RetrogeneDB ID: retro_mmus_633

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 10:31413814..31414165(-)
• Located in intron of: ENSMUSG00000000296

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Supt4a
• Ensembl ID: ENSMUSG00000020485
• Aliases: Supt4a, AL022777, Supt4h, Supt4h1, Supt4h1a
• Description: suppressor of Ty 4A [Source:MGI Symbol;Acc:MGI:107416]

Sequence

>retro_mmus_633
ATGGCCCTGGAGACGGTACCGAAGGACCTGCGGCATCTGCGGGCTTGTTTGCTGTGCTCGTTAGTCAAGACTATAGACCA
GTTTGAATATGATGGGTGTGACAATTGCGATGCATACCTACAAATGAAGGGCAACAGAGAGATGGTTTATGACTGCACCA
GCTCTTCATTTGATGGAATCAATGCGATGATGAGTCCAGAGGACAGCTGGGTCTCCAAGTGGCAGCGAGTCAGTAACTTT
AAGCCAGGTGTATATGCTGTGTCCGTCACTGGTCGCCTGCCCCAAGGAATCGTGCGGGAGCTGAAAAGTCGAGGAGTGGC
CTACAAATCCAGAGACACAGCAATAAAGACC

Alignment

ORF - retro_mmus_633 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 99.15 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPEDSW
          MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGI.AMMSPEDSW
Retrocopy MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGINAMMSPEDSW

Parental  VSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
          VSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
Retrocopy VSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.09 RPM	16.96 RPM
SRP007412_cerebellum	0.04 RPM	17.85 RPM
SRP007412_heart	0.16 RPM	12.89 RPM
SRP007412_kidney	0.12 RPM	20.79 RPM
SRP007412_liver	0.03 RPM	14.47 RPM
SRP007412_testis	0.05 RPM	11.98 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_633 was not detected

EST

No EST(s) were mapped for retro_mmus_633 retrocopy.

TSS

No TSS is located nearby retro_mmus_633 retrocopy 5' end.

Lab

retro_mmus_633 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_633 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000017524	2 retrocopies	retro_cfam_1399, retro_cfam_553,
Homo sapiens	ENSG00000213246	2 retrocopies	retro_hsap_1081, retro_hsap_2280,
Gorilla gorilla	ENSGGOG00000007232	2 retrocopies	retro_ggor_1693, retro_ggor_854,
Macropus eugenii	ENSMEUG00000010164	1 retrocopy	retro_meug_2079,
Myotis lucifugus	ENSMLUG00000025583	1 retrocopy	retro_mluc_761,
Macaca mulatta	ENSMMUG00000007579	2 retrocopies	retro_mmul_1005, retro_mmul_842,
Mus musculus	ENSMUSG00000020485	2 retrocopies	retro_mmus_2857, retro_mmus_633 ,
Nomascus leucogenys	ENSNLEG00000008159	3 retrocopies	retro_nleu_1619, retro_nleu_1962, retro_nleu_2714,
Oryctolagus cuniculus	ENSOCUG00000025823	2 retrocopies	retro_ocun_1613, retro_ocun_1636,
Pongo abelii	ENSPPYG00000008233	1 retrocopy	retro_pabe_1940,
Pan troglodytes	ENSPTRG00000009451	2 retrocopies	retro_ptro_1614, retro_ptro_735,
Pteropus vampyrus	ENSPVAG00000002320	1 retrocopy	retro_pvam_477,
Rattus norvegicus	ENSRNOG00000007845	3 retrocopies	retro_rnor_1255, retro_rnor_1973, retro_rnor_556,