RetrogeneDB ID: retro_ggor_758

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:122693252..122694161(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000027158
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ENSG00000197849
• Ensembl ID: ENSGGOG00000023114
• Aliases: None
• Description: None

Sequence

>retro_ggor_758
AACTCTTCTGTGACAGAGTTTATCCTCGAAGGCTTAACCTACCAGCCAGGACTGCGGATCCCCCTCTTCTTCCTGTTTCT
GGGTTTCTACATGGTCACCGTGGTGGGGAACCTGGGCTTGATAACCCTGCTTGGGCTGAACTCTCACCTGCACACTCCCA
TGTACTTCTTCCTTTTTAACCTCTCTCTAATAGATTTCTGTTTCTCCACTACCATCACTCCCAAAATGCTGATGAGTTTT
GTCTCAAGGAAGAACATCATTTCCTTCATAGAGTGTATGACTCAGCTCTTTTTCTTCTGCTTCTTTGTCGTCTCTGAGTC
CTTCATCTTGTCAGCGATGGCGTAGGACCACTACATGGCCATCTGTAACCCACTGTTGTACATGGTCACCATGTCTTGCC
AGGTGTGTTTGCTCCTTTTGTTGGGTGCCTATGGGATGGGGTTTGCTGGGGCCATGGCCCACACAGGAAGCATAATGAAC
CTGACCTTCTGTGCTGACAACCTTGTCAATCATTTCATGTGTGACATCCTTCCTCTCCTTGAGCTCTCCTGCAACAGCTC
TTACATGAATGAGCTGGTGGTCTTTATTGTGGTGGCTGTTGACGTTGGAATGCCCATTGTCACTGTCTTTATTTCTTATG
CCCTCATCCTCTCCAGCATTCTACACAGCAGTTCTACAGAAGGCAGGTCCAAAGCCTTTAGTACTTGCAGTTCCCACATA
ATTGTAGTTTCTCTTTTCTTTGGTTCTGGTGCTTTCATGTATCTCAAACCCCTTTCCATCCTGCCCCTCGAGCAAGGGAA
AGTGTCCTCCCTGTTCTATACCATAATAGTCCCCATGTTAAACCCATTAATCTATAGCTTGAGGAACAAGGATGTCAAAG
TTGCCCTGAGGAGAACTTTGGGCAGAAAA

Alignment

ORF - retro_ggor_758 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 61.06 %
• Parental protein coverage: 97.43 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  NSSVTEFILAGLSEQPELQLPLFLLFLGIYVVTVVGNLGMTTLIWLSSHLHTPMYYFLSSLSFIDFCHST
          NSSVTEFIL.GL..QP.L..PLF.LFLG.Y.VTVVGNLG..TL..L.SHLHTPMY.FL..LS.IDFC.ST
Retrocopy NSSVTEFILEGLTYQPGLRIPLFFLFLGFYMVTVVGNLGLITLLGLNSHLHTPMYFFLFNLSLIDFCFST

Parental  VITPKMLVNFVTEKNIIFYPECMTQLYFFLIFAIAECHMLAAMAYDRYMAICSPLLYSVIISNKACFSLI
          .ITPKML..FV..KNII...ECMTQL.FF..F...E...L.AMA.D.YMAIC.PLLY.V..S...C..L.
Retrocopy TITPKMLMSFVSRKNIISFIECMTQLFFFCFFVVSESFILSAMA*DHYMAICNPLLYMVTMSCQVCLLLL

Parental  LGVYIIGLVCASVHTGCMFRVQFCKFDVINHYFCDLLPLLKLSCSSIYVNKLLILCVGAFNILVPSLTIL
          LG.Y..G...A..HTG......FC.....NH..CD.LPLL.LSC.S.Y.N.L....V.A.....P..T..
Retrocopy LGAYGMGFAGAMAHTGSIMNLTFCADNLVNHFMCDILPLLELSCNSSYMNELVVFIVVAVDVGMPIVTVF

Parental  CSYIFIIASILHIRSTEGRSKAFSTCSSHMLAVVIFFGSAAFMYLQPSSVSSMDQGKVSSVFYTIVVPML
          .SY..I..SILH..STEGRSKAFSTCSSH...V..FFGS.AFMYL.P.S.....QGKVSS.FYTI.VPML
Retrocopy ISYALILSSILHSSSTEGRSKAFSTCSSHIIVVSLFFGSGAFMYLKPLSILPLEQGKVSSLFYTIIVPML

Parental  NPLIYSLRNKDVHVALKKMLGKR
          NPLIYSLRNKDV.VAL...LG..
Retrocopy NPLIYSLRNKDVKVALRRTLGRK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.10 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_758 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_758 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 2 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000023114	6 retrocopies	retro_ggor_682, retro_ggor_683, retro_ggor_684, retro_ggor_756, retro_ggor_757, retro_ggor_758 ,
Macropus eugenii	ENSMEUG00000013370	4 retrocopies	retro_meug_2060, retro_meug_2076, retro_meug_35, retro_meug_447,