RetrogeneDB ID: retro_cjac_1511

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 16:38555549..38556416(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCJAG00000023197
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: PNP
• Ensembl ID: ENSCJAG00000009676
• Aliases: None
• Description: purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:7892]

Sequence

>retro_cjac_1511
ATGGAGAACGGATACACATATGAAGACTACAAAAACACTGCAGAATGGCTTCTGTCTCACACTAAACACCGACCTCAAGT
GGCAATAATCTGCGGTTCTGGATTAGGAGGTCTGACTGATAAATTAACTCAGGCCCAGGCCTTTGACTACAGTGAAATCC
CCAACTTTCCTCGAAGTACAGTGCCAGGTCATGCTGGCCGACTGGTGTTTGGGTTCCTGAACGGCAGAGCCTGTGTGATG
ATGCAGGGCAGGTTCCACATGTATGAAGGGTACTCACTCTGGAAGGTGACATTCCCAGTGAGGGTTTTCCACCTTCTGGG
TGTAGACACCCTGGTGGTCACCAATGCAGCTGGAGGGCTGAACCCCAAGTTTGAGGTTGGAGATATCATGCTGATCTGTG
ACCATATCAACCTACCTGGTTTCTCTGGTCAGAACCCTCTCAGAGGGCCCAATGATGAAAGGTTTGGAGTTCGTTTCCCT
GCCATGTCTGATGCCTACGACCGGACTATGAGGCAGAGGGCTCTCAGTGCCTGGAAACAAATGGGGGAGAAACGTGAGCT
ACAGGAAGGCACCTATGTGATGCTGGCAGGCCCCAGCTTTGAGACTGTGGCAGAATGTCTTCTGCTGCAGAAGCTGGGAG
CAGACGCTGTTGGCATGAGTACGGTGCCAGAAGTCATCGTTGCACGGCACTGTGGGCTTCGAGTCTTTGGCTTCTCACTC
ATTACTAACAAGGTCATCTTGGATTATGAAAGCCTGGAGAAGGCCAACCACGAAGAAGTATTAGAGGTTAGCAAACAAGC
TGCACAGAAGTTGGAAAGATTTGTCTCCATTCTTATGTCCAGCATTCCACTCCCTGACAAAGCCAGT

Alignment

ORF - retro_cjac_1511 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.96 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MENGYTYEDYKNTAEWLLSHTKHRPQVAVICGSGLGGLTDKLTQAQAFDYSEIPNFPRSTVPGHAGRLVF
          MENGYTYEDYKNTAEWLLSHTKHRPQVA.ICGSGLGGLTDKLTQAQAFDYSEIPNFPRSTVPGHAGRLVF
Retrocopy MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQAFDYSEIPNFPRSTVPGHAGRLVF

Parental  GFLNGRACVMMQGRFHMYEGYSLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLICDHINLPG
          GFLNGRACVMMQGRFHMYEGYSLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLICDHINLPG
Retrocopy GFLNGRACVMMQGRFHMYEGYSLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLICDHINLPG

Parental  FSGQNPLRGPNDERFGVRFPAMSDAYDRTMRQRALSAWKQMGEKRELQEGTYVMLAGPSFETVAECRLLQ
          FSGQNPLRGPNDERFGVRFPAMSDAYDRTMRQRALSAWKQMGEKRELQEGTYVMLAGPSFETVAEC.LLQ
Retrocopy FSGQNPLRGPNDERFGVRFPAMSDAYDRTMRQRALSAWKQMGEKRELQEGTYVMLAGPSFETVAECLLLQ

Parental  KLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVILDYESLEKANHEEVLEASKQAAQKLERFVSILMS
          KLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVILDYESLEKANHEEVLE.SKQAAQKLERFVSILMS
Retrocopy KLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVILDYESLEKANHEEVLEVSKQAAQKLERFVSILMS

Parental  SIPLPDKAS
          SIPLPDKAS
Retrocopy SIPLPDKAS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.00 RPM	7.39 RPM
SRP051959_heart	0.00 RPM	3.07 RPM
SRP051959_kidney	0.84 RPM	294.52 RPM
SRP051959_liver	0.00 RPM	1.58 RPM
SRP051959_lung	0.02 RPM	8.65 RPM
SRP051959_lymph_node	0.02 RPM	11.37 RPM
SRP051959_skeletal_muscle	0.02 RPM	2.05 RPM
SRP051959_spleen	0.02 RPM	7.75 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_1511 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_1511 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_1511 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 33 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005373	1 retrocopy	retro_amel_1666,
Bos taurus	ENSBTAG00000012317	1 retrocopy	retro_btau_1463,
Choloepus hoffmanni	ENSCHOG00000009274	5 retrocopies	retro_chof_1328, retro_chof_1595, retro_chof_1827, retro_chof_1933, retro_chof_348,
Callithrix jacchus	ENSCJAG00000009676	2 retrocopies	retro_cjac_1195, retro_cjac_1511 ,
Dasypus novemcinctus	ENSDNOG00000011630	1 retrocopy	retro_dnov_322,
Erinaceus europaeus	ENSEEUG00000002411	1 retrocopy	retro_eeur_541,
Felis catus	ENSFCAG00000006934	1 retrocopy	retro_fcat_1368,
Homo sapiens	ENSG00000198805	1 retrocopy	retro_hsap_2282,
Gorilla gorilla	ENSGGOG00000002126	1 retrocopy	retro_ggor_1695,
Macropus eugenii	ENSMEUG00000014512	3 retrocopies	retro_meug_1282, retro_meug_1560, retro_meug_211,
Macaca mulatta	ENSMMUG00000019126	1 retrocopy	retro_mmul_287,
Mustela putorius furo	ENSMPUG00000018119	2 retrocopies	retro_mputfur_420, retro_mputfur_822,
Nomascus leucogenys	ENSNLEG00000010969	1 retrocopy	retro_nleu_1964,
Otolemur garnettii	ENSOGAG00000013344	4 retrocopies	retro_ogar_1631, retro_ogar_2141, retro_ogar_3083, retro_ogar_594,
Pongo abelii	ENSPPYG00000005567	1 retrocopy	retro_pabe_1938,
Pan troglodytes	ENSPTRG00000006095	1 retrocopy	retro_ptro_1616,
Pteropus vampyrus	ENSPVAG00000010734	1 retrocopy	retro_pvam_1302,
Rattus norvegicus	ENSRNOG00000009982	1 retrocopy	retro_rnor_891,
Tupaia belangeri	ENSTBEG00000016378	1 retrocopy	retro_tbel_4632,
Tarsius syrichta	ENSTSYG00000000748	3 retrocopies	retro_tsyr_2057, retro_tsyr_2127, retro_tsyr_235,