RetrogeneDB ID:

retro_ptro_3159

Retrocopy
location
Organism:Chimpanzee (Pan troglodytes)
Coordinates:X:116313542..116314837(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:EEF1G
Ensembl ID:ENSPTRG00000003768
Aliases:None
Description:eukaryotic translation elongation factor 1 gamma [Source:HGNC Symbol;Acc:3213]


Retrocopy-Parental alignment summary:






>retro_ptro_3159
ACCCTGTACACATATCCTGAAAACTGAAGGAACTTCAAGGCCCTCATTGCTGCTCAGCACAGAGGGGCTCAGGTCCGTGT
GCTCTCCGCACCACCCCATTTCCACTTTGGCCAAACCAACCGCACCCCTGAATTTCTCTGCAAATTTCCTGCTGGCAAGA
TTCCAGCATTTGAAGGTGACGATAGATTCTGTGTGTTTGAGAGCAATGCCATTGCCTACTATGTGAGCAATGAGGAGCTG
CAGGGAAGTACTCCAGAGGCAGCAGCCCAAGTGATGCAGTGGGTGAGCTTTGCTGATAGCAGTATAGTGTCCCCAGCCAG
TACCTGGGTGTTCCCCACCTTGGGCATCATGCATCACAACAAACAGGCCACTGAGAATACAAAGGAGGAAGTGAGGCAAA
TTCTGGGGCTGTTGGATGCTCACTTGAAGACAAGGACTTTTCTGGAGGGTGAACGAGTGACATTGACTGACATCACAGTT
GTCTGCACCCTATTGTGGCTCTATAAGCAGGTACTAGAACCTTCTTTCTGCCAGGCCTTTCCCAATACCAACCGCTGGTT
CCTCACCTGCATTAACCAGCCTCAGTTCTGCACTGTCTTGGGGAAAGCAAAACTATGTGAGAAGATGGCCCAGTCTGATG
CTAAAAAGTTTGTGGAAAGCCAGCCTAAAAAGGACACACCACGGGAAGAGAAGCGTTCACGGGAAGAGAAGCAGAAGCCC
CAGGCTGAGCAGGAGGAGAAAAAGGCGGCTGCCCCTACTCCTGAGGAGGAGATGGATGAATGTGAGCAGGCGCTGGCCGC
TGAGCCCAAGGCCAAGGACCCCTTTGCTCACCTGCCCAAGAGTACCTTTGTGTTGGATGAATTGAAGCTCAAGTACTCCA
ATGAGACACACTCTCTGTGGCACTGCCATATTTCTGGGAGCACTTTGATAAGGACGGCTGGTCCCTGTTGTACTCAGAGT
ATCGCTTCCCTGAAGAATTCACTCAGACCTTCATGAGCTGCAATCTCATCACTGGAATGTTCCAGTGACTGGACAAGCTG
AGGAAGAATGCCTTCGCCAGTGTCATCCTCTTTGGAACCAACAATATCAGCTCCATTTCTGGAGTCTGGGTCTTCCGAGG
CCAGGAGCTTGCCTTTCCACTGAGTCCAGATTGGCAGGTGGGCTATGAGTCATACACATGGCAGAAACTGGATCCTGGCA
GCGAGGAGACCCAGATGCTGTTTCGAGAGTACTTTTCCTGGGAGGGGGCCTTCTAGCATGTGGGCAAACCCTTCAATCAG
GGCAAGATCTTCAAG

ORF - retro_ptro_3159 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 90.32 %
Parental protein coverage: 88.91 %
Number of stop codons detected: 3
Number of frameshifts detected 1


Retrocopy - Parental Gene Alignment:

ParentalTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNA
TLYTYPEN.R.FKALIAAQ..GAQVRVLSAPPHFHFGQTNRTPEFL.KFPAGK.PAFEGDD.FCVFESNA
RetrocopyTLYTYPEN*RNFKALIAAQHRGAQVRVLSAPPHFHFGQTNRTPEFLCKFPAGKIPAFEGDDRFCVFESNA
ParentalIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDA
IAYYVSNEEL.GSTPEAAAQV.QWVSFADS.IV.PASTWVFPTLGIMHHNKQATEN.KEEVR.ILGLLDA
RetrocopyIAYYVSNEELQGSTPEAAAQVMQWVSFADSSIVSPASTWVFPTLGIMHHNKQATENTKEEVRQILGLLDA
ParentalYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMA
.LKTRTFL.GERVTL.DITVVCTLLWLYKQVLEPSF.QAFPNTNRWFLTCINQPQF..VLG..KLCEKMA
RetrocopyHLKTRTFLEGERVTLTDITVVCTLLWLYKQVLEPSFCQAFPNTNRWFLTCINQPQFCTVLGKAKLCEKMA
ParentalQFDAKKFAETQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLP
Q.DAKKF.E.QPKKDTPR.EK.SREEKQKPQAE..EEKKAAAP.PEEEMDECEQALAAEPKAKDPFAHLP
RetrocopyQSDAKKFVESQPKKDTPREEKRSREEKQKPQAE-QEEKKAAAPTPEEEMDECEQALAAEPKAKDPFAHLP
ParentalKSTFVLDEFKRKYSNE-DTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLR
KSTFVLDE.K.KYSNE.DTLSVALPYFWEHFDKDGWSL.YSEYRFPEE.TQTFMSCNLITGMFQ.LDKLR
RetrocopyKSTFVLDELKLKYSNE<DTLSVALPYFWEHFDKDGWSLLYSEYRFPEEFTQTFMSCNLITGMFQ*LDKLR
ParentalKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAF
KNAFASVILFGTNN.SSISGVWVFRGQELAFPLSPDWQV.YESYTW.KLDPGSEETQ.L.REYFSWEGAF
RetrocopyKNAFASVILFGTNNISSISGVWVFRGQELAFPLSPDWQVGYESYTWQKLDPGSEETQMLFREYFSWEGAF
ParentalQHVGKAFNQGKIFK
.HVGK.FNQGKIFK
Retrocopy*HVGKPFNQGKIFK

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .02 RPM 195 .55 RPM
SRP007412_cerebellum 0 .07 RPM 228 .07 RPM
SRP007412_heart 0 .03 RPM 290 .06 RPM
SRP007412_kidney 0 .08 RPM 641 .01 RPM
SRP007412_liver 0 .23 RPM 271 .89 RPM
SRP007412_testis 0 .11 RPM 237 .32 RPM
Pan troglodytes was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_ptro_3159 retrocopy.
Pan troglodytes was not studied using FANTOM5 data.
retro_ptro_3159 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ptro_3159 has 2 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Homo sapiens retro_hsap_4744
Pongo abelii retro_pabe_3690

Parental genes homology:
Parental genes homology involve 26 parental genes, and 69 retrocopies.

Species Parental gene accession Retrocopies number
Ailuropoda melanoleuca ENSAMEG000000067451 retrocopy
Bos taurus ENSBTAG000000118431 retrocopy
Canis familiaris ENSCAFG000000158346 retrocopies
Callithrix jacchus ENSCJAG000000189496 retrocopies
Equus caballus ENSECAG000000143341 retrocopy
Erinaceus europaeus ENSEEUG000000012311 retrocopy
Homo sapiens ENSG000002547724 retrocopies
Latimeria chalumnae ENSLACG000000147001 retrocopy
Loxodonta africana ENSLAFG000000033391 retrocopy
Myotis lucifugus ENSMLUG000000003421 retrocopy
Macaca mulatta ENSMMUG000000065985 retrocopies
Monodelphis domestica ENSMODG000000076911 retrocopy
Mustela putorius furoENSMPUG000000139422 retrocopies
Mus musculus ENSMUSG000000716447 retrocopies
Nomascus leucogenys ENSNLEG000000035282 retrocopies
Oryctolagus cuniculus ENSOCUG000000209593 retrocopies
Otolemur garnettii ENSOGAG000000008271 retrocopy
Ochotona princeps ENSOPRG000000145631 retrocopy
Pongo abelii ENSPPYG000000294345 retrocopies
Pan troglodytes ENSPTRG00000003768 3 retrocopies
retro_ptro_1879, retro_ptro_2017, retro_ptro_3159 ,
Pteropus vampyrus ENSPVAG000000034401 retrocopy
Rattus norvegicus ENSRNOG000000200758 retrocopies
Sorex araneus ENSSARG000000112321 retrocopy
Sus scrofa ENSSSCG000000130641 retrocopy
Ictidomys tridecemlineatus ENSSTOG000000028512 retrocopies
Tursiops truncatus ENSTTRG000000024593 retrocopies



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