RetrogeneDB ID: retro_mmul_613

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 10:64759491..64760083(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000013177
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: TMED2
• Ensembl ID: ENSMMUG00000031491
• Aliases: None
• Description: None

Sequence

>retro_mmul_613
ATGGTGACCCTTGCTGACCTGCTGGTGCTCCTAGCCGCGCTCCTGGCCATGGTCTCAGGCTACTTTATTAGCATCAACCC
ACATGCCGAGGAGTGCTTCTTTGAGTGGGTCGCCTCGGGTACCAAGATGGGCCTCATCTCTGAGGTGGTGGAGGGCGGCT
TCCTGGACATTAATGTGGAGATAATAGGACCAGATAACAAAGGGATTTACAGAGGAGACGGAGAATCCAGTGGGAAATAC
ACATTTGCTGCTCACATGGATTCCGAAGTTTGTTTTAGTAACCGGATGTCTACCATGACTCCAAAAATAGTGATGTTCAC
CATTGATACTGGGGAGGCTCCAAAAGGACAAGACATGGAAAAAGCAGCTCACCAGAACAACTTAGAAGAAATGATCAGTG
AGCTAGCAGTGGCGATGACAGCTGGAAAGCACAAACAGGAATACATGGAAATCGGGAGAGGATACATGGAGCCATCAACA
ACAACACAAACAGCAGAGTGGTTCTTTGGTCCTTGAAGCTCTTGTTCTAGTTGCCATGACATTGGGACAGATCTACTACC
TGAAGAGCTTTTTTGAAGTCCAGAGGCTTATT

Alignment

ORF - retro_mmul_613 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.27 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIY
          MVTLA.LLVLLAALLA.VSGYF.SI..HAEECFFE.V.SGTKMGLI.EV.EGGFLDI.VEI.GPDNKGIY
Retrocopy MVTLADLLVLLAALLAMVSGYFISINPHAEECFFEWVASGTKMGLISEVVEGGFLDINVEIIGPDNKGIY

Parental  KGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVA
          .GD.ESSGKYTFAAHMD.....CFSNRMSTMTPKIVMFTID.GEAPKGQDME..AHQN.LEEMI.ELAVA
Retrocopy RGDGESSGKYTFAAHMDS--EVCFSNRMSTMTPKIVMFTIDTGEAPKGQDMEKAAHQNNLEEMISELAVA

Parental  MTAVKHEQEYMEV-RERIHRAINDNTNSRVVLWSSLKL-FVLVAMTLGQIYYLKRFFEVRRVV
          MTA.KH.QEYME..RERIH.AIN.NTNSRVVLW.SLKL..VLVAMTLGQIYYLK.FFEV.R..
Retrocopy MTAGKHKQEYMEI<RERIHGAINNNTNSRVVLW-SLKL<LVLVAMTLGQIYYLKSFFEVQRLI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.45 RPM	74.74 RPM
SRP007412_brain_prefrontal_cortex	0.24 RPM	54.50 RPM
SRP007412_cerebellum	1.55 RPM	66.77 RPM
SRP007412_heart	0.65 RPM	76.02 RPM
SRP007412_kidney	1.06 RPM	98.82 RPM
SRP007412_liver	0.59 RPM	86.49 RPM
SRP007412_testis	0.98 RPM	35.58 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_613 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_613 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_613 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 26 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000015262	2 retrocopies	retro_amel_1923, retro_amel_337,
Bos taurus	ENSBTAG00000039630	2 retrocopies	retro_btau_52, retro_btau_819,
Choloepus hoffmanni	ENSCHOG00000012728	6 retrocopies	retro_chof_104, retro_chof_1277, retro_chof_2323, retro_chof_2601, retro_chof_2709, retro_chof_981,
Callithrix jacchus	ENSCJAG00000020466	1 retrocopy	retro_cjac_1392,
Echinops telfairi	ENSETEG00000000556	2 retrocopies	retro_etel_2109, retro_etel_2154,
Homo sapiens	ENSG00000086598	1 retrocopy	retro_hsap_2793,
Gorilla gorilla	ENSGGOG00000028536	1 retrocopy	retro_ggor_1943,
Macaca mulatta	ENSMMUG00000031491	2 retrocopies	retro_mmul_1439, retro_mmul_613 ,
Mustela putorius furo	ENSMPUG00000001598	1 retrocopy	retro_mputfur_1241,
Mus musculus	ENSMUSG00000029390	2 retrocopies	retro_mmus_1361, retro_mmus_3262,
Nomascus leucogenys	ENSNLEG00000001652	2 retrocopies	retro_nleu_2454, retro_nleu_2794,
Otolemur garnettii	ENSOGAG00000009192	1 retrocopy	retro_ogar_2548,
Pongo abelii	ENSPPYG00000005090	3 retrocopies	retro_pabe_1919, retro_pabe_2227, retro_pabe_3597,