RetrogeneDB ID: retro_ggor_1376

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 18:33586691..33587287(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENSG00000141580
• Ensembl ID: ENSGGOG00000006132
• Aliases: None
• Description: None

Sequence

>retro_ggor_1376
GTCCTCTGTCCCAATAGCAGCAACTCTTTTCTGGCCTTGCCAGGCATGCACACGGGCCATGTTCAGCTCGTGGACTGGGC
CAGCACAGAGAAGCCACCTGTGGACATTCCCACTCCTGAGGGCATCCTGAGCTGCATCATACTCAACCTGCAGGGAACAA
GAATTGCAACCACACTCGCAAAAGGGACCCTTATAAGAATATTTGATACCTCATCAGGACATTTAATCCAGGAACTATGA
AGAGGATCTCAAGCAGCTAATGTTTTCTGCATTAACTTCAATCAAGATGAGTCCTTCATCTGCATATCCAGTGACCACAG
CACAGTGCACATTTTTGCAGCTGAAGACCCAGGAAGGAATAAACAGTCCAATTTGGTGTCAGCTAGTTTCCTTCCAAAAT
CCTTTAGTTGCAAACGGGTTTCTCCAAGTTTCAGGTTCCCTTGGGCTCTCCATGCATTTGTGCCCTTGGAACAGAGCCAA
ATGCGGTCACTGCGATTTGTGCAGATGTCGGCTACTACAAATTCCTATTCAACCCCAGAAGGGAATGCATCCCAGACATC
TATGCGCAGTTTCTAGAAATGATCTACGACAAGCTG

Alignment

ORF - retro_ggor_1376 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81. %
• Parental protein coverage: 71.84 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  VLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDT
          VLCPNS.NS.LA.PG.HTGHVQLVD.ASTEKPPVDIP..EG.LSCI.LNLQGTRIAT...KGTLIRIFDT
Retrocopy VLCPNSSNSFLALPGMHTGHVQLVDWASTEKPPVDIPTPEGILSCIILNLQGTRIATTLAKGTLIRIFDT

Parental  SSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSK-W
          SSGHLIQEL.RGSQAAN..CINFNQD.S.IC.SSDH.TVHIFAAEDP.RNKQS.L.SASFLPK.FS.K..
Retrocopy SSGHLIQEL*RGSQAANVFCINFNQDESFICISSDHSTVHIFAAEDPGRNKQSNLVSASFLPKSFSCK<T

Parental  SFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
          .FSKFQVP.GSPCICA.GTEPNAV.AICAD..YYKFLFNP..ECI.D.YAQFLEM..DKL
Retrocopy GFSKFQVPLGSPCICALGTEPNAVTAICADVGYYKFLFNPRRECIPDIYAQFLEMIYDKL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	12.42 RPM
SRP007412_cerebellum	0.00 RPM	13.12 RPM
SRP007412_heart	0.03 RPM	2.31 RPM
SRP007412_kidney	0.04 RPM	9.98 RPM
SRP007412_liver	0.00 RPM	5.43 RPM
SRP007412_testis	0.00 RPM	17.72 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1376 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1376 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1879
Pongo abelii	retro_pabe_1559
Macaca mulatta	retro_mmul_1330

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 16 retrocopies.

Species	Parental gene accession	Retrocopies number
Cavia porcellus	ENSCPOG00000005657	1 retrocopy	retro_cpor_322,
Homo sapiens	ENSG00000141580	2 retrocopies	retro_hsap_1820, retro_hsap_1879,
Gorilla gorilla	ENSGGOG00000000589	1 retrocopy	retro_ggor_2075,
Gorilla gorilla	ENSGGOG00000006132	2 retrocopies	retro_ggor_1376 , retro_ggor_2173,
Macropus eugenii	ENSMEUG00000013344	1 retrocopy	retro_meug_233,
Macaca mulatta	ENSMMUG00000021803	1 retrocopy	retro_mmul_1330,
Mus musculus	ENSMUSG00000025173	1 retrocopy	retro_mmus_1487,
Nomascus leucogenys	ENSNLEG00000010516	1 retrocopy	retro_nleu_1227,
Pongo abelii	ENSPPYG00000008785	2 retrocopies	retro_pabe_150, retro_pabe_1559,
Pan troglodytes	ENSPTRG00000009807	3 retrocopies	retro_ptro_1171, retro_ptro_1262, retro_ptro_2912,
Pteropus vampyrus	ENSPVAG00000006212	1 retrocopy	retro_pvam_158,