCTGGGACCAGTGGAACCCTGGTGATCATTTTCAACCTCAAACTCATGGACAATGGGGAACCCGAAC
TAGACATAACCTCAAATCCAAAAGATATCCGGATGGCAGAGATCTCCCAGGAAGGCACGAAGCCAGAGCGGCACTCCTTC
TGCGCCTACGCGGCTGTGCTTTACATTGATCCTCGGATGAGGATTTTTATTCAAGGGCACAAGGTGCAGACCAAAAAGCT
CTCCTGCTGCTTGTACAAGCCCAGGAAGTACACATTCACATCAAGCCGTTTTAAGACCAGGGCGGAACAAGAGGTGAAGA
AAGCAGACCAGGTAGCACGGCTTGCCGAAGAGAAGGCCCGGGAAGCAGAGAGCAAATCTCATACTTTAGAAGTGCACATA
GGCGGAGACATCACCCGGGACTCGAGGGCGATGTTGCGCCAGGTCCAGAATACAGCCATCACCCTCCGAAGAGAAGCTGA
CGTCAAGAAAAGGATCCGAGACGCCAAAGAGCGAGCACTCAAAGAGCCCAAGGAACTGAATTTCGTTTTCGGGGTCAACA
TTGAACGCCGTGACCACGACGGCATGTTCATCTACAACTGTAGCCGCCTGATCAAGATGTATGAGAAAGTGGGCCCACAG
CTGGAAAAGGGGATGGCATGCGGTGGGGTTGTTGGAGTCATCGATGTGCCCTACTTGGTCCTAGAACCTACGCACAGCAA
GCAGGACTTTGCTGACGCCAAGGAGTACCGTCTGCTGCTGCGGGCAATGGGCGAGCACCTGGCACAGTACTGGAAGGACA
TCGCCATTACCCAGTACGGAATTATTAAGTTCTGGGATGAGTTTGGCTACCTTTCAGCTAACTGGAACAGACCTCCATCT
GAGGAGCTGCATTTCAAACGCAAGAGAGCTATGCAAGTCCCAACCACCATACAGTGTGATTTGTGTCTAAAGTGGAGAAC
CCTCCCCTTCCAGTTAAGTGCTGTAGAAGAAGGCTACCCAGACAACTGGGTTTGTTCCATGAACCCTGATCCTGAACAGG
ACCAGTGCGAGGCTTTTGAACAGACGCAGAAGATTCCTCTGGGGACATTAAAAAAGGTCCCAAAGACACAAGAAGAAAGG
CAGAAGCAGCTGACAGAGAAAATTCGCCAACATCAGAGGAAGCTTAAGGCCCTTAAGAAAATCAAGCCTATCCATTCCCA
AAGTGACCTGAAAAAATTACCCTGGGAAGTGACCACCAGACCTTCCTCCAAATATCCTGCTCATAGATTTCAGGGTCCTC
AACCATCTTCACGTGCTGTGAAAAAGAGTGCCCGAAGAAGACTCCAGTCCAGGCATGCTCCTAGGCCATTCAGACAGCTC
CAAAGGTCTTCTATCTTCTGCACCAACCCAAAATCTCCTGTTCTGGCAGACCAAACAGAAGTCATGCTGCTCCAGCCACC
TGAGACACCCCAAAGCCCAGTGAGCCCAGTGGCCAAAACTCTACCCAAGCCCACCCCCCTGTTACAATCCCTGTCCCCAT
CTGTAGTCCCCAACTCCAACAACCTTTGGAAGGTTGGAACCCCCAAAGCCATGAACGCTCCAGTGGCTGAGATGCCGGAT
CCACCTGTTAATCCCTCACTGGTAAAGTGCGGTCGTAAGCGGAGTCTTGAGGTCTCTGATAAGGACAGGAGGAAGATGTG
CAAACGGGGCAGGTTTGCCCAGAAAAAAGAAAAGATTCAAGCGAATGAGCTCTCAGACAGTGCCGAGGAGGAGAGTTCAG
CTGACCTCAAGACGGCTCAGAAAGATAAAGGGCTGTACGTGGAGGTACGTGTGAAAGGAGAGTGCTACAAGGGCCACGTC
ACAGCTGTGGAGGTGGGTGATAATGTGGTATGGTGGAAGGTCAAGTTTGAGGATGTGCCCAAGGATAGCACACCAAGAGA
CTGCTGGGTGGAAAAAGGCAGTGAAAATGTATGGCTAATGAAGCCATCTCCAGAGTATCAGAGTACTGACGAACAGCAAG
AGGATATAAGTAGGGAAGAGAACACTGTGGTCCAGCAGGCTTTGGCACTGCAGAGGGCCTCCATCTCTGAATGCTTCTGC
ACAGAACCTGACACTACTGCCCCAACGGCCAACCACAAGACCATTGACCTCCTGGTCCAAATTCTCTGGAATTGCTTGCG
TTATTTCATGCCCCTGAGTTTCCCCATATCCAAGAAGGAGCTAGGTGCTATGAATTCAGAAGAATTACTCTCTCTCCCTC
TGAAAGAGTGCTTCAAGCAATATGAAGTCGGACTCCAGAACCTCTGCCACTCCTACGAAAGCTGTGCCGACTCACAAGCC
AAGGCCTCTGAGGAAAGCCTGCGCATCTCCCAGAAAAAACTCCAGGAAACAGAGGAGAAACTCCAGAAGCTGCGGACCAA
TATTCGGGCACTCTTGCAAAAGGCTCAGGAGGACATAAACATCAGCGCAGATGACGAGCTGGATGCCTACATTGAGAATC
TGGTCAGCGGTGATGACTGA

