RetrogeneDB ID: retro_ggor_1961

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:100438755..100439357(-)
• Located in intron of: ENSGGOG00000009993

Retrocopy information

• Ensembl ID: ENSGGOG00000025191
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: BTF3
• Ensembl ID: ENSGGOG00000000166
• Aliases: None
• Description: None

Sequence

>retro_ggor_1961
CCTTTAGCTGCCGTCTTGCATCTCCACATGTGTGTGCCTAATCTCAGCTGGTCCACCCGGGACCCTCTGAGCACCAACCC
TAGTTCTCTGCATGGCCCCTTATCTGCTCTGATAGGATGAAAGAAACAATCATGAATCAGAAAAAACTTGTCAAACTGCA
GGCACAAGTGTGCATTGGTGGGAAAGGAACTGTTCGTAGAAGGAAGAAGGTGGTTCATAGAACAGCCACAGCAGATGATA
AAAAACTTCACTTCTCCTTAAAGAAGTTAGGGGTAAACAATATCTTTGGTATTGAAGAGGTGCATATGTTTACAAACCAA
GGAACAGTGATCCACTTTAACAACCCTAAAGTTCAGGCATCTCTGGGAGCAAACACTTTCACCATTACAGGCCATGCCGA
GACAAAGCAGCTGACAGAAATGCTACCCAACATCTTAAACCAGCTTGGTGTAGACAGTCTGAACAGTTTAAGCAGACTGG
CTGAAGCTTTGCCCAAACAATCCGTGGATGGAAAAGCACCACTTGCTACTGGGGAGGATGATGATGATGAAGTTCCTGAT
CTTGTGGAGAATTTTGATGAGGCTTCCAAGAATGAGGCAAAC

Alignment

ORF - retro_ggor_1961 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.63 %
• Parental protein coverage: 95.71 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  PLAAILRPRVCAPNLRWSTRDPLSTNPSPPRGPLFA-PTRMKETIMNQEKLAKLQAQVRIGGKGTARRKK
          PLAA.L....C.PNL.WSTRDPLSTNPS...GPL.A...RMKETIMNQ.KL.KLQAQV.IGGKGT.RR.K
Retrocopy PLAAVLHLHMCVPNLSWSTRDPLSTNPSSLHGPLSA<SDRMKETIMNQKKLVKLQAQVCIGGKGTVRRRK

Parental  KVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLT
          KVVHRTATADDKKL.FSLKKLGVNNI.GIEEV.MFTNQGTVIHFNNPKVQASL.ANTFTITGHAETKQLT
Retrocopy KVVHRTATADDKKLHFSLKKLGVNNIFGIEEVHMFTNQGTVIHFNNPKVQASLGANTFTITGHAETKQLT

Parental  EMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN
          EMLP.ILNQLG.DSL.SL.RLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN
Retrocopy EMLPNILNQLGVDSLNSLSRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	60.76 RPM
SRP007412_cerebellum	0.12 RPM	67.41 RPM
SRP007412_heart	0.03 RPM	37.71 RPM
SRP007412_kidney	0.04 RPM	133.91 RPM
SRP007412_liver	0.03 RPM	95.94 RPM
SRP007412_testis	0.10 RPM	119.04 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1961 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1961 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2819
Pan troglodytes	retro_ptro_1912
Pongo abelii	retro_pabe_2207

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 70 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000010012	5 retrocopies	retro_btau_1161, retro_btau_1344, retro_btau_1361, retro_btau_459, retro_btau_551,
Callithrix jacchus	ENSCJAG00000016600	4 retrocopies	retro_cjac_1454, retro_cjac_1673, retro_cjac_2640, retro_cjac_281,
Ciona savignyi	ENSCSAVG00000009653	1 retrocopy	retro_csav_25,
Equus caballus	ENSECAG00000021629	1 retrocopy	retro_ecab_200,
Echinops telfairi	ENSETEG00000017341	5 retrocopies	retro_etel_1216, retro_etel_1394, retro_etel_1997, retro_etel_405, retro_etel_960,
Gorilla gorilla	ENSGGOG00000000166	10 retrocopies	retro_ggor_1082, retro_ggor_1682, retro_ggor_1961 , retro_ggor_2054, retro_ggor_2399, retro_ggor_2647, retro_ggor_2667, retro_ggor_548, retro_ggor_81, retro_ggor_946,
Microcebus murinus	ENSMICG00000017182	3 retrocopies	retro_mmur_1219, retro_mmur_1301, retro_mmur_651,
Monodelphis domestica	ENSMODG00000001762	3 retrocopies	retro_mdom_189, retro_mdom_454, retro_mdom_931,
Nomascus leucogenys	ENSNLEG00000004718	9 retrocopies	retro_nleu_1081, retro_nleu_1199, retro_nleu_1284, retro_nleu_1446, retro_nleu_1797, retro_nleu_2526, retro_nleu_451, retro_nleu_496, retro_nleu_734,
Oryctolagus cuniculus	ENSOCUG00000024914	6 retrocopies	retro_ocun_1186, retro_ocun_1299, retro_ocun_1364, retro_ocun_446, retro_ocun_857, retro_ocun_916,
Pongo abelii	ENSPPYG00000029576	14 retrocopies	retro_pabe_1154, retro_pabe_1477, retro_pabe_180, retro_pabe_1885, retro_pabe_1956, retro_pabe_2207, retro_pabe_2458, retro_pabe_2918, retro_pabe_2919, retro_pabe_2932, retro_pabe_3329, retro_pabe_3484, retro_pabe_558, retro_pabe_649,
Rattus norvegicus	ENSRNOG00000016912	9 retrocopies	retro_rnor_187, retro_rnor_194, retro_rnor_2121, retro_rnor_2520, retro_rnor_2990, retro_rnor_2991, retro_rnor_2999, retro_rnor_836, retro_rnor_953,