RetrogeneDB ID: retro_btau_1727

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: X:5359861..5360489(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PRELID1
• Ensembl ID: ENSBTAG00000005009
• Aliases: PRELID1, PX19
• Description: PRELI domain-containing protein 1, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q32KN9]

Sequence

>retro_btau_1727
ATGGTGGAGTATTTCTTGGGCCAGAGCATGCTCTGGAGTTCGTGGGAGCAAGTGTTTGCTGCCTTCTGGCAGTGGTCCCA
AATCCCTGTAGTAAACATGCCTTGATGCAAGACATAGTGCACCGAGAGGTGACCTCTGACCAGAAGCTCCTGTCCGAGGA
CTCCTGACCAAGATGAATAGGATGCCCCGCTGGGCTGAGCAACTGTTTCTTGCCAGTGTTGCTCACTCAGTGTACATCCT
GGAAGATTCTATTGTGGACCCATGAAACCAAACCATGGCCACCTTCATCTGGAACATCAACCATACCCAGCTGATGGTGG
TGGAGGAATGATGTGTTTACTGTGTGAACTCTGACAACAGTGGCTGGACTGAAATCTGCCAGGAAACCTGGGTCTCCTCT
GGCTTATTTGGCATCTCCAGAGATGTTCAGGAATTTGGTCTTGCATGGTTCAAAAGCAACATGACCATGACTATGAAAGG
TTTTGAATACATCTTGGCCAAGCTGCAAGGTGAGGCTCCTCCCAAAACCCTTGGTGAAACAGCCAAGGAAGCCAAGGAGA
AGGCCAAGGAGATGGCAGTGGCAGCTACGGAGAATGCCAAGGACCTTGCCAGCAAGGCAGCCACCAAG

Alignment

ORF - retro_btau_1727 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.55 %
• Parental protein coverage: 95.89 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MVKYFLGQSVLRSSWDQVFAAFWQR-YPNPYSKHVLTEDIVHREVTSDQKLLS-RRLLTKTNRMPRWAER
          MV.YFLGQS.L.SSW.QVFAAFWQ...PNP.SKH.L..DIVHREVTSDQKLLS.R.LLTK.NRMPRWAE.
Retrocopy MVEYFLGQSMLWSSWEQVFAAFWQW<VPNPCSKHALMQDIVHREVTSDQKLLS<RGLLTKMNRMPRWAEQ

Parental  LFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHARLMVVEERCVYRVNSDNSGWTEIRREAWVSSSLFG
          LF.A.VAHSVYILEDSIVDP.NQTM.TF.WNINH..LMVVEE.CVY.VNSDNSGWTEI..E.WVSS.LFG
Retrocopy LFLASVAHSVYILEDSIVDP*NQTMATFIWNINHTQLMVVEE*CVYCVNSDNSGWTEICQETWVSSGLFG

Parental  VSRAVQEFGLARFKSNVTKTMKGFEYILAKLQGEAPPKTLVETAKEAKEKAKETALAATEKAKDLASKAA
          .SR.VQEFGLA.FKSN.T.TMKGFEYILAKLQGEAPPKTL.ETAKEAKEKAKE.A.AATE.AKDLASKAA
Retrocopy ISRDVQEFGLAWFKSNMTMTMKGFEYILAKLQGEAPPKTLGETAKEAKEKAKEMAVAATENAKDLASKAA

Parental  TK
          TK
Retrocopy TK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	40.30 RPM
ERP005899_muscle	0.00 RPM	234.38 RPM
SRP017611_brain	0.00 RPM	43.94 RPM
SRP017611_kidney	0.00 RPM	90.98 RPM
SRP017611_liver	0.00 RPM	74.30 RPM
SRP030211_testis	0.00 RPM	24.59 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1727 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1727 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1727 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 61 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005009	2 retrocopies	retro_btau_1727 , retro_btau_962,
Canis familiaris	ENSCAFG00000016443	2 retrocopies	retro_cfam_2055, retro_cfam_349,
Callithrix jacchus	ENSCJAG00000006953	5 retrocopies	retro_cjac_1131, retro_cjac_1689, retro_cjac_2401, retro_cjac_3359, retro_cjac_835,
Homo sapiens	ENSG00000169230	7 retrocopies	retro_hsap_1550, retro_hsap_2269, retro_hsap_249, retro_hsap_302, retro_hsap_3518, retro_hsap_3565, retro_hsap_579,
Gorilla gorilla	ENSGGOG00000011762	3 retrocopies	retro_ggor_2404, retro_ggor_302, retro_ggor_9,
Macropus eugenii	ENSMEUG00000001738	12 retrocopies	retro_meug_1194, retro_meug_1541, retro_meug_1618, retro_meug_1725, retro_meug_1726, retro_meug_2054, retro_meug_274, retro_meug_666, retro_meug_681, retro_meug_854, retro_meug_895, retro_meug_918,
Myotis lucifugus	ENSMLUG00000007008	2 retrocopies	retro_mluc_239, retro_mluc_64,
Macaca mulatta	ENSMMUG00000009046	2 retrocopies	retro_mmul_1822, retro_mmul_2457,
Monodelphis domestica	ENSMODG00000004804	3 retrocopies	retro_mdom_1529, retro_mdom_221, retro_mdom_596,
Mustela putorius furo	ENSMPUG00000012226	1 retrocopy	retro_mputfur_579,
Nomascus leucogenys	ENSNLEG00000012714	5 retrocopies	retro_nleu_1382, retro_nleu_2395, retro_nleu_2400, retro_nleu_803, retro_nleu_857,
Otolemur garnettii	ENSOGAG00000011455	4 retrocopies	retro_ogar_1352, retro_ogar_2025, retro_ogar_3006, retro_ogar_665,
Pongo abelii	ENSPPYG00000016086	7 retrocopies	retro_pabe_1283, retro_pabe_1696, retro_pabe_1699, retro_pabe_2907, retro_pabe_377, retro_pabe_409, retro_pabe_608,
Sus scrofa	ENSSSCG00000014042	4 retrocopies	retro_sscr_372, retro_sscr_794, retro_sscr_795, retro_sscr_811,
Tupaia belangeri	ENSTBEG00000006445	1 retrocopy	retro_tbel_3855,
Tursiops truncatus	ENSTTRG00000009571	1 retrocopy	retro_ttru_1886,