RetrogeneDB ID: retro_ptro_910

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 14:48502098..48502635(+)
• Located in intron of: ENSPTRG00000006313

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RHOJ
• Ensembl ID: ENSPTRG00000006424
• Aliases: None
• Description: None

Sequence

>retro_ptro_910
ATGCTCAAGTGCGTGGTGGTCGGCGACGGGGCGGTGGGCAAGACGTGCCTACTCATGAGCTGTGCCAACGACGCCTTCCC
GGAGGAGTACGTGCCCACCGTCTTCGACCACTACACAGTCAGCGTCACCGTGGGGGGCAAGCAGTACCTCCTAGGACTCT
ATAACACGGCCGGACAGGAAGACTATGACCGTCTGAGGCCTTTATCTTACCCAATGACCGACGTCTTCCTTATATGCTTC
TCGGTGGTAAATCCAGCCTCATTTCAAAATGTGAGAGAGGAGTGGGTACCGGAACTTAAGGAATACGCACCAAATGTACC
CTTTTTATTAATAGGAGCTCAGATTGATCTCCGAGATGACCCCAAAACTTTAGCAAGACTGAGTAATATGAAAGAAAAAC
CTATATGTGTGGAACAAGGACAGAAACTAGCAAAAGAGATAGGAGCATGCTGCTATGTGGAATGTTCAGCTTTAACCCAG
AAGGGATTGAAGACTGTTTTTGATGAGGCTATCATAGCCATTTTAACTCCAAAGAAA

Alignment

ORF - retro_ptro_910 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.56 %
• Parental protein coverage: 83.64 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSY
          MLKCVVVGDGAVGKTCLLMS.ANDAFPEEYVPTVFDHY.V.VTVGGKQ.LLGLY.TAGQEDY..LRPLSY
Retrocopy MLKCVVVGDGAVGKTCLLMSCANDAFPEEYVPTVFDHYTVSVTVGGKQYLLGLYNTAGQEDYDRLRPLSY

Parental  PNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHG
          P.TDVFLICFSVVNPAS..NV.EEWVPELK...P.VP..LIG.QIDLRDDPKTLARL..MKEKP...E.G
Retrocopy PMTDVFLICFSVVNPASFQNVREEWVPELKEYAPNVPFLLIGAQIDLRDDPKTLARLSNMKEKPICVEQG

Parental  VKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKK
          .KLAK.IGA.CY.ECSALTQKGLK.VFDEAI..I..PKK
Retrocopy QKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.41 RPM	2.47 RPM
SRP007412_cerebellum	0.43 RPM	3.73 RPM
SRP007412_heart	0.44 RPM	9.65 RPM
SRP007412_kidney	0.42 RPM	6.01 RPM
SRP007412_liver	0.29 RPM	4.78 RPM
SRP007412_testis	0.53 RPM	2.32 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_910 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_910 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_910 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1333
Pongo abelii	retro_pabe_1107

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Dasypus novemcinctus	ENSDNOG00000001761	2 retrocopies	retro_dnov_192, retro_dnov_927,
Gorilla gorilla	ENSGGOG00000007948	1 retrocopy	retro_ggor_22,
Pan troglodytes	ENSPTRG00000006424	4 retrocopies	retro_ptro_1643, retro_ptro_2091, retro_ptro_2971, retro_ptro_910 ,
Pan troglodytes	ENSPTRG00000018910	4 retrocopies	retro_ptro_1288, retro_ptro_3044, retro_ptro_3274, retro_ptro_36,
Vicugna pacos	ENSVPAG00000004859	2 retrocopies	retro_vpac_574, retro_vpac_588,