RetrogeneDB ID: retro_ptro_957

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 14:20547899..20548506(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ARL6IP1
• Ensembl ID: ENSPTRG00000007824
• Aliases: None
• Description: ADP-ribosylation factor-like 6 interacting protein 1 [Source:HGNC Symbol;Acc:697]

Sequence

>retro_ptro_957
ATGGCAGAGGGAGGTAACCACGGCACCAATTTGCTGGCTGCAGAGACTGCAAGTTTAGAACAATAGCTGCAAGAATGGGG
AAAAGTGATGTTGATGGTGGATAAAGTCTTATTATGGGAAAGAGCTTGGTTTTCACCTGCCATCATGGACTTGGTTTCTT
TGGTGCTTCAATTATCTACTATCTAGATCCATCTGTTCTGTCTGCTGTTTCCTCTTTTGTTGTGTTTTGGTGCTTGGCTG
ACTACCTTGTTCCCATTCTAGCACCTAACATTTTTGGCTCCAATAAATGCACCAGCAATCAACAGCAAAAATTCCATGAA
ATTTGCAGCAATCTACTAAAAACTCAATGCAGAGCTATGGACTGGTGGAAACAAATCTTCGCACTGAAGGAAGAAAAGCC
TGAAATGTGTTTCATGGCCATGATCATTTATCTCGCTGCAGTTGTTTGGATGGGACAGCAAGTCCACAACCTGCTTCTCA
GCTACCTGATAGTGACTTTCTTACTGTTGCTTCCTCAACTAAACCAACACGGAATCATTTCAAACCACACTGGAAAGGCC
AAAGGGAGATAAACAAGCTTCTCGAACAAAAAGAAAAGAAAAATGAA

Alignment

ORF - retro_ptro_957 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.1 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFL-IIYYLDPSVLSG
          MAEG.N..TNLLAAETASLE..LQ.WG.VMLM.DKVL.WERAWF.PAIM..VSLV...IIYYLDPSVLS.
Retrocopy MAEGGNHGTNLLAAETASLEQ*LQEWGKVMLMVDKVLLWERAWFSPAIMDLVSLVLQ<IIYYLDPSVLSA

Parental  VSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFM
          VS.FV.F.CLADYLVPILAP.IFGSNK.T..QQQ.FHEICSNL.KT..RA..WWK..F.LKEEKP.M.FM
Retrocopy VSSFVVFWCLADYLVPILAPNIFGSNKCTSNQQQKFHEICSNLLKTQCRAMDWWKQIFALKEEKPEMCFM

Parental  TMIVSLAAVAWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAK-REINKLLKQKEKKNE
          .MI..LAAV.W.GQQVHNLLL.YLIVT.LLLLP.LNQHGII....G.AK.REINKLL.QKEKKNE
Retrocopy AMIIYLAAVVWMGQQVHNLLLSYLIVTFLLLLPQLNQHGIISNHTGKAK<REINKLLEQKEKKNE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	228.33 RPM
SRP007412_cerebellum	0.00 RPM	198.31 RPM
SRP007412_heart	0.00 RPM	18.71 RPM
SRP007412_kidney	0.00 RPM	76.70 RPM
SRP007412_liver	0.00 RPM	105.08 RPM
SRP007412_testis	1.05 RPM	131.94 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_957 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_957 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_957 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1393
Gorilla gorilla	retro_ggor_1080

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 69 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000018174	20 retrocopies	retro_cfam_114, retro_cfam_1204, retro_cfam_1232, retro_cfam_1261, retro_cfam_127, retro_cfam_1301, retro_cfam_1348, retro_cfam_1364, retro_cfam_1525, retro_cfam_1582, retro_cfam_1605, retro_cfam_1642, retro_cfam_1745, retro_cfam_1966, retro_cfam_21, retro_cfam_427, retro_cfam_464, retro_cfam_699, retro_cfam_831, retro_cfam_888,
Choloepus hoffmanni	ENSCHOG00000007800	5 retrocopies	retro_chof_1153, retro_chof_1320, retro_chof_2130, retro_chof_2284, retro_chof_270,
Callithrix jacchus	ENSCJAG00000020068	2 retrocopies	retro_cjac_782, retro_cjac_857,
Cavia porcellus	ENSCPOG00000012603	1 retrocopy	retro_cpor_291,
Erinaceus europaeus	ENSEEUG00000005434	1 retrocopy	retro_eeur_186,
Echinops telfairi	ENSETEG00000020152	2 retrocopies	retro_etel_2083, retro_etel_549,
Homo sapiens	ENSG00000170540	3 retrocopies	retro_hsap_1393, retro_hsap_559, retro_hsap_902,
Gorilla gorilla	ENSGGOG00000002902	3 retrocopies	retro_ggor_1080, retro_ggor_505, retro_ggor_729,
Loxodonta africana	ENSLAFG00000018632	2 retrocopies	retro_lafr_420, retro_lafr_741,
Macropus eugenii	ENSMEUG00000007896	1 retrocopy	retro_meug_1842,
Microcebus murinus	ENSMICG00000012246	5 retrocopies	retro_mmur_1383, retro_mmur_1561, retro_mmur_582, retro_mmur_939, retro_mmur_951,
Monodelphis domestica	ENSMODG00000005944	1 retrocopy	retro_mdom_794,
Nomascus leucogenys	ENSNLEG00000005499	2 retrocopies	retro_nleu_1079, retro_nleu_381,
Oryctolagus cuniculus	ENSOCUG00000005740	1 retrocopy	retro_ocun_1921,
Otolemur garnettii	ENSOGAG00000013202	2 retrocopies	retro_ogar_3502, retro_ogar_3504,
Pongo abelii	ENSPPYG00000007140	3 retrocopies	retro_pabe_1153, retro_pabe_2798, retro_pabe_777,
Pan troglodytes	ENSPTRG00000007824	3 retrocopies	retro_ptro_418, retro_ptro_622, retro_ptro_957 ,
Pteropus vampyrus	ENSPVAG00000002906	1 retrocopy	retro_pvam_1337,
Sarcophilus harrisii	ENSSHAG00000017346	1 retrocopy	retro_shar_691,
Ictidomys tridecemlineatus	ENSSTOG00000005816	1 retrocopy	retro_itri_1595,
Tupaia belangeri	ENSTBEG00000013916	3 retrocopies	retro_tbel_1609, retro_tbel_3046, retro_tbel_3772,
Tarsius syrichta	ENSTSYG00000011092	1 retrocopy	retro_tsyr_1528,
Tursiops truncatus	ENSTTRG00000005171	5 retrocopies	retro_ttru_1610, retro_ttru_1701, retro_ttru_519, retro_ttru_71, retro_ttru_929,