Alignment

ORF - retro_rnor_412 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.97 %
• Parental protein coverage: 74.01 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  ERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE
          ERREDL.GGFMLCFLD.GAGMDP.DA.SVIQFGKSAKRTPESTQIG.YGNGLKSGSMRIGKDFILFTKKE
Retrocopy ERREDLQGGFMLCFLDNGAGMDPNDAISVIQFGKSAKRTPESTQIGRYGNGLKSGSMRIGKDFILFTKKE

Parental  DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPITDNVEKFAIETELVYKYSPFHTEEQVMNQFMKIP
          DTM.CLFLSRTFHEEEGIDEVIVPLPTW.A.TREP.TDNVEKFAIETEL.YKYSPFHTEE.VMNQF.KI.
Retrocopy DTMSCLFLSRTFHEEEGIDEVIVPLPTWSAHTREPVTDNVEKFAIETELIYKYSPFHTEEEVMNQFTKIS

Parental  GNSGTLVIIFNLKLMDNGEPELDIISNPKDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKV
          G.SGTLVIIFNLKLMDNGEPELDI.SNPKDI.MAE.S.EGTKPER.SF.AYAAVLYIDPRMRIFI.GHKV
Retrocopy GTSGTLVIIFNLKLMDNGEPELDITSNPKDIRMAEISQEGTKPERHSFCAYAAVLYIDPRMRIFIQGHKV

Parental  QTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRMGGDLTRDSRVML
          QTK.LSCCLYKPR.Y..TSSRFKTRAEQEVKKA..VAR.AEEKAREAESK..TLEV..GGD.TRDSR.ML
Retrocopy QTKKLSCCLYKPRKYTFTSSRFKTRAEQEVKKADQVARLAEEKAREAESKSHTLEVHIGGDITRDSRAML

Parental  RQVQNAAITLRREADVKKRIKDAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLE
          RQVQN.AITLRREADVKKRI.DAK.RALKEPKELNFVFGVNIE.RD.DGMFIYNCSRLIKMYEKVGPQLE
Retrocopy RQVQNTAITLRREADVKKRIRDAKERALKEPKELNFVFGVNIERRDHDGMFIYNCSRLIKMYEKVGPQLE

Parental  GGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLS
          .GMACGGVVGV.DVPYLVLEPTH.KQDFADAKEYR.LLRAMGEHLAQYWKDIAI.Q.GIIKFWDEFGYLS
Retrocopy KGMACGGVVGVIDVPYLVLEPTHSKQDFADAKEYRLLLRAMGEHLAQYWKDIAITQYGIIKFWDEFGYLS

Parental  ANWNQPPSSELRFKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQK
          ANWN.PPS.EL.FKR.RAM..PTTIQCDLCLKWRTLPFQLS.VE..YPD.WVCSMNPDPEQD.CEA.EQ.
Retrocopy ANWNRPPSEELHFKRKRAMQVPTTIQCDLCLKWRTLPFQLSAVEEGYPDNWVCSMNPDPEQDQCEAFEQT

Parental  QKVPLGTLKKDPKSQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQR
          QK.PLGTLKK.PK.QEE.QKQLTEKIRQ.Q.KL.AL.K..PI.SQ.DLKKLP.EVTTRPS...P..R.Q.
Retrocopy QKIPLGTLKKVPKTQEERQKQLTEKIRQHQRKLKALKKIKPIHSQSDLKKLPWEVTTRPSSKYPAHRFQG

Parental  PRSPPLPAVIKNAPSRPPSIQTPRPATQLRKTSVI-SSPKPPATAARGETSTSRILQPAEAPRKPANLPI
          P..P...AV.K.A..R..S...PRP..QL...S.....PK.P..A...E......LQP.E.P..P.....
Retrocopy PQ-PSSRAVKKSARRRLQSRHAPRPFRQLQRSSIFCTNPKSPVLADQTEV---MLLQPPETPQSPVSPVA

Parental  KTVPRPTPTVQTPSPSLIPNSKNLREVPAQKAIKTPMVKKPEPPAKQSMASSGRKRSLVVSDEEEAEEEA
          KT.P.PTP..Q..SPS..PNS.NL..V...KA...P....P.PP...S....GRKRSL.VSD........
Retrocopy KTLPKPTPLLQSLSPSVVPNSNNLWKVGTPKAMNAPVAEMPDPPVNPSLVKCGRKRSLEVSDKDR-RKMC

Parental  EKRKERCKRGKLAVKEEKKEANELSDS
          .......K..K....E....A.E.S..
Retrocopy KRGRFAQKKEKIQANELSDSAEEESSA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	40.33 RPM
SRP017611_kidney	0.00 RPM	31.33 RPM
SRP017611_liver	0.00 RPM	10.09 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_412 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_412 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_412 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Cavia porcellus	ENSCPOG00000006442	1 retrocopy	retro_cpor_17,
Monodelphis domestica	ENSMODG00000009557	1 retrocopy	retro_mdom_1757,
Mus musculus	ENSMUSG00000034543	1 retrocopy	retro_mmus_49,
Otolemur garnettii	ENSOGAG00000009971	2 retrocopies	retro_ogar_2044, retro_ogar_282,
Rattus norvegicus	ENSRNOG00000019624	1 retrocopy	retro_rnor_412 ,