RetrogeneDB ID: retro_tsyr_92

Retrocopy location

• Organism: Tarsier (Tarsius syrichta)
• Coordinates: GeneScaffold_2672:190968..192094(+)
• Located in intron of: ENSTSYG00000010370

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ACTA2
• Ensembl ID: ENSTSYG00000008155
• Aliases: None
• Description: actin, alpha 2, smooth muscle, aorta [Source:HGNC Symbol;Acc:130]

Sequence

>retro_tsyr_92
ATGTGTGAAGAGGAGACCACTGCACTCATGTGTGACAATGGCTCTGGCCTGTGCATGGCAGGCTTTGCAGGAGATGATGC
CCCCCAGGCTGTCTTCCCTTCCATCGTGTGCCGCCCCCGCCACCAGGGTGTGATGGTGGGAATGGGCCAGAAGGACAGCT
ATGTGGGGGATGAGGTTCAGAGCAAGTGAGGAATCCTAACTCTCAAATACCCGATTGAGCACGGCATCATCACCAACTGG
GATGACATGGAGAAGATCTGGCACCACTCCTTCTACAATGAGCTGCGTGTAGCACCTGAAGAGCACCCCACCCTGCTCAC
GGAGGCCCCCTAAATCCCAAAGCCAACAGGGAGAAGATGACCCAGATCATGTTTGAAACCTTCAACGTCCCTGCCATGTA
TGTCGCCATTCAAGCTGTGCTCTCCCTCTATGCCTCTGGGCGCACTACAGGCATTGTCCTGGATTCAGGGGATGGTGTCA
CCCACAATGTCCTCATCTATGAGGGCTATGCCCTGCCCCATGCCATCATGCGCCTTGACCTGGCTGGCCGCGACCTCATG
GACTACCTCATGAAGATCCTCACAGAAGGAGGCTATTCCTTTGTGACCACAGCCGAGCAAGAAATCGTGCGAGACATCAA
GGAGAAACTATGCTATGTGGCCCTGGATTTTGAGAATGAGATGGCCACAGCAGCCTCCTCTTCCTCTCTGGAGAAGAGCT
ATGAGCTACCAGATGGGCAAGTCATCACCATTGGCAATGAGCGCTTCCGCTGCCTTGAGACCCTCTTCCAGCCTTCCTTC
ATTGGCATGGAGTCCACGGGAATTCATGAAGCAACCTACAATTCCATCATGAAGTGTGACATTGATATCCGTAAGGACTT
ATATGCCAACAATGTCCTCTCTGGGGGCACCACCATGTACCCTGGCATTGCTGACAGGATGCAGAAGGAGATCACAGCCC
TGGCCCCCAATGCCATGAAGATCAAGATTATTGCTCCCCCAGAGCGGAAGTACTCAGTGTGGATTGGGGGTTCTATCCTG
TCCTCTCTCTCCACCTTCCAGCAGATGTGGATCAGCAGCCTGAGTATGATGAAGCAGGGCCCTCCAGCGTCCACAGGAAG
TGCTTC

Alignment

ORF - retro_tsyr_92 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.67 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLK
          MCEEE..TAL.CDNGSGLC.AGFAGDDAP.AVFPSIV.RPRHQGVMVGMGQKDSYVGDE.QSK.GILTLK
Retrocopy MCEEE-TTALMCDNGSGLCMAGFAGDDAPQAVFPSIVCRPRHQGVMVGMGQKDSYVGDEVQSK*GILTLK

Parental  YPIEHGIITNWDDMEKIWHHSLYNELRVAPEEHPTLLTEA-PLNPKANREKMTQIMFETFNVPAMYVAIQ
          YPIEHGIITNWDDMEKIWHHS.YNELRVAPEEHPTLLTEA.PLNPKANREKMTQIMFETFNVPAMYVAIQ
Retrocopy YPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEA<PLNPKANREKMTQIMFETFNVPAMYVAIQ

Parental  AVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAERE
          AVLSLYASGRTTGIVLDSGDGVTHNV.IYEGYALPHAIMRLDLAGRDL.DYLMKILTE.GYSFVTTAE.E
Retrocopy AVLSLYASGRTTGIVLDSGDGVTHNVLIYEGYALPHAIMRLDLAGRDLMDYLMKILTEGGYSFVTTAEQE

Parental  IVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHET
          IVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRC.ETLFQPSFIGMES.GIHE.
Retrocopy IVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCLETLFQPSFIGMESTGIHEA

Parental  TYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILA
          TYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAP..MKIKIIAPPERKYSVWIGGSIL.
Retrocopy TYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPNAMKIKIIAPPERKYSVWIGGSILS

Parental  SLSTFQQMWIS-KQEYDEAGPSIVHRKCF
          SLSTFQQMWIS...EYDEAGPS.VHRKCF
Retrocopy SLSTFQQMWIS<QPEYDEAGPSSVHRKCF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Tarsius syrichta was not studied using RNA-Seq expression data.

ChIP-Seq

Tarsius syrichta was not studied using ChIP-Seq data.

EST

Tarsius syrichta was not studied using EST data.

TSS

Tarsius syrichta was not studied using FANTOM5 data.

Lab

retro_tsyr_92 was not experimentally validated.

Homology

Retrocopy orthology:

Tarsius syrichta does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000000759	3 retrocopies	retro_chof_1909, retro_chof_2042, retro_chof_21,
Dasypus novemcinctus	ENSDNOG00000006719	1 retrocopy	retro_dnov_32,
Echinops telfairi	ENSETEG00000008526	1 retrocopy	retro_etel_41,
Macropus eugenii	ENSMEUG00000010843	1 retrocopy	retro_meug_1374,
Myotis lucifugus	ENSMLUG00000015509	3 retrocopies	retro_mluc_190, retro_mluc_427, retro_mluc_90,
Nomascus leucogenys	ENSNLEG00000012233	1 retrocopy	retro_nleu_2313,
Oryctolagus cuniculus	ENSOCUG00000008193	3 retrocopies	retro_ocun_1306, retro_ocun_1421, retro_ocun_919,
Pongo abelii	ENSPPYG00000002459	1 retrocopy	retro_pabe_3027,
Sorex araneus	ENSSARG00000005778	1 retrocopy	retro_sara_732,
Tupaia belangeri	ENSTBEG00000017616	3 retrocopies	retro_tbel_1555, retro_tbel_3014, retro_tbel_4616,
Tarsius syrichta	ENSTSYG00000000406	1 retrocopy	retro_tsyr_2031,
Tarsius syrichta	ENSTSYG00000008155	5 retrocopies	retro_tsyr_1282, retro_tsyr_2102, retro_tsyr_858, retro_tsyr_9, retro_tsyr_92 ,
Vicugna pacos	ENSVPAG00000010621	3 retrocopies	retro_vpac_12, retro_vpac_355, retro_vpac_651,