RetrogeneDB ID: retro_rnor_2369

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 6:65322266..65322736(-)
• Located in intron of: ENSRNOG00000025049

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Max
• Ensembl ID: ENSRNOG00000008049
• Aliases: None
• Description: Protein max [Source:UniProtKB/Swiss-Prot;Acc:P52164]

Sequence

>retro_rnor_2369
AGCGAGAGAATTGAGGTGAAGAGCAAAGAAGAGCAACTGAGGTTTCAATCTGCGGCTGACAAACGGGCTCACCATCATGC
ACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGA
AGGCATCCTAGGCCCAAATCCTAGACAAAGCAACAGAGTACATCCAGTATATGTGAAGGAAAAACCATAGGCACCAGCAA
GACATTGATGACCTCAAGCGGCAGAATGCTGTTCTGGAGCAACAAGTCGGTGCACTGGAGAAGGCAAGATCAAGTGCACA
ACTGCAGACCAACTACCCCTCCTCAGACAACAGCCTCTACACCAAGGCCAAGGGCGGCACTATCTCTGCCTTTGATGGGG
TTCAGACTCCAGCTCAGAGTCCAAGCCTGAGGAGCCCCAGAACAGGAAGAAACTGCGGATGGAGGCCAGC

Alignment

ORF - retro_rnor_2369 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.51 %
• Parental protein coverage: 98.12 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  NDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQY
          ...IEV.S.EEQ.RFQSAADKRAHH.ALERKRRDHIKDSFHSLRDSVPSLQGEKAS.AQILDKATEYIQY
Retrocopy SERIEVKSKEEQLRFQSAADKRAHHHALERKRRDHIKDSFHSLRDSVPSLQGEKAS*AQILDKATEYIQY

Parental  MRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDG-GSDSSS
          M.RKNH.HQQDIDDLKRQNA.LEQQV.ALEKARSSAQLQTNYPSSDNSLYT.AKGGTISAFDG.GSDSSS
Retrocopy M*RKNHRHQQDIDDLKRQNAVLEQQVGALEKARSSAQLQTNYPSSDNSLYTKAKGGTISAFDG<GSDSSS

Parental  ESEPEEPQNRKKLRMEAS
          ES.PEEPQNRKKLRMEAS
Retrocopy ESKPEEPQNRKKLRMEAS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	36.16 RPM
SRP017611_kidney	0.07 RPM	29.94 RPM
SRP017611_liver	0.00 RPM	17.82 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_2369 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_2369 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_2369 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003472	2 retrocopies	retro_amel_1261, retro_amel_1606,
Canis familiaris	ENSCAFG00000016212	2 retrocopies	retro_cfam_1179, retro_cfam_1325,
Callithrix jacchus	ENSCJAG00000019702	2 retrocopies	retro_cjac_2057, retro_cjac_2556,
Cavia porcellus	ENSCPOG00000010172	1 retrocopy	retro_cpor_710,
Erinaceus europaeus	ENSEEUG00000003973	3 retrocopies	retro_eeur_216, retro_eeur_344, retro_eeur_37,
Echinops telfairi	ENSETEG00000002967	1 retrocopy	retro_etel_1294,
Felis catus	ENSFCAG00000010347	1 retrocopy	retro_fcat_278,
Macaca mulatta	ENSMMUG00000004341	1 retrocopy	retro_mmul_1648,
Mustela putorius furo	ENSMPUG00000006859	3 retrocopies	retro_mputfur_1218, retro_mputfur_1615, retro_mputfur_192,
Mus musculus	ENSMUSG00000059436	8 retrocopies	retro_mmus_2891, retro_mmus_2892, retro_mmus_2893, retro_mmus_2894, retro_mmus_2991, retro_mmus_2992, retro_mmus_2993, retro_mmus_2994,
Nomascus leucogenys	ENSNLEG00000014373	1 retrocopy	retro_nleu_1122,
Ochotona princeps	ENSOPRG00000016245	1 retrocopy	retro_opri_945,
Pongo abelii	ENSPPYG00000005911	1 retrocopy	retro_pabe_3097,
Rattus norvegicus	ENSRNOG00000008049	3 retrocopies	retro_rnor_1653, retro_rnor_1877, retro_rnor_2369 ,
Ictidomys tridecemlineatus	ENSSTOG00000028142	1 retrocopy	retro_itri_42,
Tupaia belangeri	ENSTBEG00000012645	1 retrocopy	retro_tbel_3407,