RetrogeneDB ID: retro_cfam_1322

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 3:1626646..1627342(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000012109
• Aliases: PRDX3, AOP1
• Description: None

Sequence

>retro_cfam_1322
GCTTCTGCAGCCCTAGCCCTGCTGCTTTCCAAAGAACATGGCTGACAAATGTATTATGGTCTGGTTCCGGTCAAACAAAA
TTCACTTTTCGCACCAATTGCTCATACCATGCTCTTGCATCACCCAGCTCACACCCTATTGTAAGGGCATTGCCATTGTC
AACAGAGAGTTCAAAGACCTAAGCCTTGATGATTTTAAAATCACCAAATATTTGGTGCTTTTCTTCTGTCATTTGGACTT
CATCTTTGTGTGTCCTAACAAAAAATTGTTGTTTTACTGACAAAGCCCAATGAATTTCATGACATGAACTGTGAAGTTGT
TGCAATTTCAGTGCATCCCCTCTCCATCCATCTTGCCTAGATCAACACACCAAGGAAGAATGGTGGTTTGGGCCGCATGA
ACATTGTATTCTTGTCAGATTTGACTAAACAGATTTCCTGAGACTACAGTGGGCTGTTAGAAGGCCCAGGTAGTTGCTCT
CAGAGGACTTTTCATCATTGACCCCAGTGGAGGCATCAAGCACTTGAGTGTCAATGATCTCTCTCTCCTGGGCCACGGTG
TGGAAGAAACCCTCTGCTTGGTGAAGGTGTTCCAGTTTGTGGAAATCCACGGAGAAGTCTGCCCAGCAACCTGGATTCTC
CTACAATCATGCCACATCCAACTGCTTCCACAGAATACTTTGAGGCGGTTAATCAG

Alignment

ORF - retro_cfam_1322 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.25 %
• Parental protein coverage: 90.27 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 6

Retrocopy - Parental Gene Alignment:

Parental  ASAALR-PAASRRTCLTNVLWSGSGQAKFAFSTSSSYHAPA-VTQHAPYFKGTAVVNGEFKDLTLDDFK-
          ASAAL..PAA..RT.LTNVLWSGSGQ.KF.F.T..SYHA.A..TQ..PY.KG.A.VN.EFKDL.LDDFK.
Retrocopy ASAALA<PAAFQRTWLTNVLWSGSGQTKFTFRTNCSYHALA<ITQLTPYCKGIAIVNREFKDLSLDDFKI

Parental  GRYLVLFFYPLDFTFVCP-TEIVAFSDKAK-EFHDVNCDVVAVSVDSHFTHLAWINTPRKNGGLGHMNIA
          ..YLVLFF..LDF.FVCP.T....F.DKA..EFHD.NC.VVA.SV.....HLA.INTPRKNGGLG.MNI.
Retrocopy TKYLVLFFCHLDFIFVCP>TKNCCFTDKAQ>EFHDMNCEVVAISVHPLSIHLA*INTPRKNGGLGRMNIV

Parental  LLSDLTKQISRDYGVLLEGPG-IALRGLFIIDPNGVIKHLSVNDLPV-GRSVEETLRLVKAFQFVETHGE
          .LSDLTKQIS.DY..LLEGPG..ALRGLFIIDP.G.IKHLSVNDL...G..VEETL.LVK.FQFVE.HGE
Retrocopy FLSDLTKQIS*DYSGLLEGPG>VALRGLFIIDPSGGIKHLSVNDLSLLGHGVEETLCLVKVFQFVEIHGE

Parental  VC-PANWTPDSPTIKPHPTASKEYFEKVNQ
          VC.P.N...DSPTI.PHPTAS.EYFE.VNQ
Retrocopy VC<PSNL--DSPTIMPHPTASTEYFEAVNQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.21 RPM	24.70 RPM
SRP017611_brain	0.00 RPM	29.93 RPM
SRP017611_kidney	0.00 RPM	320.41 RPM
SRP017611_liver	0.00 RPM	80.34 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1322 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1322 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1322 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 25 parental genes, and 53 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000008731	1 retrocopy	retro_btau_562,
Canis familiaris	ENSCAFG00000004567	5 retrocopies	retro_cfam_1313, retro_cfam_270, retro_cfam_577, retro_cfam_834, retro_cfam_988,
Canis familiaris	ENSCAFG00000012109	3 retrocopies	retro_cfam_1322 , retro_cfam_219, retro_cfam_9,
Canis familiaris	ENSCAFG00000017163	3 retrocopies	retro_cfam_1603, retro_cfam_1624, retro_cfam_1739,
Callithrix jacchus	ENSCJAG00000019636	3 retrocopies	retro_cjac_1333, retro_cjac_3082, retro_cjac_653,
Ciona savignyi	ENSCSAVG00000001209	1 retrocopy	retro_csav_6,
Dasypus novemcinctus	ENSDNOG00000001359	3 retrocopies	retro_dnov_1052, retro_dnov_2373, retro_dnov_745,
Equus caballus	ENSECAG00000017026	1 retrocopy	retro_ecab_408,
Erinaceus europaeus	ENSEEUG00000009299	1 retrocopy	retro_eeur_238,
Homo sapiens	ENSG00000165672	3 retrocopies	retro_hsap_1253, retro_hsap_2587, retro_hsap_2653,
Gorilla gorilla	ENSGGOG00000026364	1 retrocopy	retro_ggor_986,
Macropus eugenii	ENSMEUG00000007732	3 retrocopies	retro_meug_1219, retro_meug_1735, retro_meug_62,
Microcebus murinus	ENSMICG00000007627	1 retrocopy	retro_mmur_475,
Myotis lucifugus	ENSMLUG00000012871	3 retrocopies	retro_mluc_1203, retro_mluc_1522, retro_mluc_2069,
Macaca mulatta	ENSMMUG00000008294	2 retrocopies	retro_mmul_1307, retro_mmul_1517,
Monodelphis domestica	ENSMODG00000009286	1 retrocopy	retro_mdom_1062,
Mustela putorius furo	ENSMPUG00000003074	1 retrocopy	retro_mputfur_1032,
Mus musculus	ENSMUSG00000024997	1 retrocopy	retro_mmus_2443,
Nomascus leucogenys	ENSNLEG00000016698	3 retrocopies	retro_nleu_1521, retro_nleu_2118, retro_nleu_2453,
Oryctolagus cuniculus	ENSOCUG00000017334	2 retrocopies	retro_ocun_135, retro_ocun_1434,
Pongo abelii	ENSPPYG00000002700	1 retrocopy	retro_pabe_1906,
Pan troglodytes	ENSPTRG00000002992	1 retrocopy	retro_ptro_29,
Ictidomys tridecemlineatus	ENSSTOG00000002537	2 retrocopies	retro_itri_1098, retro_itri_1753,
Tupaia belangeri	ENSTBEG00000011064	5 retrocopies	retro_tbel_3138, retro_tbel_3994, retro_tbel_710, retro_tbel_770, retro_tbel_811,
Tursiops truncatus	ENSTTRG00000010878	2 retrocopies	retro_ttru_1703, retro_ttru_881,