RetrogeneDB ID: retro_ggor_2098

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 4:76674250..76674844(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: APOO
• Ensembl ID: ENSGGOG00000001200
• Aliases: None
• Description: None

Sequence

>retro_ggor_2098
ATGTTCAAGGTAATTCGGAGGTCCGTGAGGCCAACCAGCCTACGCTTGTTCACCTTCAAAGTCTATGCAGCACCAAAAAA
GGACTCACCTCCTCAAAATCCCATGAAGGTTGATGAGCTTTCACTGTACTCAGTTCCCGAGGGTCAATCGAAGTGTGTGG
AAGAGTCAAGGAGCCAGCTTGAAGTAGGCATCTCACAGTTCCGACGCTATTGTGAGCCACATAGAAATTTGTGTCAGGAA
ACGTACTCCCAAACTAAGCCTAAGATGCAAAGTTTGGTTCAGTGGGGATTAGACAGCTATGCGTATCTCTAAAATGCACC
TCCTGGATTTTTTCCAAGACTTGCTGTTATTGGTTTTGCTGGCCTTAATGGACTCTTTTTGGCTAGAGGTTCAAAAATAA
AGAAGCTAGTGTGTCCACCTGGTTTCATGGGATTAGCTGCCTCCACCTGTTATCCACAACAAGCCATCGTGTTTGCCAAG
TTCAGTGGGGAGAGATCATATGACTGGGGTTTACACGGATATATAGTAATAGAAGATTTGTGGAAGGAGAACTTTTAAAA
GCCAGGAAATGTGAAGAATTCACCTGGAACTAAG

Alignment

ORF - retro_ggor_2098 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.84 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MFKVIQRSVGPASLSLLTFKVYAAPKKDSPPKNSVKVDELSLYSVPEGQSKYVEEARSQLEESISQLRHY
          MFKVI.RSV.P.SL.L.TFKVYAAPKKDSPP.N..KVDELSLYSVPEGQSK.VEE.RSQLE..ISQ.R.Y
Retrocopy MFKVIRRSVRPTSLRLFTFKVYAAPKKDSPPQNPMKVDELSLYSVPEGQSKCVEESRSQLEVGISQFRRY

Parental  CEPYTTWCQETYSQTKPKMQSLVQWGLDSYDYLQNAPPGFFLRLGVIGFAGLIGLLLARGSKIKKLVYPP
          CEP....CQETYSQTKPKMQSLVQWGLDSY.YL.NAPPGFF.RL.VIGFAGL.GL.LARGSKIKKLV.PP
Retrocopy CEPHRNLCQETYSQTKPKMQSLVQWGLDSYAYL*NAPPGFFPRLAVIGFAGLNGLFLARGSKIKKLVCPP

Parental  GFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGNVKNSPGTK
          GFMGLAAS..YPQQAIVFA..SGER.YDWGL.GYIVIEDLWKENF.KPGNVKNSPGTK
Retrocopy GFMGLAASTCYPQQAIVFAKFSGERSYDWGLHGYIVIEDLWKENF*KPGNVKNSPGTK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	14.10 RPM
SRP007412_cerebellum	0.00 RPM	8.98 RPM
SRP007412_heart	0.00 RPM	6.41 RPM
SRP007412_kidney	0.00 RPM	14.60 RPM
SRP007412_liver	0.00 RPM	4.04 RPM
SRP007412_testis	0.10 RPM	4.97 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2098 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2098 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Macaca mulatta	retro_mmul_1886

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 61 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012749	1 retrocopy	retro_amel_1282,
Choloepus hoffmanni	ENSCHOG00000000226	2 retrocopies	retro_chof_2372, retro_chof_839,
Callithrix jacchus	ENSCJAG00000004909	8 retrocopies	retro_cjac_1360, retro_cjac_1417, retro_cjac_1448, retro_cjac_1767, retro_cjac_1792, retro_cjac_1896, retro_cjac_2038, retro_cjac_2063,
Dasypus novemcinctus	ENSDNOG00000006710	1 retrocopy	retro_dnov_2450,
Equus caballus	ENSECAG00000013441	1 retrocopy	retro_ecab_145,
Echinops telfairi	ENSETEG00000014150	3 retrocopies	retro_etel_1052, retro_etel_516, retro_etel_711,
Felis catus	ENSFCAG00000000029	3 retrocopies	retro_fcat_1203, retro_fcat_1657, retro_fcat_1798,
Homo sapiens	ENSG00000184831	5 retrocopies	retro_hsap_1018, retro_hsap_1693, retro_hsap_2670, retro_hsap_3047, retro_hsap_3259,
Gorilla gorilla	ENSGGOG00000001200	4 retrocopies	retro_ggor_1269, retro_ggor_1863, retro_ggor_2098 , retro_ggor_806,
Gorilla gorilla	ENSGGOG00000016329	1 retrocopy	retro_ggor_2213,
Loxodonta africana	ENSLAFG00000029070	1 retrocopy	retro_lafr_1114,
Macropus eugenii	ENSMEUG00000014222	1 retrocopy	retro_meug_700,
Macaca mulatta	ENSMMUG00000016361	4 retrocopies	retro_mmul_1584, retro_mmul_1886, retro_mmul_2051, retro_mmul_814,
Monodelphis domestica	ENSMODG00000025554	1 retrocopy	retro_mdom_1510,
Mustela putorius furo	ENSMPUG00000000109	1 retrocopy	retro_mputfur_109,
Mus musculus	ENSMUSG00000079508	1 retrocopy	retro_mmus_282,
Nomascus leucogenys	ENSNLEG00000010026	5 retrocopies	retro_nleu_1167, retro_nleu_1338, retro_nleu_1944, retro_nleu_456, retro_nleu_898,
Pongo abelii	ENSPPYG00000020191	7 retrocopies	retro_pabe_1394, retro_pabe_1417, retro_pabe_2215, retro_pabe_2417, retro_pabe_2434, retro_pabe_2702, retro_pabe_856,
Pan troglodytes	ENSPTRG00000021742	5 retrocopies	retro_ptro_1147, retro_ptro_1799, retro_ptro_1992, retro_ptro_2205, retro_ptro_746,
Pteropus vampyrus	ENSPVAG00000002530	2 retrocopies	retro_pvam_128, retro_pvam_594,
Sarcophilus harrisii	ENSSHAG00000008734	1 retrocopy	retro_shar_125,
Sus scrofa	ENSSSCG00000012174	1 retrocopy	retro_sscr_774,
Tarsius syrichta	ENSTSYG00000010239	2 retrocopies	retro_tsyr_1089, retro_tsyr_2155,