mature_miRNA miRNA* pre-miRNA EST_contig mismatches bulges arm species source_database RFAM_best_hit RFAM_lowest_evalue miRBase_best_hit miRBase_lowest_evalue folding_energy secondary_structure TAGCTTATCAGACTGGTGTTGGC CGACAACAGTCTGAAGGCTGTC ATTGTCGTCTTTACATCTGTCACTCTCGGCCTGTCAAATAGCTTATCAGACTGGTGTTGGCTGTTAAGATTGCAAGGCGACAACAGTCTGAAGGCTGTCTGACATTTCGGGCTCTTTCATCT 2 1 5' arm Tetraodon_nigroviridis mirbase mir-21 9e-30 fru-mir-21 2e-33 -41.8 ........................(((((..(((((.(((((((.((((((((.(((((.((((.......)).)).))))).))))))))))))))).)))))..)))))........... (-41.80)