RetrogeneDB ID:

retro_hsap_1673

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:16:30832392..30832835(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000260082
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:C20orf27
Ensembl ID:ENSG00000101220
Aliases:None
Description:chromosome 20 open reading frame 27 [Source:HGNC Symbol;Acc:15873]


Retrocopy-Parental alignment summary:






>retro_hsap_1673
TCCCAGAGCCACGTCTGCTTTGATGAGAGGCTTCATGACTCGGTGGTCATGGCCACCCAGGACAGCGACAGCAGCTTTCT
GGTCAAGGTTGGCTTCCTGAAGATCCTGCGCAGGTATGAGATTACCTTCACTCTTCCCCCGCCCAGTGAGCAAGCACGTC
CGTGAGGCACCTGTTCCCAGCCTCTGCATGTCAAGCTCCTCAGCGTTGTTCCTGTCCCTGAAGGTTACAGTGTCAAGTGC
GAGTACTCAGCGCACAAAGAGGGTGTCCTCAAAGCCGCGATGCTGCCAGCCTGCGAAGGTGGCGCCGGCGCCTGTGTGAG
CGTGGCAGTGCAGGCTGGCGCCAGGGGCCGACACCACGGCATGCCCACCTGCTGGACGGTGTCAAGGGCTCGGGCGCCGC
GCTGGAATAAGACTCGCAGCACAGCCACTGGCACGGCTTTGAC

ORF - retro_hsap_1673 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 72. %
Parental protein coverage: 85.63 %
Number of stop codons detected: 2
Number of frameshifts detected 1


Retrocopy - Parental Gene Alignment:

ParentalSHSHVHFDEKLHDSVVMVTQESDSSFLVKVGFLKILHRYEITFTLPPVHRLSKDVREAPVPSLHLKLLSV
S.SHV.FDE.LHDSVVM.TQ.SDSSFLVKVGFLKIL.RYEITFTLPP.............P.LH.KLLSV
RetrocopySQSHVCFDERLHDSVVMATQDSDSSFLVKVGFLKILRRYEITFTLPPPSEQARP*GTCSQP-LHVKLLSV
ParentalVPVPEGYSVKCEYSAHKEGVLKEEILLACEGGTGTCVRVTVQARVMDRHHGTPM-LLDGVKCVGAELEYD
VPVPEGYSVKCEYSAHKEGVLK...L.ACEGG.G.CV.V.VQA....RHHG.P..LLDGVK..GA.LE.D
RetrocopyVPVPEGYSVKCEYSAHKEGVLKAAMLPACEGGAGACVSVAVQAGARGRHHGMPT<LLDGVKGSGAALE*D
ParentalSEHSDWHGFD
S.HS.WHGFD
RetrocopySQHSHWHGFD

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 0 .24 RPM 15 .45 RPM
bodymap2_adrenal 0 .02 RPM 19 .81 RPM
bodymap2_brain 0 .19 RPM 6 .66 RPM
bodymap2_breast 0 .02 RPM 18 .62 RPM
bodymap2_colon 0 .43 RPM 31 .42 RPM
bodymap2_heart 0 .04 RPM 3 .82 RPM
bodymap2_kidney 0 .04 RPM 5 .93 RPM
bodymap2_liver 0 .04 RPM 3 .61 RPM
bodymap2_lung 0 .33 RPM 4 .38 RPM
bodymap2_lymph_node 0 .00 RPM 10 .49 RPM
bodymap2_ovary 0 .93 RPM 28 .65 RPM
bodymap2_prostate 0 .28 RPM 43 .02 RPM
bodymap2_skeletal_muscle 0 .18 RPM 4 .11 RPM
bodymap2_testis 0 .68 RPM 11 .46 RPM
bodymap2_thyroid 0 .09 RPM 7 .46 RPM
bodymap2_white_blood_cells 0 .04 RPM 25 .40 RPM

ChIP-Seq - click to see more details

RNA Polymerase II actvity near the 5' end of retro_hsap_1673 was not detected

EST - click to see more details

No EST(s) were mapped for retro_hsap_1673 retrocopy.

TSS - click to see more details

No TSS is located nearby retro_hsap_1673 retrocopy 5' end.

Lab - click to see more details

retro_hsap_1673 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_1673 has 1 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Pan troglodytes retro_ptro_1136
Parental genes homology:
Parental genes homology involve 7 parental genes, and 9 retrocopies.

