RetrogeneDB ID: retro_pabe_2441

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 4:76342431..76342719(+)
• Located in intron of: ENSPPYG00000014821

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSPPYG00000029838
• Aliases: None
• Description: None

Sequence

>retro_pabe_2441
ATGAGCGAGTTGAGCTTGAAGTCCAGCCAGCCCTCGGCCTCCAAGCAGGAAATGGACAGCACTGAGAAGCGGGGCCGGGG
CAGGCCCCACAAGCAGCCTCCGGTGAGTCCCGGGACAGCAATGGTAGGGAGTCAGAAGGAGCCTAGTGAAGTGCCAACAA
CTAAGAGACCTTGGGGCCAACCAAAGGGAAGCAAAAACAAGGGAGCTGCCAAGACCCGGAAAACCACCACAACTCCAGGA
AGGAAACCAAGGGGCAGACCCAGAAAACTGGAGAAGGAGGAAGAGGAG

Alignment

ORF - retro_pabe_2441 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 84.38 %
• Parental protein coverage: 92.31 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAA
          MSE.S.KSSQP.ASKQE.D.TEKRGRGRP.KQPPVSPGTA.VGSQKEPSEVPT.KRP.G.PKGSKNKGAA
Retrocopy MSELSLKSSQPSASKQEMDSTEKRGRGRPHKQPPVSPGTAMVGSQKEPSEVPTTKRPWGQPKGSKNKGAA

Parental  KTRKTTTTPGRKPRGRPKKLVGEEAD
          KTRKTTTTPGRKPRGRP.KL..EE..
Retrocopy KTRKTTTTPGRKPRGRPRKLEKEEEE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.39 RPM	4.15 RPM
SRP007412_cerebellum	0.61 RPM	0.97 RPM
SRP007412_heart	0.15 RPM	0.51 RPM
SRP007412_kidney	0.80 RPM	0.96 RPM
SRP007412_liver	0.43 RPM	0.28 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_2441 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_2441 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_2441 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pan troglodytes	retro_ptro_2053

---

Parental genes homology:

Parental genes homology involve 12 parental genes, and 26 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001061	1 retrocopy	retro_amel_1637,
Callithrix jacchus	ENSCJAG00000015226	2 retrocopies	retro_cjac_1197, retro_cjac_3158,
Homo sapiens	ENSG00000137309	4 retrocopies	retro_hsap_1175, retro_hsap_2277, retro_hsap_4663, retro_hsap_695,
Myotis lucifugus	ENSMLUG00000010085	2 retrocopies	retro_mluc_1619, retro_mluc_2429,
Macaca mulatta	ENSMMUG00000019529	2 retrocopies	retro_mmul_1276, retro_mmul_2406,
Mus musculus	ENSMUSG00000046711	1 retrocopy	retro_mmus_188,
Nomascus leucogenys	ENSNLEG00000008303	1 retrocopy	retro_nleu_1097,
Procavia capensis	ENSPCAG00000016076	1 retrocopy	retro_pcap_236,
Pongo abelii	ENSPPYG00000029838	4 retrocopies	retro_pabe_1941, retro_pabe_2441 , retro_pabe_3623, retro_pabe_960,
Pan troglodytes	ENSPTRG00000040884	6 retrocopies	retro_ptro_1611, retro_ptro_2053, retro_ptro_3098, retro_ptro_499, retro_ptro_789, retro_ptro_807,
Pteropus vampyrus	ENSPVAG00000014283	1 retrocopy	retro_pvam_116,
Rattus norvegicus	ENSRNOG00000000488	1 retrocopy	retro_rnor_164,