RetrogeneDB ID: retro_ocun_399

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: 1:148039458..148039777(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ARL1
• Ensembl ID: ENSOCUG00000002217
• Aliases: None
• Description: ADP-ribosylation factor-like 1 [Source:HGNC Symbol;Acc:692]

Sequence

>retro_ocun_399
GTGACATGAAAAAACCCTAAATTCCAAGTTCTGAGGATTTTAAGACAAACAAGAGTCCATGCCACACTGGAGATACTATT
CAAAACATAATGGCAGTGATTTACGTAGTACACAGTTGTGACTGAGAGTGACCCTGCAATTTCCAAATCCAGAATTAGTT
CCTATGTTGGCTGAAAAAGAGCTGAGAAATCCCACTTCAGTAGTGTTTGTGAATAAGCAGGATAGGTAGCAGGCCATGCC
ACTCTCAGAGATCGCAAAGTCATCACACACGTGACCTGCCTCCATGGACCGAAAGTGGAAAATATTCAAAACGTCCAGC

Alignment

ORF - retro_ocun_399 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.18 %
• Parental protein coverage: 55.56 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  VTYKNLKFQVWDLGGQTSIR-PYWRCYYS-NTDAVIYVVDSCD-RDRIGISKS-ELVAMLEEEELRKAIL
          VT.KN.KFQV.....QT....P.WR.YYS.N..AVIYVV.SCD......ISKS.ELV.ML.E.ELR....
Retrocopy VT*KNPKFQVLRILRQTRVH>PHWR-YYS>NIMAVIYVVHSCD>ESDPAISKS>ELVPMLAEKELRNPTS

Parental  VVFANKQDMEQAMTPSEMANSLGL-PALKDRKWQIFKTSA
          VVF.NKQD..QAM..SE.A.S....PA..DRKW.IFKTS.
Retrocopy VVFVNKQDR*QAMPLSEIAKSSHT*PASMDRKWKIFKTSS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	29.08 RPM
SRP017611_kidney	0.00 RPM	28.99 RPM
SRP017611_liver	0.00 RPM	6.55 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_399 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_399 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_399 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016452	2 retrocopies	retro_amel_1138, retro_amel_713,
Canis familiaris	ENSCAFG00000006992	2 retrocopies	retro_cfam_1176, retro_cfam_709,
Callithrix jacchus	ENSCJAG00000001966	1 retrocopy	retro_cjac_2938,
Echinops telfairi	ENSETEG00000020310	1 retrocopy	retro_etel_1850,
Macropus eugenii	ENSMEUG00000015525	1 retrocopy	retro_meug_518,
Myotis lucifugus	ENSMLUG00000002351	1 retrocopy	retro_mluc_255,
Monodelphis domestica	ENSMODG00000003056	1 retrocopy	retro_mdom_677,
Mustela putorius furo	ENSMPUG00000011822	1 retrocopy	retro_mputfur_1458,
Mus musculus	ENSMUSG00000060904	1 retrocopy	retro_mmus_3285,
Oryctolagus cuniculus	ENSOCUG00000002217	5 retrocopies	retro_ocun_1608, retro_ocun_399 , retro_ocun_400, retro_ocun_465, retro_ocun_847,
Oryctolagus cuniculus	ENSOCUG00000014876	1 retrocopy	retro_ocun_79,
Oryctolagus cuniculus	ENSOCUG00000029293	1 retrocopy	retro_ocun_611,
Otolemur garnettii	ENSOGAG00000015144	1 retrocopy	retro_ogar_1239,
Pteropus vampyrus	ENSPVAG00000008119	2 retrocopies	retro_pvam_1072, retro_pvam_715,
Rattus norvegicus	ENSRNOG00000005763	1 retrocopy	retro_rnor_2375,
Sorex araneus	ENSSARG00000013944	4 retrocopies	retro_sara_237, retro_sara_304, retro_sara_479, retro_sara_71,
Sarcophilus harrisii	ENSSHAG00000004634	2 retrocopies	retro_shar_204, retro_shar_275,
Ictidomys tridecemlineatus	ENSSTOG00000016022	2 retrocopies	retro_itri_1000, retro_itri_348,
Tarsius syrichta	ENSTSYG00000013257	5 retrocopies	retro_tsyr_1803, retro_tsyr_188, retro_tsyr_350, retro_tsyr_369, retro_tsyr_809,
Tursiops truncatus	ENSTTRG00000017202	1 retrocopy	retro_ttru_701,