RetrogeneDB ID: retro_cjac_1491

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 16:96620724..96621623(+)
• Located in intron of: ENSCJAG00000015501

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCJAG00000020171
• Aliases: None
• Description: None

Sequence

>retro_cjac_1491
ATCTGGCCAAGCTCCGCCTCCTATGTGAATATGGAGAAGGAAAAGGCAAGGAGTGGACTTCCACAGAGAAGGCGAGGGAA
GAAGATCAGCGGGCTTCTAATCAACCAAACACAATTGCTTTGCCCGGAACATCAGCGAAGGGTGAAACCAAAGGAGAAAT
ATCTGTTAAAGGTGACAGAGTGCTCTGCCCTAAGAGGCAGGCAGAGTATGACAGCCCCAGACCTCAGAAGACACCAATCC
CTCCATTACCCTCTAAACTGCCACCTGTTAATCTGATCCACCAGGACATCGTGTGGGCCTGGTATCAACAATTAAAGCTT
AGCACCAGAGGCCAGAAACTGGACGCATTTAAGTGCCTGTGTGCCTTTGCTTACCCAAACCAAAAGGATTTTCCTAGCAC
AGCAAAAGAGGCCCACTCCAGAAATCATTGCAAAATAAATTAAAGGTGGAGAAAGGGAAAATGTGCTTGCAAAGTTCTGG
GACACAGCCTCCTCAAGTGGCTCTTCCCCTGCAGAAGGGCTGCCTGCTCTGAAAGAGCCTACTGCTCTCCTTGAGGGAGT
TAATACAGTTGTGGTGACAATTTCTGCCCCAGAGGCTGTGCTGGCCTCCTGGGTGAGAATATCAGCCAGGGCGAGGATGC
CAGAGGCAGTGGAATCTCCACAAGAAGCCAGCGGTGTCAGGTGGTATGTGGTCCATGGGAAAATCTCCCCGCAGACACCG
ATGGCTGGGTTCACCTGCAGTTTCATGCTGGTCAAGCCTGGGTTCCAGAAGAGCAAGAATGGAGTGAGTGCACTGTTCGT
CCTGCTTCCAGTTTTCCAGCCCCGCTCCTTGAAGATAATATGTTGTGCCCCAGATGTGTTCACAGGAACAAGCTCTTAAT
CAAAAGCCTCCAGTGGGAA

Alignment

ORF - retro_cjac_1491 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.82 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  IWPSFASCPNMEKVK-GKEWTSTEKAREEDQQASNPPNTSALPGTPAKGGTKGKVPVRGDKVLCPKKKA-
          IWPS.AS..NMEK.K.GKEWTSTEKAREEDQ.ASN.PNT.ALPGT.AKG.TKG...V.GD.VLCPK..A.
Retrocopy IWPSSASYVNMEKEK<GKEWTSTEKAREEDQRASNQPNTIALPGTSAKGETKGEISVKGDRVLCPKRQAE

Parental  -DNPRPQKKIPIPPLPSKLPPVNLIHRDIVRAWCQQLKLSTRGQKLDAYKRLCAFAYPNQKDFPSTAKEA
          .D.PRPQK..PIPPLPSKLPPVNLIH.DIV.AW.QQLKLSTRGQKLDA.K.LCAFAYPNQKDFPSTAKEA
Retrocopy YDSPRPQKT-PIPPLPSKLPPVNLIHQDIVWAWYQQLKLSTRGQKLDAFKCLCAFAYPNQKDFPSTAKEA

Parental  -KIRKSLQNKLKVEKGKACLQSSGTQPPQVALP-PAEGLPALEGPPSLLEGVNTVVVTTSAPEAVLASWA
          ....KSLQNKLKVEKGK.CLQSSGTQPPQVALP.PAEGLPAL..P..LLEGVNTVVVT.SAPEAVLASW.
Retrocopy <PLQKSLQNKLKVEKGKMCLQSSGTQPPQVALP<PAEGLPALKEPTALLEGVNTVVVTISAPEAVLASWV

