RetrogeneDB ID: retro_fcat_863

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: B3:117339230..117340100(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MSMO1
• Ensembl ID: ENSFCAG00000023004
• Aliases: None
• Description: methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:10545]

Sequence

>retro_fcat_863
GCAACAAATGGAAGTATCAGCATCTTTAGTTCAGCATCCTTGGCTGTGGAGTAGATAGAGTCACTTTTACCTGAGAACCC
TCTACAAGAACCATTTAAAATTGCTTGGAACTATATAGTGAGTAATTACACATAGTTCCAGATTGCAACATGGGAACCTT
GATAGTTCATGAGGCCCTTTATTTCTTGTTCTGTTTACCTGGATTTTTGTTTCAATTTATACCTTACATGAAAAAGTACA
AAATTCAGAAAAATAAATCAGAAACATGGGAAAGCCAATAGAAATGTTTTAAAGTACTTCTCTTTAATCAGTTTTGTATC
CAGCTTCCTTTGATTTGTGGAACTTATTATTTTACAGAGTATTTTAATATTCCTTATGATTGGGAAAGAATGCCAAGATG
GTATATGCTGTTGGGAAGATGCGTAGGCTGTGCGGTGATTGAGGACGCTTGGCACCATTTTCTGCATAGGCTCTTACATC
ACAGAAGAATACATAAAATATATTCATAAAATTCATCATGAATTTCAGGCGCCATTTGGGATGGAAGCTGACTATGCATA
TCCGTTGGAAACTCTGATTTTCGGAACTGGATTTTCCATTGGAATCATGCTTCTGGGTGATCATGTCATTCTTCTTTGGG
CATGGGTGACCATTCGTTCGATAGACACTATTGATGTCCATAGTGGTGGTGACATTCCTCTCAACCCTTTAAATCTGATC
CCTTTCATTGCTGGTTCTCAACATCATGATTTCCACCACATGAACTTCATTGGAAATTACGCTTCAGCATTTACATGGTG
GGATAGAATTTTTGGAAGAGACTCTCAGTTTATTGCCTACAATGAAAAGGTGAAGAAGGTTGCAAAAAAA

Alignment

ORF - retro_fcat_863 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 84.93 %
• Parental protein coverage: 98.98 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  ATNESISIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATW-GSLIVHEALYFLFCLPGF
          ATN.SISIFSSASLAVE...SLLPENPLQEPFK.AWNY...NYT.FQIATW.G.LIVHEALYFLFCLPGF
Retrocopy ATNGSISIFSSASLAVE*IESLLPENPLQEPFKIAWNYIVSNYT*FQIATW<GTLIVHEALYFLFCLPGF

Parental  LFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWCLLLV
          LFQFIPYMKKYKIQK.K.ETWE.Q.KCFKVLLFN.FCIQLPLICGTYYFTEYFNIPYDWERMPRW..LL.
Retrocopy LFQFIPYMKKYKIQKNKSETWESQ*KCFKVLLFNQFCIQLPLICGTYYFTEYFNIPYDWERMPRWYMLLG

Parental  KCLGCAVIEDTWHYFLHRLLHHKRIYK-YIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIMLLCDH
          .C.GCAVIED.WH.FLHRLLHH.RI.K.YIHK.HHEFQAPFGMEA.YA.PLETLI.GTGF.IGIMLL.DH
Retrocopy RCVGCAVIEDAWHHFLHRLLHHRRIHK>YIHKIHHEFQAPFGMEADYAYPLETLIFGTGFSIGIMLLGDH

Parental  VIFLWAWVTIRLMETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQFI
          VI.LWAWVTIR...TIDVHSG.DIPLNPLNLIPF.AGS.HHDFHHMNFIGNYAS.FTWWDRIFG.DSQFI
Retrocopy VILLWAWVTIRSIDTIDVHSGGDIPLNPLNLIPFIAGSQHHDFHHMNFIGNYASAFTWWDRIFGRDSQFI

Parental  AYNEKMKKFGKK
          AYNEK.KK..KK
Retrocopy AYNEKVKKVAKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	1.03 RPM	67.14 RPM
SRP017611_kidney	0.10 RPM	33.80 RPM
SRP017611_liver	0.20 RPM	184.59 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_863 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_863 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005596	1 retrocopy	retro_amel_447,
Choloepus hoffmanni	ENSCHOG00000007550	2 retrocopies	retro_chof_1657, retro_chof_560,
Callithrix jacchus	ENSCJAG00000009301	1 retrocopy	retro_cjac_2245,
Felis catus	ENSFCAG00000023004	1 retrocopy	retro_fcat_863 ,
Homo sapiens	ENSG00000052802	1 retrocopy	retro_hsap_4672,
Gorilla gorilla	ENSGGOG00000015730	1 retrocopy	retro_ggor_2898,
Loxodonta africana	ENSLAFG00000007061	1 retrocopy	retro_lafr_570,
Macaca mulatta	ENSMMUG00000012994	1 retrocopy	retro_mmul_2486,
Nomascus leucogenys	ENSNLEG00000006501	1 retrocopy	retro_nleu_2164,
Oryctolagus cuniculus	ENSOCUG00000003769	1 retrocopy	retro_ocun_1454,
Otolemur garnettii	ENSOGAG00000009281	2 retrocopies	retro_ogar_182, retro_ogar_3404,
Pan troglodytes	ENSPTRG00000016574	1 retrocopy	retro_ptro_3104,
Pteropus vampyrus	ENSPVAG00000013707	4 retrocopies	retro_pvam_1405, retro_pvam_550, retro_pvam_598, retro_pvam_784,
Sorex araneus	ENSSARG00000013546	1 retrocopy	retro_sara_635,
Sarcophilus harrisii	ENSSHAG00000000135	1 retrocopy	retro_shar_530,
Tursiops truncatus	ENSTTRG00000012897	2 retrocopies	retro_ttru_20, retro_ttru_801,