Species Parental gene accession Retrocopies number
Callithrix jacchus ENSCJAG000000211941 retrocopy
retro_cjac_3292,
Homo sapiens ENSG00000101220 2 retrocopies
retro_hsap_1114, retro_hsap_1673 ,
Gorilla gorilla ENSGGOG000000169871 retrocopy
retro_ggor_871,
Macaca mulatta ENSMMUG000000220791 retrocopy
retro_mmul_1578,
Nomascus leucogenys ENSNLEG000000076531 retrocopy
retro_nleu_194,
Pongo abelii ENSPPYG000000108131 retrocopy
retro_pabe_923,
Pan troglodytes ENSPTRG000000132042 retrocopies
retro_ptro_1136, retro_ptro_685,

Expression level across human populations :
image/svg+xml GBR_HG00142 GBR_HG00099 GBR_HG00114 GBR_HG00143 GBR_HG00131 GBR_HG00137 GBR_HG00133 GBR_HG00119 GBR_HG00111 GBR_HG00134 FIN_HG00378 FIN_HG00338 FIN_HG00349 FIN_HG00375 FIN_HG00315 FIN_HG00277 FIN_HG00328 FIN_HG00321 FIN_HG00377 FIN_HG00183 TSI_NA20756 TSI_NA20538 TSI_NA20798 TSI_NA20532 TSI_NA20765 TSI_NA20518 TSI_NA20513 TSI_NA20512 TSI_NA20771 TSI_NA20786 YRI_NA19114 YRI_NA19099 YRI_NA18870 YRI_NA18907 YRI_NA19223 YRI_NA19214 YRI_NA18916 YRI_NA19093 YRI_NA19118 YRI_NA19213 Toscaniin Italia: Finnish inFinland: British in England and Scotland: Utah Residents (CEPH) with Northernand Western European Ancestry: Yoruba in Ibadan, Nigeria: CEU_NA12760 CEU_NA12827 CEU_NA12872 CEU_NA12751 CEU_NA12873 CEU_NA12400 CEU_NA11930 CEU_NA12004 CEU_NA11831 CEU_NA11843 No expression ( = 0 RPM ) > 0 RPM = 0.19 RPM Legend:


Library Retrogene expression
CEU_NA11831 0 .11 RPM
CEU_NA11843 0 .06 RPM
CEU_NA11930 0 .00 RPM
CEU_NA12004 0 .00 RPM
CEU_NA12400 0 .11 RPM
CEU_NA12751 0 .00 RPM
CEU_NA12760 0 .09 RPM
CEU_NA12827 0 .05 RPM
CEU_NA12872 0 .03 RPM
CEU_NA12873 0 .06 RPM
FIN_HG00183 0 .08 RPM
FIN_HG00277 0 .04 RPM
FIN_HG00315 0 .00 RPM
FIN_HG00321 0 .00 RPM
FIN_HG00328 0 .07 RPM
FIN_HG00338 0 .00 RPM
FIN_HG00349 0 .00 RPM
FIN_HG00375 0 .07 RPM
FIN_HG00377 0 .03 RPM
FIN_HG00378 0 .04 RPM
GBR_HG00099 0 .06 RPM
GBR_HG00111 0 .02 RPM
GBR_HG00114 0 .05 RPM
GBR_HG00119 0 .00 RPM
GBR_HG00131 0 .06 RPM
GBR_HG00133 0 .05 RPM
GBR_HG00134 0 .02 RPM
GBR_HG00137 0 .14 RPM
GBR_HG00142 0 .19 RPM
GBR_HG00143 0 .00 RPM
TSI_NA20512 0 .00 RPM
TSI_NA20513 0 .00 RPM
TSI_NA20518 0 .06 RPM
TSI_NA20532 0 .10 RPM
TSI_NA20538 0 .00 RPM
TSI_NA20756 0 .06 RPM
TSI_NA20765 0 .06 RPM
TSI_NA20771 0 .03 RPM
TSI_NA20786 0 .03 RPM
TSI_NA20798 0 .03 RPM
YRI_NA18870 0 .03 RPM
YRI_NA18907 0 .00 RPM
YRI_NA18916 0 .00 RPM
YRI_NA19093 0 .00 RPM
YRI_NA19099 0 .00 RPM
YRI_NA19114 0 .03 RPM
YRI_NA19118 0 .00 RPM
YRI_NA19213 0 .05 RPM
YRI_NA19214 0 .12 RPM
YRI_NA19223 0 .06 RPM

Indel association:

No indels were associated with its genomic coordinates. Based on Kabza et al. 2015 (PubMed).



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