RetrogeneDB ID: retro_eeur_401

Retrocopy location

• Organism: Hedgehog (Erinaceus europaeus)
• Coordinates: scaffold_285280:5652..6045(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: COQ10B
• Ensembl ID: ENSEEUG00000001626
• Aliases: None
• Description: coenzyme Q10 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25819]

Sequence

>retro_eeur_401
CATTTTGTCCCTTGGTGTAAAAAATCTGATATAATATCAAGGAGATCCGGATACTGTAAAACACGATTAGAAATTGGGTT
CCCACCTGTACTGGAGCACTATACATTAGTGAAACCACATTTGGTAAAGGCATCCTGTACTGATGGGAAGCTTTTCAACC
ACTTAAGAGACTGGTGTTTTAGCCCAGGTCTTCCTGGTTACCCAAGAACCTGCACATTGGACTTTTCAATTTCTTTTGAA
TTTCGCTCACTTCTACACTCTCAGCTTGCCACGATGTTTTTTGATGAAGTCATGAAGCAGATGGTAGCTGCCTTTGAAAG
AAGAGCATGTAAGCTGTATGGTCCAGAAACAAACATACCTAGGGAATTAATGTTTCATGAAGTTCATCACACA

Alignment

ORF - retro_eeur_401 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.38 %
• Parental protein coverage: 67. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  HFVPWCKKSDIISRRSGYCKTRLEIGFPPVLEHYTSVVTLVKPHLVKASCTDGKLFNHLETVWRFSPGLP
          HFVPWCKKSDIISRRSGYCKTRLEIGFPPVLEHY....TLVKPHLVKASCTDGKLFNHL...W.FSPGLP
Retrocopy HFVPWCKKSDIISRRSGYCKTRLEIGFPPVLEHY----TLVKPHLVKASCTDGKLFNHLRD-WCFSPGLP

Parental  GYPRTCTLDFSISFEFRSLLHSQLATMFFDEVVKQMVAAFERRACKLYGPETNIPRELMFHEVHHT
          GYPRTCTLDFSISFEFRSLLHSQLATMFFDEV.KQMVAAFERRACKLYGPETNIPRELMFHEVHHT
Retrocopy GYPRTCTLDFSISFEFRSLLHSQLATMFFDEVMKQMVAAFERRACKLYGPETNIPRELMFHEVHHT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.48 RPM	12.09 RPM
SRP017611_kidney	0.00 RPM	13.13 RPM
SRP017611_liver	0.16 RPM	8.52 RPM

ChIP-Seq

Erinaceus europaeus was not studied using ChIP-Seq data.

EST

Erinaceus europaeus was not studied using EST data.

TSS

Erinaceus europaeus was not studied using FANTOM5 data.

Lab

retro_eeur_401 was not experimentally validated.

Homology

Retrocopy orthology:

Erinaceus europaeus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 26 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000004659	2 retrocopies	retro_btau_1595, retro_btau_1832,
Choloepus hoffmanni	ENSCHOG00000005807	1 retrocopy	retro_chof_1504,
Callithrix jacchus	ENSCJAG00000003971	1 retrocopy	retro_cjac_1836,
Dasypus novemcinctus	ENSDNOG00000003229	2 retrocopies	retro_dnov_1571, retro_dnov_2203,
Dipodomys ordii	ENSDORG00000004090	1 retrocopy	retro_dord_508,
Erinaceus europaeus	ENSEEUG00000001626	1 retrocopy	retro_eeur_401 ,
Felis catus	ENSFCAG00000022385	1 retrocopy	retro_fcat_1487,
Homo sapiens	ENSG00000115520	1 retrocopy	retro_hsap_3349,
Gorilla gorilla	ENSGGOG00000023373	2 retrocopies	retro_ggor_2270, retro_ggor_569,
Myotis lucifugus	ENSMLUG00000000865	1 retrocopy	retro_mluc_1236,
Macaca mulatta	ENSMMUG00000010488	1 retrocopy	retro_mmul_2434,
Monodelphis domestica	ENSMODG00000012281	1 retrocopy	retro_mdom_600,
Mus musculus	ENSMUSG00000025981	1 retrocopy	retro_mmus_3224,
Nomascus leucogenys	ENSNLEG00000006871	1 retrocopy	retro_nleu_1172,
Ochotona princeps	ENSOPRG00000010091	3 retrocopies	retro_opri_1020, retro_opri_173, retro_opri_664,
Pongo abelii	ENSPPYG00000013045	2 retrocopies	retro_pabe_2758, retro_pabe_576,
Pan troglodytes	ENSPTRG00000012772	1 retrocopy	retro_ptro_2137,
Rattus norvegicus	ENSRNOG00000014456	1 retrocopy	retro_rnor_1620,
Tarsius syrichta	ENSTSYG00000012642	2 retrocopies	retro_tsyr_1213, retro_tsyr_1666,