RetrogeneDB ID: retro_ptro_2590

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 7:160799962..160800455(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CTDSP2
• Ensembl ID: ENSPTRG00000005155
• Aliases: None
• Description: None

Sequence

>retro_ptro_2590
ATGGAACAAGGCTCCATCATCACCCAGGCATGGAGGGAAGATGCCCTGGTCCTTACCAAGCAAGGCCTGGTTTCCAAAGT
CCTCTCTGAAGAGGCCTCATGTTTGTCACATCTTAAAAGTCCCCTTTCTGCTGTTCTTGCACCCAGCATGTTGGACAGTC
AAGTTCCCCCGCTGAGCAATCCACACATAAGGAGGGAGTCAACACCATTGCTATGTCGGATCAGCTCCAGCGTCTCCATT
ATCAGTTTTATCAGATCCCAGGAACCTGCCTGCTCCCAGAGGTGACAGAGAAAAATCAAGGAAGGATCTGTATGGTCACT
GACCTGGATGAAACCCTTGTGCATAGCTCCTTTAAGTCAATCAGCAATGCTGACTGCCTAGTGCCTGTAGAGCTTGGGGG
ACCATGCACCAGATCCATGTGCTCATGCGGCCTTATATGGATGAGTTCCTGACATGAATGGAGGAAATGTTTAAATGTGT
TTTCTTCATTGCT

Alignment

ORF - retro_ptro_2590 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.86 %
• Parental protein coverage: 60.52 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MEHGSIITQARREDALVLTKQGLVSK-SSPKKPRGRNIFK-ALFCCFRAQHVGQSSSSTELAAYKEEANT
          ME.GSIITQA.REDALVLTKQGLVSK.SS.K.P....I.K...FCC...QHVGQSSS..E....KE..NT
Retrocopy MEQGSIITQAWREDALVLTKQGLVSK>SSLKRPHVCHILK>SPFCCSCTQHVGQSSSPAEQSTHKEGVNT

Parental  IAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIE-GTTHQ
          IA.SD.LQ.L.YQFYQIPGTCLLPEVTE..QGRIC.V.DLDETLVHSSFK.I.NAD..VP.E...GT.HQ
Retrocopy IAMSDQLQRLHYQFYQIPGTCLLPEVTEKNQGRICMVTDLDETLVHSSFKSISNADCLVPVELG<GTMHQ

Parental  VYVLKRPYVDEFLRRMGELFECVLFTA
          ..VL.RPY.DEFL..M.E.F.CV.F.A
Retrocopy IHVLMRPYMDEFLT*MEEMFKCVFFIA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	90.27 RPM
SRP007412_cerebellum	0.00 RPM	165.73 RPM
SRP007412_heart	0.00 RPM	88.66 RPM
SRP007412_kidney	0.00 RPM	227.94 RPM
SRP007412_liver	0.00 RPM	101.87 RPM
SRP007412_testis	0.00 RPM	63.23 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_2590 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_2590 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_2590 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000006503	2 retrocopies	retro_cjac_3087, retro_cjac_919,
Homo sapiens	ENSG00000175215	2 retrocopies	retro_hsap_4315, retro_hsap_4319,
Macaca mulatta	ENSMMUG00000005321	2 retrocopies	retro_mmul_2208, retro_mmul_764,
Mus musculus	ENSMUSG00000078429	1 retrocopy	retro_mmus_612,
Nomascus leucogenys	ENSNLEG00000017164	2 retrocopies	retro_nleu_1741, retro_nleu_3079,
Petromyzon marinus	ENSPMAG00000009544	2 retrocopies	retro_pmar_20, retro_pmar_27,
Pongo abelii	ENSPPYG00000004711	14 retrocopies	retro_pabe_1708, retro_pabe_1739, retro_pabe_1740, retro_pabe_1742, retro_pabe_1746, retro_pabe_1762, retro_pabe_2402, retro_pabe_2592, retro_pabe_3202, retro_pabe_3205, retro_pabe_3221, retro_pabe_3237, retro_pabe_3554, retro_pabe_3578,
Pan troglodytes	ENSPTRG00000005155	7 retrocopies	retro_ptro_2587, retro_ptro_2589, retro_ptro_2590 , retro_ptro_2592, retro_ptro_2594, retro_ptro_2958, retro_ptro_3054,