RetrogeneDB ID: retro_nleu_429

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397265.1:2785648..2786936(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PSMC1
• Ensembl ID: ENSNLEG00000017013
• Aliases: None
• Description: None

Sequence

>retro_nleu_429
ATGGGTCAAAGTTAGAGTGGTGGTTATGGTCCTAGAGGTGGCAAGAAGGATGACAAGGACAAGAAAAAGAAATATGAACC
TCTTGTACCAATTAGAGTGGGGGAAAAGAAGAAGAAAACAAAGAGACCAGATGCTGCCAGCAAACTGCCACTGGTGATAC
CTCACACTCAATGCCAATTAAAATTACTGAAATTAGTGAGAATGAAAGACTCTATTCTCATGGAGGAAGAAGCCATTAGA
AATCAGGAACAGATAAAACCATTAGAAGAAAAGCATTAGGAGGGAAAAGCAAAAGTGGATGACCTGAGGGGGACCACTAT
GATACTAGACACCTTGGAAGAGATCATTGATGGCAGTCACACCATCATGTCTAGATATGTGGGGTCAGAACACTACATCA
GCTTTCTTTTATTTGTAGACAAGGATCTGCTGGAACTGGCTTCTTGGTCCTGCTCAACTGCAAGTTGAATACCATGATAA
GGGTGCTGATGAATGACACAGATTTCCTAGTCACAGTGATGAAAGTGGAAATGGTACCCAGGAGACCTATGCCAGTATTG
GTGGTTGGACAACCAAATCCAGGAAATTAAGTAAGAAATCTGTGGAGCTTCCTCTCACTCATCCTGAATATTATGAAGAG
ATGGGTTTAAAGCCAGATAAGGCGGTCATTCTCTGTGGTCCATATGCCACAGGTAAAACCTTGTTAGCCAAAGCAATAGC
ATGTCAAACCTCAGCCACTTTCTTGAGGGTGGTTGGTTCTGAACTTATTCAGAAGTACCTTGGTGATGGGCCGAAACTCA
CATGGGAATTGTTTTGAGCTGCTGAAGAATATACACCTTTCATCATGTTTATTGATGAAATTGATGCCATTGGGAAAAAC
TATGATTCAAATTTTGGTGGTGAGAGAGAAATTTAGTGAACAGTGTTGGAACTGTTGAACCAGTTGTACGGATCTTATTC
AAGGGGAGATATTAAAGTTATCATAGCCACAAACCAAATAGAAACTTAGGATCCAACACTTACCAGGCCAGGCTACATTG
ACAGGAAGACTGAGTTCCCCCTGCCTGATAAAAGGATGAAGAAGTACATTTTTCAGATTCACATGAACAATATGACTTTG
GCCAGTGATGTAACCCTGGACAACTTGATTAAGGCTAAAGATGACTGCTCTGGTGCTGACATCCGGGCAGTCTGTACAGA
AGGTGATCTGATGACCTTAAGAGAAAGTAGAATGAAAGTAACAAATAAACACTTCAAAAAATCATAAGAAAATATTCTTT
GTGAAAAA

Alignment

ORF - retro_nleu_429 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.44 %
• Parental protein coverage: 97.73 %
• Number of stop codons detected: 7
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKD
          MGQS.SGG.GP.GGKKDDKDKKKKYEP.VP.RVG.KKKKTK.PDAASKLPLV.PHTQC.LKLLKL.R.KD
Retrocopy MGQS*SGGYGPRGGKKDDKDKKKKYEPLVPIRVGEKKKKTKRPDAASKLPLVIPHTQCQLKLLKLVRMKD

Parental  YLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVD
          ..LMEEE.IRNQEQ.KPLEEK..E...KVDDLRGT.M...TLEEIID..H.I.S..VGSEHY.S.L.FVD
Retrocopy SILMEEEAIRNQEQIKPLEEKH*EGKAKVDDLRGTTMILDTLEEIIDGSHTIMSRYVGSEHYISFLLFVD

Parental  KDLLE-PGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAP-QETYADIGGLDNQIQEI-KESVELPLTH
          KDLLE..G..VLLN.K....I.VLM.DTD.LVTVMKVE..P.QETYA.IGG.........K.SVELPLTH
Retrocopy KDLLE<TGFLVLLNCKLNTMIRVLMNDTDFLVTVMKVEMVP<QETYASIGGWTTKSRKLSKKSVELPLTH

