RetrogeneDB ID: retro_mmul_21

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 5:50256875..50257565(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000021988
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: NAA10
• Ensembl ID: ENSMMUG00000000322
• Aliases: None
• Description: None

Sequence

>retro_mmul_21
ATGAACATCCGCAACGCTCGGCCAGACGACCTGATGAATATGCAGCACTGCAACCTCCTTTGCCTTCCTGAGAACTACCA
GATGAAATACTATTTATATCATGGCCTTTCCTGGCCCCAGCTTTCTTACATCGCTGAGGATGAGGACGGGAAGATTGTGG
GCTATGTCCTAGCCAAAATGGAGGAGGACCCAGATGATGTCCCGCATGGCCATATCACCTCACTTGCCGTGAAGCGTTCA
CACCGGCGCCTCGGCCTGGCCCAGAAGCTGATGGACCAGGCCTCTAGGGCCATGATAGAGAACTTTAACGCCAAATACGT
GTCTCTGCATGTCAGGAAGAGTAACCGGGCAGCCTTGCACCTCTATTCTAACACCCTCAACTTTCAGATTAGTGAGGTGG
AACCTAAATACTATGCAGATGGGGAAGATGCTTATGCTATGAAGCGGGATCTCTCGCAGATGGCAGATGAGCTGAGACGA
CAAGTGGACCTGAAGAAGGGCGGGTATGTGGTCCTGGGCTCCAGGGAGAACCAGGAGACCCAGGGCAGCACACTTTGTGG
TTCTGAAGAGGCCTGTCAGCAAAAGAACCCGGATACCGAAGAAAGTGGCAGTGACAGCAAAGAACCTAAGGAGTCTGTGG
AGAGCACCAACGTCCAAGACAGCTCAGAAGGCTCGGATTCCACCTCCTAG

Alignment

ORF - retro_mmul_21 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.13 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHG
          MNIRNARP.DLMNMQHCNLLCLPENYQMKYY.YHGLSWPQLSYIAEDE.GKIVGYVLAKMEEDPDDVPHG
Retrocopy MNIRNARPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEDPDDVPHG

Parental  HITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYAD
          HITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYAD
Retrocopy HITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYAD

Parental  GEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSK
          GEDAYAMKRDL.QMADELRR...LK.KG..VVLG..EN..E..G.....S.EAC...K....E.SG.DSK
Retrocopy GEDAYAMKRDLSQMADELRRQVDLK-KGGYVVLGSRENQ-ETQGSTLCGSEEAC-QQKNPDTEESGSDSK

Parental  DLSEVSETTESTDVKDSSEASDSAS
          ...E..E..EST.V.DSSE.SDS.S
Retrocopy ---EPKESVESTNVQDSSEGSDSTS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	27.12 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	51.09 RPM
SRP007412_cerebellum	0.00 RPM	29.06 RPM
SRP007412_heart	0.00 RPM	33.27 RPM
SRP007412_kidney	0.00 RPM	35.45 RPM
SRP007412_liver	0.00 RPM	49.52 RPM
SRP007412_testis	46.55 RPM	4.11 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_21 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_21 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_21 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Bos taurus	retro_btau_177
Callithrix jacchus	retro_cjac_132

---

Parental genes homology:

Parental genes homology involve 22 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000018457	1 retrocopy	retro_amel_162,
Bos taurus	ENSBTAG00000047702	1 retrocopy	retro_btau_177,
Canis familiaris	ENSCAFG00000019415	1 retrocopy	retro_cfam_167,
Callithrix jacchus	ENSCJAG00000014506	1 retrocopy	retro_cjac_132,
Equus caballus	ENSECAG00000015203	1 retrocopy	retro_ecab_717,
Felis catus	ENSFCAG00000028705	1 retrocopy	retro_fcat_51,
Homo sapiens	ENSG00000102030	1 retrocopy	retro_hsap_13,
Gorilla gorilla	ENSGGOG00000009788	1 retrocopy	retro_ggor_196,
Macropus eugenii	ENSMEUG00000006054	2 retrocopies	retro_meug_1787, retro_meug_554,
Myotis lucifugus	ENSMLUG00000014267	1 retrocopy	retro_mluc_152,
Macaca mulatta	ENSMMUG00000000322	1 retrocopy	retro_mmul_21 ,
Mustela putorius furo	ENSMPUG00000008989	1 retrocopy	retro_mputfur_1424,
Mus musculus	ENSMUSG00000031388	1 retrocopy	retro_mmus_1416,
Nomascus leucogenys	ENSNLEG00000013724	1 retrocopy	retro_nleu_57,
Otolemur garnettii	ENSOGAG00000013263	1 retrocopy	retro_ogar_260,
Pongo abelii	ENSPPYG00000020861	1 retrocopy	retro_pabe_2530,
Pan troglodytes	ENSPTRG00000022419	1 retrocopy	retro_ptro_23,
Pteropus vampyrus	ENSPVAG00000000463	1 retrocopy	retro_pvam_1225,
Sarcophilus harrisii	ENSSHAG00000005952	1 retrocopy	retro_shar_362,
Sus scrofa	ENSSSCG00000012791	1 retrocopy	retro_sscr_987,
Ictidomys tridecemlineatus	ENSSTOG00000010237	1 retrocopy	retro_itri_1435,
Tursiops truncatus	ENSTTRG00000007455	1 retrocopy	retro_ttru_198,