Parental  RISARARTPEAVESPQEASGVRWCVVHGK-SLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFLLPASSF
          RISARAR.PEAVESPQEASGVRW.VVHGK..LPADTDGWVHLQFHAGQAWVPE.QE...S.....PASSF
Retrocopy RISARARMPEAVESPQEASGVRWYVVHGK<NLPADTDGWVHLQFHAGQAWVPEEQEW--SECTVRPASSF

Parental  PPPHLEDNMLCPKCVHRNKVLIKSLQWE
          P.P.LEDNMLCP.CVHRNK.LIKSLQWE
Retrocopy PAPLLEDNMLCPRCVHRNKLLIKSLQWE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.18 RPM	0.00 RPM
SRP051959_heart	0.14 RPM	0.00 RPM
SRP051959_kidney	0.00 RPM	0.00 RPM
SRP051959_liver	0.02 RPM	0.04 RPM
SRP051959_lung	0.03 RPM	0.00 RPM
SRP051959_lymph_node	0.00 RPM	0.00 RPM
SRP051959_skeletal_muscle	0.02 RPM	0.02 RPM
SRP051959_spleen	0.00 RPM	0.00 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_1491 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_1491 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_1491 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 20 parental genes, and 41 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000010335	5 retrocopies	retro_cfam_1332, retro_cfam_1540, retro_cfam_1905, retro_cfam_1934, retro_cfam_996,
Callithrix jacchus	ENSCJAG00000020168	4 retrocopies	retro_cjac_1378, retro_cjac_1991, retro_cjac_3832, retro_cjac_944,
Callithrix jacchus	ENSCJAG00000020171	2 retrocopies	retro_cjac_1334, retro_cjac_1491 ,
Echinops telfairi	ENSETEG00000002722	1 retrocopy	retro_etel_312,
Homo sapiens	ENSG00000121570	1 retrocopy	retro_hsap_893,
Gorilla gorilla	ENSGGOG00000015121	2 retrocopies	retro_ggor_1970, retro_ggor_723,
Loxodonta africana	ENSLAFG00000016804	1 retrocopy	retro_lafr_456,
Myotis lucifugus	ENSMLUG00000016423	1 retrocopy	retro_mluc_973,
Macaca mulatta	ENSMMUG00000016901	1 retrocopy	retro_mmul_1515,
Monodelphis domestica	ENSMODG00000018083	3 retrocopies	retro_mdom_1057, retro_mdom_1478, retro_mdom_999,
Mustela putorius furo	ENSMPUG00000010206	1 retrocopy	retro_mputfur_800,
Mus musculus	ENSMUSG00000058550	3 retrocopies	retro_mmus_1907, retro_mmus_2085, retro_mmus_3656,
Nomascus leucogenys	ENSNLEG00000004030	3 retrocopies	retro_nleu_2888, retro_nleu_3018, retro_nleu_388,
Oryctolagus cuniculus	ENSOCUG00000016435	1 retrocopy	retro_ocun_114,
Pongo abelii	ENSPPYG00000013565	3 retrocopies	retro_pabe_2316, retro_pabe_2349, retro_pabe_770,
Pan troglodytes	ENSPTRG00000015200	2 retrocopies	retro_ptro_1923, retro_ptro_616,
Pteropus vampyrus	ENSPVAG00000010677	1 retrocopy	retro_pvam_1237,
Rattus norvegicus	ENSRNOG00000025404	4 retrocopies	retro_rnor_2750, retro_rnor_2996, retro_rnor_861, retro_rnor_862,
Sarcophilus harrisii	ENSSHAG00000017398	1 retrocopy	retro_shar_542,
Tursiops truncatus	ENSTTRG00000009508	1 retrocopy	retro_ttru_1772,