RetrogeneDB ID: retro_ggor_723

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:70949276..70949832(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DPPA4
• Ensembl ID: ENSGGOG00000015121
• Aliases: None
• Description: None

Sequence

>retro_ggor_723
AAGCTCCTGTGTGCCTTTGCCTATCCAAATCAAAAGGATTTTCCTAGCACAGCAAAAGAGGCCAGAATCTGGAAATCATT
ACCAAAACAAAGGTGGACAAAGGGGAAATAACCCCGCAAAGCCCTGAGGAGACACATCCTCCTAAAGTAGCTCTTCCCCC
TGGGGAGGGGTTGCCTGACCTAGAAGAGTCTGCTGCTCTCCTTGAGGGAGTTAATACAGTTGTGGTGACAACTTCTGCCC
CAGAAGCTTCGCTGGCCTCCTGGGCCAGAAATGCAGCCAGGGAGACGGCACCAGAAGCAGTGGGATCTCCACATGAGGCC
CATGGTGTCAGGTGGCTAGTGTCCATGGGAGAAGACTCCCTGCAGACACAGATGGTTGGGTTCACCTCCAGTTTCATGCT
GGACAAGGCTGGGTTCCAGAAAAGCAAGAAGGGAGAGTGAGTGCACTCTTTTTGCTTCCTGCCTCCAATTTTCCACCCCC
ATACCTTGAAGACAATATGTTGTGCCCCAAATGCGTTCACAGGTACAAGGTCTTAATAAAAAGCCTCCGGTGGGAA

Alignment

ORF - retro_ggor_723 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.37 %
• Parental protein coverage: 61.18 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  KRLCAFAYPNQKDFPSTAKEAKIRKSLQKKLKVEKG-ETSLQSSE-THPPEVALPPAGGPPALENSTALL
          K.LCAFAYPNQKDFPSTAKEA.I.KSL.K.....KG.E...QS.E.THPP.VALPP..G.P.LE.S.ALL
Retrocopy KLLCAFAYPNQKDFPSTAKEARIWKSLPKQ-RWTKG<EITPQSPEETHPPKVALPPGEGLPDLEESAALL

Parental  EGVNTVVVTTSAPEALLASWARISARARTPEAVESPQEASGVRWCV-VHGKSLPADTDGWVHLQFHAGQA
          EGVNTVVVTTSAPEA.LASWAR..AR...PEAV.SP.EA.GVRW.V.VHG..LPADTDGWVHLQFHAGQ.
Retrocopy EGVNTVVVTTSAPEASLASWARNAARETAPEAVGSPHEAHGVRWLV<VHGRRLPADTDGWVHLQFHAGQG

Parental  WVPEKQEGRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
          WVPEKQEGRVSALFLLPASNFPPP.LEDNMLCPKCVHR.KVLIKSL.WE
Retrocopy WVPEKQEGRVSALFLLPASNFPPPYLEDNMLCPKCVHRYKVLIKSLRWE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	0.00 RPM
SRP007412_cerebellum	0.12 RPM	0.04 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.04 RPM
SRP007412_liver	0.00 RPM	0.13 RPM
SRP007412_testis	0.10 RPM	3.00 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_723 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_723 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_893
Pan troglodytes	retro_ptro_616
Pongo abelii	retro_pabe_770

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000010335	5 retrocopies	retro_cfam_1332, retro_cfam_1540, retro_cfam_1905, retro_cfam_1934, retro_cfam_996,
Callithrix jacchus	ENSCJAG00000020171	2 retrocopies	retro_cjac_1334, retro_cjac_1491,
Echinops telfairi	ENSETEG00000002722	1 retrocopy	retro_etel_312,
Homo sapiens	ENSG00000121570	1 retrocopy	retro_hsap_893,
Gorilla gorilla	ENSGGOG00000015121	2 retrocopies	retro_ggor_1970, retro_ggor_723 ,
Loxodonta africana	ENSLAFG00000016804	1 retrocopy	retro_lafr_456,
Myotis lucifugus	ENSMLUG00000016423	1 retrocopy	retro_mluc_973,
Macaca mulatta	ENSMMUG00000016901	1 retrocopy	retro_mmul_1515,
Monodelphis domestica	ENSMODG00000018083	3 retrocopies	retro_mdom_1057, retro_mdom_1478, retro_mdom_999,
Mustela putorius furo	ENSMPUG00000010206	1 retrocopy	retro_mputfur_800,
Mus musculus	ENSMUSG00000058550	3 retrocopies	retro_mmus_1907, retro_mmus_2085, retro_mmus_3656,
Nomascus leucogenys	ENSNLEG00000004030	3 retrocopies	retro_nleu_2888, retro_nleu_3018, retro_nleu_388,
Oryctolagus cuniculus	ENSOCUG00000016435	1 retrocopy	retro_ocun_114,
Pongo abelii	ENSPPYG00000013565	3 retrocopies	retro_pabe_2316, retro_pabe_2349, retro_pabe_770,
Pan troglodytes	ENSPTRG00000015200	2 retrocopies	retro_ptro_1923, retro_ptro_616,
Pteropus vampyrus	ENSPVAG00000010677	1 retrocopy	retro_pvam_1237,
Rattus norvegicus	ENSRNOG00000025404	4 retrocopies	retro_rnor_2750, retro_rnor_2996, retro_rnor_861, retro_rnor_862,
Sarcophilus harrisii	ENSSHAG00000017398	1 retrocopy	retro_shar_542,
Tursiops truncatus	ENSTTRG00000009508	1 retrocopy	retro_ttru_1772,