mature_miRNA miRNA* pre-miRNA EST_contig mismatches bulges arm species source_database RFAM_best_hit RFAM_lowest_evalue miRBase_best_hit miRBase_lowest_evalue folding_energy secondary_structure GAAGTTTGTTTTGTTTGTTTG ATCTAAACTAGTAAAGCTTTCT CTCATGTGGACAATCTAAACTAGTAAAGCTTTCTTTTATGGATGAATAACTGCTTGCAAGGAAGTTTGTTTTGTTTGTTTGTTGTGTTTG ATATCACAAGCAAAGAAAGTACAATTTATTTAAATTTTCCAAATTTTGATCTTAGTACACCTGATCAGGTGGCCGGTGATATGAAGGTACCACACCCACCCAAATTTTTCACAACATACCTATCAGCCTCGTCGATGTGCACTACTGATGTGCTGATTATTGAACTGAGGAAAAAAAAGCTAACAAAGAAGACTTTCTTCGACCCCCACCCCCTCGCCCCTCCTTCCACAGGGAAGACAGACATGGCATGCCGTCACCGTCGTCCCGGCTCACCTCGCCCAAACGCAGTCCAGGGGGCGGCGTGTCGAACCTGAGGGACACCATAGAGAACAAACTAGGGGTTTGTATCCCAGATTTTTCTTGTGGGTTGGTGTTTGGTTGTGCAATGAGATCTGGCTCATGTGGACAATCTAAACTAGTAAAGCTTTCTTTTATGGATGAATAACTGCTTGCAAGGAAGTTTGTTTTGTTTGTTTGTTGTGTTTGGTTGGTTGTTTTGTTTGGTTTGTTTTGTTGGTTGTTTGG 4 1 3' arm Aplysia_californica mirnest 100 100 -16.1 ........(((((..(((((.((..((((((((((....((...........))...))))))))))..)).))))).)))))....... (-16.1)