RetrogeneDB ID: retro_mdom_323

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 1:135550241..135550788(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C1orf43
• Ensembl ID: ENSMODG00000017237
• Aliases: None
• Description: chromosome 1 open reading frame 43 [Source:HGNC Symbol;Acc:29876]

Sequence

>retro_mdom_323
ATGGCATTCAGCAGTAACTGGTTGTCCAGGCTGAATGTAGTGCTGGTGAAGACCTATGGGAGCTTGGTATTTGTGGTGTT
GTTCATTTTTGTGAAGAAGCAGATAATGTGTTTTGCTATAAAGTCTTAAAGAGGCCTGCATGTCCCTATGGGGCACAACA
CTCCTAAGGATCTGAAGGAAGACGTTGGCATCCAACTATCCAAGGTTCATGATGTAATGTATGAACCTCAGCTTCTTGAA
GAGGATGAAGACAGACTTTTACAATTATAGACACTGGGAAATCAACATTGCTACAACTACCTGCACAGAATGAAAGCATT
TGATGCCATTTATGCCACTGAGATCCCATTCCATTCAGAATACTGGCATCCCCATTCCTTGATGGGCAAGAATTTCTAAT
CATAACTGCTGGAGCTTTGAAACACAAGTACTCCCTTCAAGGATGTCCGAAAGGCCCTCACTGATACCCTGTTATATAGT
TATGAGACAGCTCGATATGGAACTGAAGTCTTTGGCCAGATGGAGTTTTCTACATTATCAGGAAGCA

Alignment

ORF - retro_mdom_323 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 77.05 %
• Parental protein coverage: 71.65 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MASSSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGHNAPKDLKEEIDIRLSKVQ
          MA.SSNWLS..NVVLV..YGSLVFV.LFIFVK.QIM.FA.KS.RG.HVP.GHN.PKDLKE...I.LSKV.
Retrocopy MAFSSNWLSRLNVVLVKTYGSLVFVVLFIFVKKQIMCFAIKS*RGLHVPMGHNTPKDLKEDVGIQLSKVH

Parental  DVKYEPKLLEEDDARLLQLETPGNQHCYNYLYRMKALDAIRASEIPFHSEGRHPRSLMGKNFRSYLLELR
          DV.YEP.LLEED..RLLQL.T.GNQHCYNYL.RMKA.DAI.A.EIPFHSE..HP.SLMGKNF.S.LLEL.
Retrocopy DVMYEPQLLEEDEDRLLQL*TLGNQHCYNYLHRMKAFDAIYATEIPFHSEYWHPHSLMGKNF*S*LLEL*

Parental  NTSTPFKGVRKALIDTLLDGYETARYGTGVFGQTE-YLHYQEA
          NTSTPFK.VRKAL.DTLL..YETARYGT.VFGQ.E..LHYQEA
Retrocopy NTSTPFKDVRKALTDTLLYSYETARYGTEVFGQME>FLHYQEA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_323 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_323 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000011865	1 retrocopy	retro_amel_190,
Callithrix jacchus	ENSCJAG00000009722	1 retrocopy	retro_cjac_175,
Dasypus novemcinctus	ENSDNOG00000019160	1 retrocopy	retro_dnov_2515,
Dipodomys ordii	ENSDORG00000005454	1 retrocopy	retro_dord_190,
Equus caballus	ENSECAG00000017585	2 retrocopies	retro_ecab_618, retro_ecab_814,
Echinops telfairi	ENSETEG00000001056	15 retrocopies	retro_etel_1138, retro_etel_1318, retro_etel_1388, retro_etel_1633, retro_etel_2182, retro_etel_2205, retro_etel_2206, retro_etel_394, retro_etel_651, retro_etel_719, retro_etel_720, retro_etel_773, retro_etel_842, retro_etel_957, retro_etel_981,
Macropus eugenii	ENSMEUG00000002600	6 retrocopies	retro_meug_1149, retro_meug_1298, retro_meug_1439, retro_meug_1637, retro_meug_213, retro_meug_69,
Myotis lucifugus	ENSMLUG00000013338	1 retrocopy	retro_mluc_537,
Monodelphis domestica	ENSMODG00000017237	3 retrocopies	retro_mdom_1283, retro_mdom_2003, retro_mdom_323 ,
Mus musculus	ENSMUSG00000027942	6 retrocopies	retro_mmus_1014, retro_mmus_1018, retro_mmus_1020, retro_mmus_1107, retro_mmus_1792, retro_mmus_490,
Otolemur garnettii	ENSOGAG00000012008	2 retrocopies	retro_ogar_2563, retro_ogar_38,
Ochotona princeps	ENSOPRG00000007244	2 retrocopies	retro_opri_426, retro_opri_586,
Pongo abelii	ENSPPYG00000000785	2 retrocopies	retro_pabe_3590, retro_pabe_969,
Pteropus vampyrus	ENSPVAG00000002717	1 retrocopy	retro_pvam_696,
Rattus norvegicus	ENSRNOG00000017758	1 retrocopy	retro_rnor_139,
Sarcophilus harrisii	ENSSHAG00000012915	1 retrocopy	retro_shar_740,
Tupaia belangeri	ENSTBEG00000013866	1 retrocopy	retro_tbel_177,
Tarsius syrichta	ENSTSYG00000012777	1 retrocopy	retro_tsyr_91,
Tursiops truncatus	ENSTTRG00000015824	1 retrocopy	retro_ttru_923,