RetrogeneDB ID: retro_chof_70

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: GeneScaffold_1188:2507..2754(-)
• Located in intron of: ENSCHOG00000011429

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C6orf52
• Ensembl ID: ENSCHOG00000010768
• Aliases: None
• Description: chromosome 6 open reading frame 52 [Source:HGNC Symbol;Acc:20881]

Sequence

>retro_chof_70
AGCGGACACCACCTTCTTTTTGCATGTGAGATCGCTGGGCACCCAGCTAAGACGTCGATTACATCTGAGGGAACCACAGC
TCTGCCCGAAAACTGAGAGGAATGCGCCCGAGAAGATCCAAATCTTCACTTGCATGATGAGGGATTAAATAAGGAATTTA
TGGTGAAAGTGCAGAACTCTAGGACTCCTCGTGAGTTGCCCCAGGCAACCTCTGTATAGAATTCACTCAAAAATCCTAAA
TGAGACC

Alignment

ORF - retro_chof_70 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 61.18 %
• Parental protein coverage: 90.22 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  SGHSLLSVGDTPGHPAEASVESQGTTALPENQDEDPLEAPNLHLNIEELNKEFMVK-SEELYDS-LMACH
          SGH.LL......GHPA..S..S.GTTALPEN..E...E.PNLHL..E.LNKEFMVK.S.EL.DS.L..C.
Retrocopy SGHHLLFACEIAGHPAKTSITSEGTTALPEN*EECAREDPNLHLHDEGLNKEFMVK<SAEL*DS<LVSCP

Parental  WQPLDTIHSKIPDET
          .QPL..IHSKI..ET
Retrocopy RQPLYRIHSKILNET

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_70 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000002583	1 retrocopy	retro_amel_1114,
Canis familiaris	ENSCAFG00000030234	1 retrocopy	retro_cfam_1098,
Choloepus hoffmanni	ENSCHOG00000010768	2 retrocopies	retro_chof_2530, retro_chof_70 ,
Equus caballus	ENSECAG00000008229	2 retrocopies	retro_ecab_684, retro_ecab_792,
Monodelphis domestica	ENSMODG00000028324	12 retrocopies	retro_mdom_1372, retro_mdom_2019, retro_mdom_322, retro_mdom_336, retro_mdom_453, retro_mdom_492, retro_mdom_513, retro_mdom_523, retro_mdom_534, retro_mdom_616, retro_mdom_746, retro_mdom_894,
Tursiops truncatus	ENSTTRG00000003650	1 retrocopy	retro_ttru_927,
Vicugna pacos	ENSVPAG00000003001	2 retrocopies	retro_vpac_198, retro_vpac_609,