RetrogeneDB ID: retro_btau_1187

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 29:17801610..17802294(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RNPS1
• Ensembl ID: ENSBTAG00000009969
• Aliases: None
• Description: RNA-binding protein with serine-rich domain 1 [Source:UniProtKB/Swiss-Prot;Acc:A6QR16]

Sequence

>retro_btau_1187
ACCAAACGCAAAGGCTGCTCTGATGAGAAGTCCAAGGATCGCTCTAAAGAAAAAGGGGCCTCCAAAGAGTCAAGCGAGAA
GGATGGTGGTGGGGATAAAACTCTCAAGAGCCACAGCGCTGCCAGTGGTAGCAGCAGCACCAGCTCTCCTCCAGCTCCTC
TTAGGTACTAGCCGCCCAGGAAGTTCCAGCACACCCCCCAGCCCCAGCAGCTCTGTGGCACCCCGAGTCGCACTCCTTCC
TGGTGTAGACAGACAACAGGAGGCATTCCTGTTCCAAATTGAAACCACCCAAGAGAGAAGGAAGGGACAGGAAAAGGGAG
CCGTTCCCTTATATCCACCAAGGAGCACACTGGGAGGCTGACCAGGAATGTGCCCAAGGATCATGTCGGGCGATCCTCTC
CAGCTTTGGGAAAATAAACATGATTGACGTGCCTCCAGAAAGGATGCACCCTCATCTGTCTAAAGGCTATGCCTGTGCGT
GGTTTGAGAATCCAGATGAAGCCCAGAAGGCACTAAAGCACAGGGATGGAGGACAAATGTGTGGCTGGGAGGATCACTGT
CACCACTGGGCTGGGTCCCTGGCCTCGGCCACCCACCGGGTGATTCAGCCCTGCCAGGAGAATGTCGCCACCGCCTCCCA
GGTGGCGCAAGTCACCCTGACGGTGCAGGAGAAGGTCATGGTCC

Alignment

ORF - retro_btau_1187 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 55.19 %
• Parental protein coverage: 76.72 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 7

Retrocopy - Parental Gene Alignment:

Parental  SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSS-GSSSS-SASSRSGSSS
          .K.KG...E.S.KDR...K.....S............S....SG...S...SS..SSSS....SR.GSSS
Retrocopy TKRKGCSDEKS-KDRSKEKGASKESSEKDGGGDKTLKSHSAASG---SSSTSS<SSSSS<LGTSRPGSSS

Parental  TSRSSSSSSS-SGSPSPSRRRH-DNRRRSRSKSKPPKRDEKERKRRSPSPK-PTKVHIGRLTRNVTKDHI
          T..S.SSS.....S..PS..R..DNRR.S.SK.KPPKR....RKR..P.P...TK.H.GRLTRNV.KDH.
Retrocopy TPPSPSSSVA<TPSRTPSWCRQ<DNRRHSCSKLKPPKREGRDRKRE-PFPY>STKEHTGRLTRNVPKDHV

Parental  -MEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQE-ITATAVLAPWPRP
          ...I.S..GKI.MID.P.ERMHPHLSKGYA...FENPDEA.KALKH.DGGQ..G.E.IT.T..L.PWPRP
Retrocopy <RAILSSFGKINMIDVPPERMHPHLSKGYACAWFENPDEAQKALKHRDGGQMCGWE>ITVTTGLGPWPRP

Parental  PPRRFSPPRRMLPPLPMWRRSPPRMRRRSRS
          P...FSP.RRM.PP.P.WR.SP.R.RRRS.S
Retrocopy PTG*FSPARRMSPPPPRWRKSP*RCRRRSWS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	38.07 RPM
ERP005899_muscle	0.11 RPM	64.03 RPM
SRP017611_brain	0.00 RPM	71.76 RPM
SRP017611_kidney	0.06 RPM	66.62 RPM
SRP017611_liver	0.00 RPM	43.49 RPM
SRP030211_testis	0.02 RPM	81.86 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1187 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1187 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1187 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 43 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000017861	1 retrocopy	retro_amel_194,
Bos taurus	ENSBTAG00000009969	7 retrocopies	retro_btau_1187 , retro_btau_1239, retro_btau_1283, retro_btau_1515, retro_btau_764, retro_btau_776, retro_btau_85,
Canis familiaris	ENSCAFG00000019397	1 retrocopy	retro_cfam_449,
Equus caballus	ENSECAG00000023288	1 retrocopy	retro_ecab_524,
Felis catus	ENSFCAG00000007690	1 retrocopy	retro_fcat_248,
Homo sapiens	ENSG00000205937	1 retrocopy	retro_hsap_2911,
Gorilla gorilla	ENSGGOG00000014275	1 retrocopy	retro_ggor_2016,
Macropus eugenii	ENSMEUG00000008882	1 retrocopy	retro_meug_1996,
Myotis lucifugus	ENSMLUG00000016808	3 retrocopies	retro_mluc_2237, retro_mluc_2618, retro_mluc_643,
Macaca mulatta	ENSMMUG00000019238	1 retrocopy	retro_mmul_794,
Monodelphis domestica	ENSMODG00000015891	1 retrocopy	retro_mdom_1171,
Mus musculus	ENSMUSG00000034681	1 retrocopy	retro_mmus_173,
Otolemur garnettii	ENSOGAG00000031582	1 retrocopy	retro_ogar_3241,
Rattus norvegicus	ENSRNOG00000008703	4 retrocopies	retro_rnor_1537, retro_rnor_2135, retro_rnor_2988, retro_rnor_649,
Sarcophilus harrisii	ENSSHAG00000016951	1 retrocopy	retro_shar_390,
Ictidomys tridecemlineatus	ENSSTOG00000013200	1 retrocopy	retro_itri_1160,
Tupaia belangeri	ENSTBEG00000009098	8 retrocopies	retro_tbel_1262, retro_tbel_1851, retro_tbel_2132, retro_tbel_2154, retro_tbel_2216, retro_tbel_3193, retro_tbel_3286, retro_tbel_4688,
Tarsius syrichta	ENSTSYG00000001629	1 retrocopy	retro_tsyr_957,
Tursiops truncatus	ENSTTRG00000008220	7 retrocopies	retro_ttru_1010, retro_ttru_1033, retro_ttru_1558, retro_ttru_1808, retro_ttru_1809, retro_ttru_203, retro_ttru_986,