RetrogeneDB ID: retro_mdom_258

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 4:266233211..266234270(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMODG00000024309
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSMODG00000017334
• Aliases: None
• Description: Ribose-phosphate pyrophosphokinase [Source:UniProtKB/TrEMBL;Acc:F6WVR9]

Sequence

>retro_mdom_258
ATGATGGAGAGGCCATCAGCAGCAGATGCCGCCACCACCACCATCACCGTCACCCCTGCCACCACCACAGCCACTGATGC
AGTCTTCCACCTAATGCCCGCCATGCCCAACATCCTGCTGTTCAGTGGCAACTCGCACCAGGACCTGTCCCAGAAAGTGG
CAGACAGGTTGGGGCTGAAACTGGGCAAAGTGGTCTCTACGAAATTCAGCAATCAGGAGACCAGTGTAGAAATCGGTGAA
AGTGTGAGAGGGGAAGATGTCTACATCATCCAAAGCGGCTGTGGGGAAATTAATGATAACTTGATGGAACTTCTCCTTAT
GATCAATGCTTGCAAAATTGCATCATCATCCAGGGTGACTGCAGTAATCCCATGTTTTCCATATGCCCGACAAGATAAAA
AAGACAAGAGTCGTGTTCCAATTTCTGCAAAACTTGTGGCCAATATGCTTTCAGTGGCTGGGGCTGATCATATCATTACA
ATGGATCTCCATGCTTCTCAGATACAAGGATTTTTTGATATTCCAGTGGATAATATGTATGCAGAACCTGCATTCTTACA
ATGGATTCAAAAAAATATTACAGAATGGAGGAATTGTATCATTGTGTCCCCAGATGCTGGTGGAGCTAAAAGAGTGACGT
CAATTGCTGACAGGTTGAATGTGGAGTTTGCTTTGATTCATAAAGAAAGAAAGAAGGCAAATGAGGTAGACAGGATGGTT
TTGGTTGGCGATGTGAAGAATCGTGTAGCCATTCTTGTGGATGACATAGCTGATACATGTGGCACAATATGCCATGCTGC
GGATAAGTTACTGTCTGCTGGAGCCACCAAAATTTATGCTATTGTAACTCATGGAATCTTTTCTGGACCAGCTATTTCCA
GAATTAATAATGCAGCATTTGAGGCTGTGGTGGTCACAAATACAATTCCACAAGAGGACAAAATGGATCGCTGCTCTAAA
ATCCAGGTTATTGACATTTCAATGATACTGGCTGAAACAATACGGAGAACACACAATGGTGAATCTGTGTCTTACCTGTT
CAGTCAAGTTCCACTATAA

Alignment

ORF - retro_mdom_258 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.71 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MPNIVLFSGSSHQDLSQKVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMEL
          MPNI.LFSG.SHQDLSQKVADRLGL.LGKVV..KFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMEL
Retrocopy MPNILLFSGNSHQDLSQKVADRLGLKLGKVVSTKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMEL

Parental  LIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDI
          L.MINACKIASSSRVTAVIPCFPYARQDKKDKSR.PISAKLVANMLSVAGADHIITMDLHASQIQGFFDI
Retrocopy LLMINACKIASSSRVTAVIPCFPYARQDKKDKSRVPISAKLVANMLSVAGADHIITMDLHASQIQGFFDI

Parental  PVDNLYAEPAVLQWIRENIAEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGD
          PVDN.YAEPA.LQWI..NI.EWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGD
Retrocopy PVDNMYAEPAFLQWIQKNITEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGD

Parental  VKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDK
          VK.RVAILVDD.ADTCGTICHAADKLLSAGATK.YAI.THGIFSGPAISRINNAAFEAVVVTNTIPQEDK
Retrocopy VKNRVAILVDDIADTCGTICHAADKLLSAGATKIYAIVTHGIFSGPAISRINNAAFEAVVVTNTIPQEDK

Parental  MKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
          M..CSKIQVIDISMILAE.IRRTHNGESVSYLFS.VPL
Retrocopy MDRCSKIQVIDISMILAETIRRTHNGESVSYLFSQVPL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_258 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_258 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000011662	2 retrocopies	retro_cfam_1037, retro_cfam_1433,
Callithrix jacchus	ENSCJAG00000003885	1 retrocopy	retro_cjac_364,
Cavia porcellus	ENSCPOG00000007206	1 retrocopy	retro_cpor_16,
Dipodomys ordii	ENSDORG00000007577	2 retrocopies	retro_dord_223, retro_dord_605,
Echinops telfairi	ENSETEG00000005166	2 retrocopies	retro_etel_1613, retro_etel_669,
Felis catus	ENSFCAG00000026323	1 retrocopy	retro_fcat_527,
Monodelphis domestica	ENSMODG00000009171	1 retrocopy	retro_mdom_1440,
Monodelphis domestica	ENSMODG00000017334	4 retrocopies	retro_mdom_1323, retro_mdom_1359, retro_mdom_258 , retro_mdom_834,
Otolemur garnettii	ENSOGAG00000016087	1 retrocopy	retro_ogar_1440,
Procavia capensis	ENSPCAG00000001197	2 retrocopies	retro_pcap_219, retro_pcap_292,
Pongo abelii	ENSPPYG00000020125	1 retrocopy	retro_pabe_3431,
Pteropus vampyrus	ENSPVAG00000009452	1 retrocopy	retro_pvam_1224,
Sorex araneus	ENSSARG00000007710	1 retrocopy	retro_sara_18,
Ictidomys tridecemlineatus	ENSSTOG00000006056	1 retrocopy	retro_itri_1668,
Tupaia belangeri	ENSTBEG00000009917	1 retrocopy	retro_tbel_1245,
Tursiops truncatus	ENSTTRG00000003226	1 retrocopy	retro_ttru_1494,