RetrogeneDB ID: retro_dmel_82

Retrocopy location

• Organism: Fruit fly (Drosophila melanogaster)
• Coordinates: 2L:12453672..12454783(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: FBgn0032437
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ade5
• Ensembl ID: FBgn0020513
• Aliases: None
• Description: ade5 [Source:FlyBase gene name;Acc:FBgn0020513]

Sequence

>retro_dmel_82
TTGCCAACCATGTCAATCACAACCATTGGAGGCTACCAATTGGGCAAGATCCTGATCGAAGGCAAGACCAAGAAGGTGTA
CGACCTACCGGATCATCCAGGATTATGTCTGCTGTTGAGCAAGGATCGCATTACAGCTTTTGATGGACTCATGGCCCATG
AGCTTCAAGGCAAGGCGGCTATCTCAAATACCACAAATGGACTGGTTTTTAGGCTACTCAATGAGGCGGGAATCCGAACC
GCTTACGTGGATCAGTGTGGCGATAACGCTTTTATAGCACGAAAATGCCAGATGGTGCACATAGAGTGGGTGACGCGTCG
TTTGGCCACCGGATCTTTTATCAAATTAAATCCGGAAGTGCCCGAAGGATATCGATTTGCACCACCAAAGCAAGAGACTT
GCTTCAAGGACGATTCTAGTCACGATCCCCTGTGGTGCGATGAGCAAATTCTCTCCTCGAATTTTGAGTGCAATGGCCTA
ATAATTGGCGCAGACGAAGTTCAAATAATGCGACGCACTTCACTAGTGGTATTCGAAGTTCTCGAAAGAGCATGGAAAAC
AAAGAACTGTGCCTTGGTGGACATGAAGGTTGAATTCGGTGTGGACGAAGATGGCAACATATTGCTGGCGGACATAATTG
ACTCGGATACGTGGCGCATTTGGCCGGCGGGCGACAAACGGCTAATGGTGGACAAAACCGTGTATATAAATTTGGATACA
GTAACCGATAGCGATTTGAATACAGTCAAGCGCAATTATTCTTGGGTAATAGAGCAGCTATCGAGCATTGCGCCGCCCCA
GGACCATCTGGTGGTAATCCTAGTGAGTAGTGAAATGGATGTGGAACATGGCGAACAGATCGCCACCTGCATTGGATCAC
TAGGCATGAAAGTGGTGCTCCGAGTGTGTTCTGTTTAGCGAAAATCCCGAAGAAGCGCTCCAAATTCTCCGGACATTCGA
GGCGGTGATTAATAATCTGGTATTCGTGACCGTCGACGAGCGATTAAATAGTTTGGCCAACGTGATTTCGGCCAACACCA
GTTTTCCGGTGATCAATTGTACGCCCATTCAATCCGACACCATGTTTATGAATATGTGGTCCAACTCGAAT

Alignment

ORF - retro_dmel_82 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.65 %
• Parental protein coverage: 86.25 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MSTTTTASIEGYKLGKVIIEGKTKQVYDLPEQPGLCLLLSKDRITAGDGVKAHDLAGKAEISNTTNGQVF
          ..T.....I.GY.LGK..IEGKTK.VYDLP..PGLCLLLSKDRITA.DG..AH.L.GKA.ISNTTNG.VF
Retrocopy LPTMSITTIGGYQLGKILIEGKTKKVYDLPDHPGLCLLLSKDRITAFDGLMAHELQGKAAISNTTNGLVF

Parental  RLLNEAGIRTAYVKQCGAKAFIARKCQMIPIEWVTRRLATGSFLKRNVGVPEGYRFSPPKQETFFKDDAN
          RLLNEAGIRTAYV.QCG..AFIARKCQM..IEWVTRRLATGSF.K.N..VPEGYRF.PPKQET.FKDD..
Retrocopy RLLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRRLATGSFIKLNPEVPEGYRFAPPKQETCFKDDSS