Parental  PEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEH
          PEYYEEMG.KP.K.VIL.GP..TGKTLLAKA.A.QTSATFLRVVGSELIQKYLGDGPKL..ELF..AEE.
Retrocopy PEYYEEMGLKPDKAVILCGPYATGKTLLAKAIACQTSATFLRVVGSELIQKYLGDGPKLTWELF*AAEEY

Parental  APSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRI
          .P.I.FIDEIDAIG.K.YDSN.GGEREI..T.LELLNQL.G..SRGD.KVI.ATN.IET.DP.L.RPG.I
Retrocopy TPFIMFIDEIDAIG-KNYDSNFGGEREI**TVLELLNQLYGSYSRGDIKVIIATNQIET*DPTLTRPGYI

Parental  DRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE
          DRK.EFPLPD...KK.IFQIH...MTLA.DVTLD.LI.AKDD.SGADI.A.CTE..LM.LRE.RMKVTN.
Retrocopy DRKTEFPLPDKRMKKYIFQIHMNNMTLASDVTLDNLIKAKDDCSGADIRAVCTEGDLMTLRESRMKVTNK

Parental  DFKKSKENVLYKK
          .FKKS.EN.L..K
Retrocopy HFKKS*ENILCEK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_429 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 72 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000017510	2 retrocopies	retro_cfam_1238, retro_cfam_1562,
Choloepus hoffmanni	ENSCHOG00000013595	1 retrocopy	retro_chof_1954,
Callithrix jacchus	ENSCJAG00000017701	7 retrocopies	retro_cjac_1152, retro_cjac_1537, retro_cjac_2417, retro_cjac_2433, retro_cjac_4219, retro_cjac_661, retro_cjac_678,
Dasypus novemcinctus	ENSDNOG00000006458	1 retrocopy	retro_dnov_2162,
Homo sapiens	ENSG00000100764	10 retrocopies	retro_hsap_1090, retro_hsap_1278, retro_hsap_2080, retro_hsap_2658, retro_hsap_2810, retro_hsap_2873, retro_hsap_3323, retro_hsap_3416, retro_hsap_3793, retro_hsap_975,
Gorilla gorilla	ENSGGOG00000010620	8 retrocopies	retro_ggor_1004, retro_ggor_1298, retro_ggor_1629, retro_ggor_1954, retro_ggor_1993, retro_ggor_2309, retro_ggor_780, retro_ggor_858,
Macropus eugenii	ENSMEUG00000001526	1 retrocopy	retro_meug_623,
Microcebus murinus	ENSMICG00000016733	7 retrocopies	retro_mmur_1039, retro_mmur_1063, retro_mmur_1245, retro_mmur_1577, retro_mmur_216, retro_mmur_839, retro_mmur_983,
Macaca mulatta	ENSMMUG00000022990	1 retrocopy	retro_mmul_255,
Nomascus leucogenys	ENSNLEG00000017013	10 retrocopies	retro_nleu_1123, retro_nleu_1163, retro_nleu_1589, retro_nleu_1625, retro_nleu_1669, retro_nleu_2318, retro_nleu_2625, retro_nleu_429 , retro_nleu_616, retro_nleu_706,
Oryctolagus cuniculus	ENSOCUG00000006231	4 retrocopies	retro_ocun_1135, retro_ocun_1212, retro_ocun_1654, retro_ocun_411,
Otolemur garnettii	ENSOGAG00000032343	2 retrocopies	retro_ogar_3014, retro_ogar_367,
Pongo abelii	ENSPPYG00000025948	9 retrocopies	retro_pabe_1059, retro_pabe_153, retro_pabe_2379, retro_pabe_2408, retro_pabe_2737, retro_pabe_2832, retro_pabe_3099, retro_pabe_825, retro_pabe_907,
Pan troglodytes	ENSPTRG00000006623	9 retrocopies	retro_ptro_1530, retro_ptro_1904, retro_ptro_1944, retro_ptro_2153, retro_ptro_2321, retro_ptro_2573, retro_ptro_672, retro_ptro_742, retro_ptro_874,