RetrogeneDB ID: retro_btau_1493

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 6:58734003..58734387(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: LAPTM4B
• Ensembl ID: ENSBTAG00000016959
• Aliases: None
• Description: lysosomal-associated transmembrane protein 4B [Source:RefSeq peptide;Acc:NP_991371]

Sequence

>retro_btau_1493
ATGAAGATGGTGGCCCCCTGGATGCCGTTCTACTCCACCAGCTGCTGCCTGTGCTGCCATGTCCCAGCTGGCACCATCCT
GCTGGGCACCTGGGACCTGATCTTCAATGCTGTGGTACTGCTGGTTCTGTTGAGTGCCCTGGCTAATCCAGATCAGTATC
AGTCTTCAAATTCTGAACTCGGAGGTGGCTTTGAGTTCATGGATGATGCCAACATGTGCATTGCCATCACAATTTCTGTT
CTCACGGTCCTTAACTGGGCAATGGCTGTGCACGGAGCATACAAGCAACATGTGACCAGGATCATCCCATTCTTCTGTTA
CCAGATCTTTGGTTTTGCCCTGAACACTGTGGTTGCAGTTTATCCAAATTCCATCCAGGAATAC

Alignment

ORF - retro_btau_1493 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.76 %
• Parental protein coverage: 58.41 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MKMVAPWTRFYSNSCCLCCHVRTGTILLGVWYLILNAVVLLILLSALADPDHYHFSSSELGGDFEFMDDA
          MKMVAPW..FYS.SCCLCCHV..GTILLG.W.LI.NAVVLL.LLSALA.PD.Y..S.SELGG.FEFMDDA
Retrocopy MKMVAPWMPFYSTSCCLCCHVPAGTILLGTWDLIFNAVVLLVLLSALANPDQYQSSNSELGGGFEFMDDA

Parental  NMCIAIAISVLMILICAMATYGAYKQRAAWIIPFFCYQIFDFALNTLVAVTVLVYPNSIQEY
          NMCIAI.ISVL..L..AMA..GAYKQ....IIPFFCYQIF.FALNT.VAV....YPNSIQEY
Retrocopy NMCIAITISVLTVLNWAMAVHGAYKQHVTRIIPFFCYQIFGFALNTVVAV----YPNSIQEY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	148.23 RPM
ERP005899_muscle	0.00 RPM	342.92 RPM
SRP017611_brain	0.00 RPM	33.16 RPM
SRP017611_kidney	0.00 RPM	114.87 RPM
SRP017611_liver	0.00 RPM	212.03 RPM
SRP030211_testis	0.00 RPM	118.98 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1493 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1493 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1493 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000016959	3 retrocopies	retro_btau_1493 , retro_btau_1759, retro_btau_786,
Bos taurus	ENSBTAG00000020894	1 retrocopy	retro_btau_575,
Callithrix jacchus	ENSCJAG00000031235	3 retrocopies	retro_cjac_1368, retro_cjac_1664, retro_cjac_3027,
Myotis lucifugus	ENSMLUG00000003618	1 retrocopy	retro_mluc_1182,
Macaca mulatta	ENSMMUG00000008926	1 retrocopy	retro_mmul_532,
Mus musculus	ENSMUSG00000022257	1 retrocopy	retro_mmus_1549,
Nomascus leucogenys	ENSNLEG00000003756	1 retrocopy	retro_nleu_1531,
Oryctolagus cuniculus	ENSOCUG00000013689	1 retrocopy	retro_ocun_627,
Otolemur garnettii	ENSOGAG00000000512	3 retrocopies	retro_ogar_1977, retro_ogar_2856, retro_ogar_2902,
Pongo abelii	ENSPPYG00000018771	2 retrocopies	retro_pabe_2311, retro_pabe_279,
Pan troglodytes	ENSPTRG00000020448	1 retrocopy	retro_ptro_546,
Tursiops truncatus	ENSTTRG00000003124	1 retrocopy	retro_ttru_76,