Parental  HDPQWSEEQIVSAKFELNGLVIGQDEVDIMRRTTLLVFEILERAWQTKNCALIDMKVEFGICDDGNIVLA
          HDP.W..EQI.S..FE.NGL.IG.DEV.IMRRT.L.VFE.LERAW.TKNCAL.DMKVEFG...DGNI.LA
Retrocopy HDPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVLERAWKTKNCALVDMKVEFGVDEDGNILLA

Parental  DIIDSDSWRLWPAGDKRLMVDKQVYRNLASVTASDLDTVKRNFIWVAEQLADIVPKKDHLVVILMGSASD
          DIIDSD.WR.WPAGDKRLMVDK.VY.NL..VT.SDL.TVKRN..WV.EQL..I.P..DHLVVIL..S..D
Retrocopy DIIDSDTWRIWPAGDKRLMVDKTVYINLDTVTDSDLNTVKRNYSWVIEQLSSIAPPQDHLVVILVSSEMD

Parental  ISHSEKIATSCRSLGLNVELRVSSA-HKGPEETLRIVREYESVMSNLIFVAVAGRSNGLGPVVSGSTNYP
          ..H.E.IAT...SLG..V.LRV.S.....PEE.L.I.R..E.V..NL.FV.V..R.N.L..V.S..T..P
Retrocopy VEHGEQIATCIGSLGMKVVLRVCSV>SENPEEALQILRTFEAVINNLVFVTVDERLNSLANVISANTSFP

Parental  VINCPPVKSDNMQVDVWSSLN
          VINC.P..SD.M....WS..N
Retrocopy VINCTPIQSDTMFMNMWSNSN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Drosophila melanogaster was not studied using RNA-Seq expression data.

ChIP-Seq

Drosophila melanogaster was not studied using ChIP-Seq data.

EST

2 EST(s) were mapped to retro_dmel_82 retrocopy

EST ID	Start	End	Identity	Match	Mis-match	Score
CO323696	12453663	12454103	99.6	438	2	436
EC200398	12453663	12454140	99.6	475	2	473

TSS

Drosophila melanogaster was not studied using FANTOM5 data.

Lab

retro_dmel_82 was not experimentally validated.

Homology

Retrocopy orthology:

Drosophila melanogaster does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 29 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000010577	1 retrocopy	retro_btau_508,
Cavia porcellus	ENSCPOG00000010749	1 retrocopy	retro_cpor_969,
Dasypus novemcinctus	ENSDNOG00000013413	1 retrocopy	retro_dnov_284,
Echinops telfairi	ENSETEG00000015242	2 retrocopies	retro_etel_1918, retro_etel_341,
Homo sapiens	ENSG00000128050	3 retrocopies	retro_hsap_3802, retro_hsap_3915, retro_hsap_3927,
Gorilla gorilla	ENSGGOG00000024392	1 retrocopy	retro_ggor_2643,
Mus musculus	ENSMUSG00000029247	6 retrocopies	retro_mmus_1748, retro_mmus_2750, retro_mmus_2858, retro_mmus_3126, retro_mmus_653, retro_mmus_971,
Nomascus leucogenys	ENSNLEG00000008786	2 retrocopies	retro_nleu_1274, retro_nleu_2156,
Otolemur garnettii	ENSOGAG00000003575	2 retrocopies	retro_ogar_2138, retro_ogar_865,
Procavia capensis	ENSPCAG00000008531	1 retrocopy	retro_pcap_172,
Pan troglodytes	ENSPTRG00000016081	2 retrocopies	retro_ptro_2662, retro_ptro_2670,
Rattus norvegicus	ENSRNOG00000002101	3 retrocopies	retro_rnor_1891, retro_rnor_2768, retro_rnor_804,
Tupaia belangeri	ENSTBEG00000006751	1 retrocopy	retro_tbel_3697,
Tarsius syrichta	ENSTSYG00000010497	2 retrocopies	retro_tsyr_2170, retro_tsyr_329,
Drosophila melanogaster	FBgn0020513	1 retrocopy	retro_dmel_82 ,